Search result: Catalogue data in Spring Semester 2020

Statistics Master Information
The following courses belong to the curriculum of the Master's Programme in Statistics. The corresponding credits do not count as external credits even for course units where an enrolment at ETH Zurich is not possible.
Specialization Areas and Electives
Statistical and Mathematical Courses
NumberTitleTypeECTSHoursLecturers
636-0702-00LStatistical Models in Computational BiologyW6 credits2V + 1U + 2AN. Beerenwinkel
AbstractThe course offers an introduction to graphical models and their application to complex biological systems. Graphical models combine a statistical methodology with efficient algorithms for inference in settings of high dimension and uncertainty. The unifying graphical model framework is developed and used to examine several classical and topical computational biology methods.
ObjectiveThe goal of this course is to establish the common language of graphical models for applications in computational biology and to see this methodology at work for several real-world data sets.
ContentGraphical models are a marriage between probability theory and graph theory. They combine the notion of probabilities with efficient algorithms for inference among many random variables. Graphical models play an important role in computational biology, because they explicitly address two features that are inherent to biological systems: complexity and uncertainty. We will develop the basic theory and the common underlying formalism of graphical models and discuss several computational biology applications. Topics covered include conditional independence, Bayesian networks, Markov random fields, Gaussian graphical models, EM algorithm, junction tree algorithm, model selection, Dirichlet process mixture, causality, the pair hidden Markov model for sequence alignment, probabilistic phylogenetic models, phylo-HMMs, microarray experiments and gene regulatory networks, protein interaction networks, learning from perturbation experiments, time series data and dynamic Bayesian networks. Some of the biological applications will be explored in small data analysis problems as part of the exercises.
Lecture notesno
Literature- Airoldi EM (2007) Getting started in probabilistic graphical models. PLoS Comput Biol 3(12): e252. doi:10.1371/journal.pcbi.0030252
- Bishop CM. Pattern Recognition and Machine Learning. Springer, 2007.
- Durbin R, Eddy S, Krogh A, Mitchinson G. Biological Sequence Analysis. Cambridge university Press, 2004
701-0104-00LStatistical Modelling of Spatial DataW3 credits2GA. J. Papritz
AbstractIn environmental sciences one often deals with spatial data. When analysing such data the focus is either on exploring their structure (dependence on explanatory variables, autocorrelation) and/or on spatial prediction. The course provides an introduction to geostatistical methods that are useful for such analyses.
ObjectiveThe course will provide an overview of the basic concepts and stochastic models that are used to model spatial data. In addition, participants will learn a number of geostatistical techniques and acquire familiarity with R software that is useful for analyzing spatial data.
ContentAfter an introductory discussion of the types of problems and the kind of data that arise in environmental research, an introduction into linear geostatistics (models: stationary and intrinsic random processes, modelling large-scale spatial patterns by linear regression, modelling autocorrelation by variogram; kriging: mean square prediction of spatial data) will be taught. The lectures will be complemented by data analyses that the participants have to do themselves.
Lecture notesSlides, descriptions of the problems for the data analyses and solutions to them will be provided.
LiteratureP.J. Diggle & P.J. Ribeiro Jr. 2007. Model-based Geostatistics. Springer.

Bivand, R. S., Pebesma, E. J. & Gómez-Rubio, V. 2013. Applied Spatial Data Analysis with R. Springer.
Prerequisites / NoticeFamiliarity with linear regression analysis (e.g. equivalent to the first part of the course 401-0649-00L Applied Statistical Regression) and with the software R (e.g. 401-6215-00L Using R for Data Analysis and Graphics (Part I), 401-6217-00L Using R for Data Analysis and Graphics (Part II)) are required for attending the course.
401-6222-00LRobust and Nonlinear Regression Information Restricted registration - show details W2 credits1V + 1UA. F. Ruckstuhl
AbstractIn a first part, the basic ideas of robust fitting techniques are explained theoretically and practically using regression models and explorative multivariate analysis.

The second part addresses the challenges of fitting nonlinear regression functions and finding reliable confidence intervals.
ObjectiveParticipants are familiar with common robust fitting methods for the linear regression models as well as for exploratory multivariate analysis and are able to assess their suitability for the data at hand.

They know the challenges that arise in fitting of nonlinear regression functions, and know the difference between classical and profile based methods to determine confidence intervals.

