Suchergebnis: Katalogdaten im Herbstsemester 2018

Doktorat Departement Maschinenbau und Verfahrenstechnik Information
Mehr Informationen unter: Link
Lehrangebot Doktorat und Postdoktorat
NummerTitelTypECTSUmfangDozierende
401-0625-01LApplied Analysis of Variance and Experimental Design Information W5 KP2V + 1UL. Meier
KurzbeschreibungPrinciples of experimental design, one-way analysis of variance, contrasts and multiple comparisons, multi-factor designs and analysis of variance, complete block designs, Latin square designs, random effects and mixed effects models, split-plot designs, incomplete block designs, two-series factorials and fractional designs, power.
LernzielParticipants will be able to plan and analyze efficient experiments in the fields of natural sciences. They will gain practical experience by using the software R.
InhaltPrinciples of experimental design, one-way analysis of variance, contrasts and multiple comparisons, multi-factor designs and analysis of variance, complete block designs, Latin square designs, random effects and mixed effects models, split-plot designs, incomplete block designs, two-series factorials and fractional designs, power.
LiteraturG. Oehlert: A First Course in Design and Analysis of Experiments, W.H. Freeman and Company, New York, 2000.
Voraussetzungen / BesonderesThe exercises, but also the classes will be based on procedures from the freely available, open-source statistical software R, for which an introduction will be held.
535-0546-00LPatentsW1 KP1VA. Koepf, P. Pliska
KurzbeschreibungKenntnisse auf dem Gebiet des gewerblichen Rechtsschutzes, insbesondere der Patente und Marken, unter besonderer Berücksichtigung des Pharmabereichs.
Einführung in den gewerblichen Rechtsschutz; Erlangung von Patenten; Patentinformation; Verwertung und Durchsetzung von Patenten; Besonderheiten im Pharma- und Medizinbereich; soziale, politische und ethische Aspekte; Marken.
LernzielMitsprachekompetenz auf dem Gebiet des gewerblichen Rechtsschutzes, insbesondere der Patente und Marken, unter besonderer Berücksichtigung des Chemie-, Pharma- und Biotech-Bereichs.
Inhalt1. Einführung in den gewerblichen Rechtsschutz (Patente, Marken, Designs);
2. Erlangung von Patenten (Patentierbarkeit, Patentanmeldung);
3. Patentinformation (Patentpublikationen, Datenbanken, Recherchen);
4. Verwertung und Durchsetzung von Patenten (Verwertungsmöglichkeiten, Lizenzen, Parallelimporte, Schutzbereich, Patentverletzung);
5. Besonderheiten im Pharma- und Medizinbereich (ergänzende Schutzzertifikate, Versuchsprivileg, Therapie und Diagnose, medizinische Indikation);
6. Soziale, politische und ethische Aspekte (Patente und Arzneimittelpreise, traditionelles Wissen und Ethnomedizin, Bioprospecting und Biopiraterie, Eigentum an Human-DNA-Erfindungen);
7. Marken, Markenarten, Ausschlussgründe, Besonderheiten von Pharmamarken.
SkriptSkript wird während der Vorlesung elektronisch zur Verfügung gestellt.
Literatur- CH-Patentgesetz: Link
- CH-Markenschutzgesetz: Link
- CH-Designgesetz: Link
- Europäisches Patenübereinkommen: Link
- Patentzusammenarbeitsvertrag: Link
- Eidgenössisches Institut für Geistiges Eigentum: Link
- Europäisches Patentamt: Link
- World Intellectual Property Organization: Link
636-0507-00LSynthetic Biology II Belegung eingeschränkt - Details anzeigen
Students in the MSc Programme Biotechnology (Programme Regulation 2017) may select Synthetic Biology II instead of the Research Project 1.
W8 KP4AS. Panke, Y. Benenson, J. Stelling
Kurzbeschreibung7 months biological design project, during which the students are required to give presentations on advanced topics in synthetic biology (specifically genetic circuit design) and then select their own biological system to design. The system is subsequently modeled, analyzed, and experimentally implemented. Results are presented at an international student competition at the MIT (Cambridge).
LernzielThe students are supposed to acquire a deep understanding of the process of biological design including model representation of a biological system, its thorough analysis, and the subsequent experimental implementation of the system and the related problems.
InhaltPresentations on advanced synthetic biology topics (eg genetic circuit design, adaptation of systems dynamics, analytical concepts, large scale de novo DNA synthesis), project selection, modeling of selected biological system, design space exploration, sensitivity analysis, conversion into DNA sequence, (DNA synthesis external,) implementation and analysis of design, summary of results in form of scientific presentation and poster, presentation of results at the iGEM international student competition (Link).
SkriptHandouts during course
Voraussetzungen / BesonderesThe final presentation of the project is typically at the MIT (Cambridge, US). Other competing schools include regularly Imperial College, Cambridge University, Harvard University, UC Berkeley, Princeton Universtiy, CalTech, etc.