They can apply the discussed methods in practise by using the statistics software R.
ContentRobust fitting: influence function, breakdown point, regression M-estimation, regression MM-estimation, robust inference, covariance estimation with high breakdown point, application in principal component analysis and linear discriminant analysis.

Nonlinear regression: the nonlinear regression model, estimation methods, approximate tests and confidence intervals, estimation methods, profile t plot, profile traces, parameter transformation, prediction and calibration
Lecture notesLecture notes are available
Prerequisites / NoticeIt is a block course on three Mondays in June
401-8618-00LStatistical Methods in Epidemiology (University of Zurich)
No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.
UZH Module Code: STA408

Mind the enrolment deadlines at UZH:
https://www.uzh.ch/cmsssl/en/studies/application/mobilitaet.html
W5 credits3GUniversity lecturers
AbstractAnalysis of case-control and cohort studies. The most relevant measures
of effect (odds and rate ratios) are introduced, and methods for
adjusting for confounders (Mantel-Haenszel, regression) are thoroughly
discussed. Advanced topics such as measurement error and propensity
score adjustments are also covered. We will outline statistical methods
for case-crossover and case series studies etc.
Objective
401-4626-00LAdvanced Statistical Modelling: Mixed ModelsW4 credits2VM. Mächler
AbstractMixed Models = (*| generalized| non-) linear Mixed-effects Models, extend traditional regression models by adding "random effect" terms.

In applications, such models are called "hierarchical models", "repeated measures" or "split plot designs". Mixed models are widely used and appropriate in an aera of complex data measured from living creatures from biology to human sciences.
Objective- Becoming aware how mixed models are more realistic and more powerful in many cases than traditional ("fixed-effects only") regression models.

- Learning to fit such models to data correctly, critically interpreting results for such model fits, and hence learning to work the creative cycle of responsible statistical data analysis:
"fit -> interpret & diagnose -> modify the fit -> interpret & ...."

- Becoming aware of computational and methodological limitations of these models, even when using state-of-the art software.
ContentThe lecture will build on various examples, use R and notably the `lme4` package, to illustrate concepts. The relevant R scripts are made available online.

Inference (significance of factors, confidence intervals) will focus on the more realistic *un*balanced situation where classical (ANOVA, sum of squares etc) methods are known to be deficient. Hence, Maximum Likelihood (ML) and its variant, "REML", will be used for estimation and inference.
Lecture notesWe will work with an unfinished book proposal from Prof Douglas Bates, Wisconsin, USA which itself is a mixture of theory and worked R code examples.

These lecture notes and all R scripts are made available from
https://github.com/mmaechler/MEMo
Literature(see web page and lecture notes)
Prerequisites / Notice- We assume a good working knowledge about multiple linear regression ("the general linear model') and an intermediate (not beginner's) knowledge about model based statistics (estimation, confidence intervals,..).

Typically this means at least two classes of (math based) statistics, say
1. Intro to probability and statistics
2. (Applied) regression including Matrix-Vector notation Y = X b + E

- Basic (1 semester) "Matrix calculus" / linear algebra is also assumed.

- If familiarity with [R](https://www.r-project.org/) is not given, it should be acquired during the course (by the student on own initiative).
447-6236-00LStatistics for Survival Data Restricted registration - show details W2 credits1V + 1UA. Hauser
AbstractThe primary purpose of a survival analysis is to model and analyze time-to-event data; that is, data that have as a principal endpoint the length of time for an event to occur. This block course introduces the field of survival analysis without getting too embroiled in the theoretical technicalities.
ObjectivePresented here are some frequently used parametric models and methods, including accelerated failure time models; and the newer nonparametric procedures which include the Kaplan-Meier estimate of survival and the Cox proportional hazards regression model. The statistical tools treated are applicable to data from medical clinical trials, public health, epidemiology, engineering, economics, psychology, and demography as well.
ContentThe primary purpose of a survival analysis is to model and analyze time-to-event data; that is, data that have as a principal endpoint the length of time for an event to occur. Such events are generally referred to as "failures." Some examples are time until an electrical component fails, time to first recurrence of a tumor (i.e., length of remission) after initial treatment, time to death, time to the learning of a skill, and promotion times for employees.

In these examples we can see that it is possible that a "failure" time will not be observed either by deliberate design or due to random censoring. This occurs, for example, if a patient is still alive at the end of a clinical trial period or has moved away. The necessity of obtaining methods of analysis that accommodate censoring is the primary reason for developing specialized models and procedures for failure time data. Survival analysis is the modern name given to the collection of statistical procedures which accommodate time-to-event censored data. Prior to these new procedures, incomplete data were treated as missing data and omitted from the analysis. This resulted in the loss of the partial information obtained and in introducing serious systematic error (bias) in estimated quantities. This, of course, lowers the efficacy of the study. The procedures discussed here avoid bias and are more powerful as they utilize the partial information available on a subject or item.

This block course introduces the field of survival analysis without getting too embroiled in the theoretical technicalities. Models for failure times describe either the survivor function or hazard rate and their dependence on explanatory variables. Presented here are some frequently used parametric models and methods, including accelerated failure time models; and the newer nonparametric procedures which include the Kaplan-Meier estimate of survival and the Cox proportional hazards regression model. The statistical tools treated are applicable to data from medical clinical trials, public health, epidemiology, engineering, economics, psychology, and demography as well.
401-8628-00LSurvival Analysis (University of Zurich)
No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.
UZH Module Code: STA425

Mind the enrolment deadlines at UZH:
http://www.uzh.ch/studies/application/mobilitaet_en.html
W3 credits1.5GUniversity lecturers
AbstractThe analysis of survival times, or in more general terms, the analysis
of time to event variables is concerned with models for censored
observations. Because we cannot always wait until the event of interest
actually happens, the methods discussed here are required for an
appropriate handling of incomplete observations where we only know that
the event of interest did not happen within ...
Objective
ContentDuring the course, we will study the most important methods and models
for censored data, including
- general concepts of censoring,
- simple summary statistics,
- estimation of survival curves,
- frequentist inference for two and more groups, and
- regression models for censored observations
Application Areas
Students select one area of application and look for suitable courses in which quantitative methods and modeling play a role. They need the consent by the Advisor (http://stat.ethz.ch/~kalisch/) that the chosen courses are eligible in the category "Application Areas".

For the category assignment of eligible courses keep the choice "no category" and take contact with the Study Administration Office (www.math.ethz.ch/studiensekretariat/staff/ekuenti) after having received the credits. The Study Administration Office needs the Advisor's consent.
Seminar or Semester Paper
NumberTitleTypeECTSHoursLecturers
401-4620-00LStatistics Lab Restricted registration - show details
Number of participants limited to 27.
W6 credits2SM. Kalisch, M. H. Maathuis, M. Mächler, L. Meier, N. Meinshausen
Abstract"Statistics Lab" is an Applied Statistics Workshop in Data Analysis. It
provides a learning environment in a realistic setting.

Students lead a regular consulting session at the Seminar für Statistik
(SfS). After the session, the statistical data analysis is carried out and
a written report and results are presented to the client. The project is
also presented in the course's seminar.
Objective- gain initial experience in the consultancy process
- carry out a consultancy session and produce a report
- apply theoretical knowledge to an applied problem

After the course, students will have practical knowledge about statistical
consulting. They will have determined the scientific problem and its
context, enquired the design of the experiment or data collection, and
selected the appropriate methods to tackle the problem. They will have
deepened their statistical knowledge, and applied their theoretical
knowledge to the problem. They will have gathered experience in explaining
the relevant mathematical and software issues to a client. They will have
performed a statistical analysis using R (or SPSS). They improve their
skills in writing a report and presenting statistical issues in a talk.
ContentStudents participate in consulting meetings at the SfS. Several consulting
dates are available for student participation. These are arranged
individually.

-During the first meeting the student mainly observes and participates in
the discussion. During the second meeting (with a different client), the
student leads the meeting. The member of the consulting team is overseeing
(and contributing to) the meeting.

-After the meeting, the student performs the recommended analysis, produces
a report and presents the results to the client.