This project takes place between end of Spring Semester and beginning of Autumn Semester. Registration in April.

Please note that the number of ECTS credits and the actual work load are disconnected.
851-0180-00LResearch Ethics Belegung eingeschränkt - Details anzeigen
Number of participants limited to 40

Particularly suitable for students of D-BIOL, D-CHAB, D-HEST
W2 KP2GG. Achermann
KurzbeschreibungThis course enables students to:
• Identify and describe leading approaches to and key questions and concepts of research ethics;
• Identify, construct and evaluate moral arguments;
• Make well-reasoned decisions to ethical problems a scientist is likely to encounter;
• Analyze the theoretical foundations and disputes underlying contemporary debates on moral issues in research.
LernzielParticipants of the course Research Ethics will
• Develop an understanding of the role of certain moral concepts, principles and normative theories related to scientific research;
• Improve their moral reasoning skills (such as identifying and evaluating reasons, conclusions, assumptions, analogies, concepts and principles), and their ability to use these skills in assessing other people’s arguments, making decisions and constructing their own reasoning to the kinds of ethical problems a scientist is likely to encounter;
• Deepen their understanding of the debates on certain central moral issues in research, e.g. the use of animals in biomedical research.
InhaltI. Introduction to Moral Reasoning
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1. Ethics - the basics
- What is ethics? What ethics is not...
- Identification of moral issues (awareness): what constitutes an ethical question? Distinguishing ethical questions from other kinds of questions;
- Values (personal, cultural & ethical) & principles for ethical conduct in research;
- Descriptive and prescriptive ethics
- Ethical universalism, ethical relativism and cultural relativism
- What is research ethics and why is it important?
- Professional codes of conduct: functions and limitations

2. Normative Ethics
- Overview on important theories for research ethics: virtue theories, duty-based theories (rights theory, categorical imperative, prima facie duties), consequentialist theories, other theories;
- The plurality of ethical theories, moral pluralism and its consequences;

3. Arguments
- Why arguments? What is a good argument? The structure of (moral) arguments;
- Deductive and inductive arguments; Validity and soundness; strength and cogency;
- Assessing moral arguments

II. Research Ethics
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1. Research involving animals
- The moral status of animals: moral considerability (morally relevant features), moral significance;
- Representative views (indirect theories, direct but unequal theories, and moral equality theories) on the moral status of animals and resulting standpoints on the use of animals in biomedical research
- The 3 R's (replacement, reduction, refinement);
- Public policy in the context of moral disagreement
- The concept of dignity and the dignity of living beings in the Swiss constitution;
- The weighing/evaluation of interests: the procedure and criticism, the value of basic research and related problems in the weighing of interests;

2. Research involving human subjects
- History of research involving human subjects
- Basic ethical principles – the Belmont report
- Selection of study participants. The concept of vulnerability
- Assessment of risks and benefits of a research project
- Research ethics committees
- Information and consent; confidentiality and anonymity;
- Research projects involving biological material and health related data

3. Social responsibility
- What is social responsibility? Social responsibility: whose obligation?
- Public advocacy by researchers
SkriptCourse material (handouts, case studies, exercises, surveys and papers) will be available during the lectures and on the course homepage.
Voraussetzungen / BesonderesWhat are the requirements?
First and foremost your strong willingness to seriously achieve the main learning outcomes as indicated in the Course Catalogue (specific learning outcomes for each module will be provided at the beginning of the course). For successfully completing the course Research Ethics, the following commitment is absolutely necessary (but not sufficient) (observed success factors for many years!):
1. Your regular presence is absolutely required (so please no double, parallel enrollment for courses taking place at the identical time!) connected with your active participation during class, e.g. taking notes, contributing to discussions (in group as well as in plenary class), solving exercises.
2. Having the willingness and availability of the necessary time for regularly preparing the class (at least 1 hour per week, probably even more…).
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