-Finally, the student presents the case in the weekly course seminar in a
talk. All students are required to attend the seminar regularly.
Lecture notesn/a
LiteratureThe required literature will depend on the specific statistical problem
under investigation. Some introductory material can be found below.
Prerequisites / NoticePrerequisites:
Sound knowledge in basic statistical methods, especially regression and, if
possible, analysis of variance. Basic experience in Data Analysis with R.
401-3630-04LSemester Paper Restricted registration - show details
Successful participation in the course unit 401-2000-00L Scientific Works in Mathematics is required.
For more information, see www.math.ethz.ch/intranet/students/study-administration/theses.html
W4 credits6ASupervisors
AbstractSemester papers serve to delve into a problem in statistics and to study it with the appropriate methods or to compile and clearly exhibit a case study of a statistical evaluation.
Objective
401-3630-94LSemester Paper Restricted registration - show details
Successful participation in the course unit 401-2000-00L Scientific Works in Mathematics is required.
For more information, see www.math.ethz.ch/intranet/students/study-administration/theses.html
W4 credits6ASupervisors
AbstractSemester papers serve to delve into a problem in statistics and to study it with the appropriate methods or to compile and clearly exhibit a case study of a statistical evaluation.
Objective
401-3630-06LSemester Paper Restricted registration - show details
Successful participation in the course unit 401-2000-00L Scientific Works in Mathematics is required.
For more information, see www.math.ethz.ch/intranet/students/study-administration/theses.html
W6 credits9ASupervisors
AbstractSemester papers serve to delve into a problem in statistics and to study it with the appropriate methods or to compile and clearly exhibit a case study of a statistical evaluation.
Objective
401-3620-20LStudent Seminar in Statistics: Inference in Non-Classical Regression Models Restricted registration - show details
Number of participants limited to 24.
Mainly for students from the Mathematics Bachelor and Master Programmes who, in addition to the introductory course unit 401-2604-00L Probability and Statistics, have heard at least one core or elective course in statistics. Also offered in the Master Programmes Statistics resp. Data Science.
W4 credits2SF. Balabdaoui
AbstractReview of some non-standard regression models and the statistical properties of estimation methods in such models.
ObjectiveThe main goal is the students get to discover some less known regression models which either generalize the well-known linear model (for example monotone regression) or violate some of the most fundamental assumptions (as in shuffled or unlinked regression models).
ContentLinear regression is one of the most used models for prediction and hence one of the most understood in statistical literature. However, linearity might too simplistic to capture the actual relationship between some response and given covariates. Also, there are many real data problems where linearity is plausible but the actual pairing between the observed covariates and responses is completely lost or at partially. In this seminar, we review some of the non-classical regression models and the statistical properties of the estimation methods considered by well-known statisticians and machine learners. This will encompass:
1. Monotone regression
2. Single index model
3. Unlinked regression
4. Partially unlinked regression
Lecture notesNo script is necessary for this seminar
LiteratureIn the following is the material that will read and studied by each pair of students (all the items listed below are available through the ETH electronic library or arXiv):

1. Chapter 2 from the book "Nonparametric estimation under shape constraints" by P. Groeneboom and G. Jongbloed, 2014, Cambridge University Press

2. "Nonparametric shape-restricted regression" by A. Guntuoyina and B. Sen, 2018, Statistical Science, Volume 33, 568-594

3. "Asymptotic distributions for two estimators of the single index model" by Y. Xia, 2006, Econometric Theory, Volume 22, 1112-1137

4. "Least squares estimation in the monotone single index model" by F. Balabdaoui, C. Durot and H. K. Jankowski, Journal of Bernoulli, 2019, Volume 4B, 3276-3310

5. "Least angle regression" by B. Efron, T. Hastie, I. Johnstone, and R. Tibshirani, 2004, Annals of Statsitics, Volume 32, 407-499.

6. "Sharp thresholds for high dimensional and noisy sparsity recovery using l1-constrained quadratic programming (Lasso)" by M. Wainwright, 2009, IEEE transactions in Information Theory, Volume 55, 1-19

7."Denoising linear models with permuted data" by A. Pananjady, M. Wainwright and T. A. Courtade and , 2017, IEEE International Symposium on Information Theory, 446-450.

8. "Linear regression with shuffled data: statistical and computation limits of permutation recovery" by A. Pananjady, M. Wainwright and T. A. Courtade , 2018, IEEE transactions in Information Theory, Volume 64, 3286-3300

9. "Linear regression without correspondence" by D. Hsu, K. Shi and X. Sun, 2017, NIPS

10. "A pseudo-likelihood approach to linear regression with partially shuffled data" by M. Slawski, G. Diao, E. Ben-David, 2019, arXiv.

11. "Uncoupled isotonic regression via minimum Wasserstein deconvolution" by P. Rigollet and J. Weed, 2019, Information and Inference, Volume 00, 1-27
401-3940-20LStudent Seminar in Mathematics and Data: Optimization of Random Functions Restricted registration - show details
Number of participants limited to 12.
W4 credits2SA. Bandeira
AbstractMore information at course webpage:
https://people.math.ethz.ch/~abandeira/Spring2020.StudentSeminar.html
Objective
363-1100-00LRisk Case Study Challenge Restricted registration - show details
Does not take place this semester.
W3 credits2SA. Bommier, S. Feuerriegel
AbstractThis seminar provides master students at ETH with the challenging opportunity of working on a real risk modelling and risk management case in close collaboration with a Risk Center Partner Company. For the Spring 2019 Edition the Partner will be Zurich Insurance Group.
ObjectiveStudents work on a real risk-related case of a business relevant topic provided by experts from Risk Center partners. While gaining substantial insights into the risk modeling and management of the industry, students explore the case or problem on their own, working in teams, and develop possible solutions. The cases allow students to use logical problem solving skills with emphasis on evidence and application and involve the integration of scientific knowledge. Typically, the risk-related cases can be complex, cover ambiguities, and may be addressed in more than one way. During the seminar students visit the partners’ headquarters, conduct interviews with members of the management team as well as internal and external experts, and present their results.
ContentGet a basic understanding of
o The insurance and reinsurance business
o Risk management and risk modelling
o The role of operational risk management

Get in contact with industry experts and conduct interviews on the topic.

Conduct a small empirical study and present findings to the company
Prerequisites / NoticePlease apply for this course via the official website (www.riskcenter.ethz.ch/education/lectures/risk-case-study-challenge-.html). Apply no later than February 15, 2019.
The number of participants is limited to 14.
GESS Science in Perspective
Two credits are needed from the "Science in Perspective" programme with language courses excluded if three credits from language courses have already been recognised for the Bachelor's degree.
see Link (Eight credits must be acquired in this category: normally six during the Bachelor’s degree programme, and two during the Master’s degree programme. A maximum of three credits from language courses from the range of the Language Center of the University of Zurich and ETH Zurich may be recognised. In addition, only advanced courses (level B2 upwards) in the European languages English, French, Italian and Spanish are recognised. German language courses are recognised from level C2 upwards.)
» see Science in Perspective: Type A: Enhancement of Reflection Capability
» Recommended Science in Perspective (Type B) for D-MATH
» see Science in Perspective: Language Courses ETH/UZH
Master's Thesis
NumberTitleTypeECTSHoursLecturers
401-2000-00LScientific Works in Mathematics
Target audience:
Third year Bachelor students;
Master students who cannot document to have received an adequate training in working scientifically.
O0 creditsÖ. Imamoglu, E. Kowalski
AbstractIntroduction to scientific writing for students with focus on publication standards and ethical issues, especially in the case of citations (references to works of others.)
ObjectiveLearn the basic standards of scientific works in mathematics.
Content- Types of mathematical works
- Publication standards in pure and applied mathematics
- Data handling
- Ethical issues
- Citation guidelines
Lecture notesMoodle of the Mathematics Library: https://moodle-app2.let.ethz.ch/course/view.php?id=519
Prerequisites / NoticeDirective Link
401-2000-01LLunch Sessions – Thesis Basics for Mathematics Students
Details and registration for the optional MathBib training course: https://www.math.ethz.ch/mathbib-schulungen
Z0 creditsSpeakers
AbstractOptional course "Recherchieren in der Mathematik" (held in German) by the Mathematics Library.
Objective
401-4990-02LMaster's Thesis Restricted registration - show details
Only students who fulfil the following criteria are allowed to begin with their Master's thesis:
a. successful completion of the Bachelor's programme;
b. fulfilling of any additional requirements necessary to gain admission to the Master's programme;
c. They have acquired at least 16 credits in the category ‘Core courses‘.

Successful participation in the course unit 401-2000-00L Scientific Works in Mathematics is required.
For more information, see www.math.ethz.ch/intranet/students/study-administration/theses.html
O30 credits57DSupervisors
AbstractThe master's thesis concludes the study programme. Thesis work should prove the students' ability to independent, structured and scientific working.
ObjectiveDie Studierenden sollen mit der Master-Arbeit, die den Abschluss des Studiengangs bildet, ihre Fähigkeit zu selbständiger, strukturierter und wissenschaftlicher Tätigkeit unter Beweis stellen.
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