Search result: Catalogue data in Autumn Semester 2016
Biomedical Engineering Master | ||||||
Track Courses | ||||||
Bioelectronics | ||||||
Recommended Elective Courses These courses are particularly recommended for the Bioelectronics track. Please consult your track advisor if you wish to select other subjects. | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
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376-1351-00L | Micro/Nanotechnology and Microfluidics for Biomedical Applications | W | 2 credits | 2V | E. Delamarche | |
Abstract | This course is an introduction to techniques in micro/nanotechnology and to microfluidics. It reviews how many familiar devices are built and can be used for research and biomedical applications. Transistors for DNA sequencing, beamers for patterning proteins, hard-disk technology for biosensing and scanning microfluidics for analyzing tissue sections are just a few examples of the covered topics. | |||||
Objective | The main objective of the course is to introduce micro/nanotechnology and microfluidics to students having a background in the life sciences. The course should familiarize the students with the techniques used in micro/nanotechnology and show them how micro/nanotechnology pervades throughout life sciences. Microfluidics will be emphasized due to their increasing importance in research and medical applications. The second objective is to have life students less intimidated by micro/nanotechnology and make them able to link instruments and techniques to specific problems that they might have in their projects/studies. This will also help students getting access to the ETHZ/IBM Nanotech Center infrastructure if needed. | |||||
Content | Mostly formal lectures (2 × 45 min), with a 2 hour visit and introduction to cleanroom and micro/nanotechnology instruments, last 3 sessions would be dedicated to the presentation and evaluation of projects by students (3 students per team). | |||||
Prerequisites / Notice | Nanotech center and lab visit at IBM would be mandatory, as well as attending the student project presentations. | |||||
529-0837-00L | Biomicrofluidic Engineering Number of participants limited to 30. | W | 7 credits | 3G | A. de Mello | |
Abstract | Microfluidics describes the behaviour, control and manipulation of fluids that are geometrically constrained within sub-microliter environments. The use of microfluidic devices offers an opportunity to control physical and chemical processes with unrivalled precision, and in turn provides a route to performing chemistry and biology in an ultra-fast and high-efficiency manner. | |||||
Objective | In the course students will investigate the theoretical concepts behind microfluidic device operation, the methods of microfluidic device manufacture and the application of microfluidic architectures to important problems faced in modern day chemical and biological analysis. A design workshop will allow students to develop new microscale flow processes by appreciating the dominant physics at the microscale. The application of these basic ideas will primarily focus on biological problems and will include a treatment of diagnostic devices for use at the point-of-care, advanced functional material synthesis, DNA analysis, proteomics and cell-based assays. Lectures, assignments and the design workshop will acquaint students with the state-of-the-art in applied microfluidics. | |||||
Content | Specific topics in the course include, but not limited to: 1. Theoretical Concepts Features of mass and thermal transport on the microscale Key scaling laws 2. Microfluidic Device Manufacture Conventional lithographic processing of rigid materials Soft lithographic processing of plastics and polymers Mass fabrication of polymeric devices 3. Unit operations and functional components Analytical separations (electrophoresis and chromatography) Chemical and biological synthesis Sample pre-treatment (filtration, SPE, pre-concentration) Molecular detection 4. Design Workshop Design of microfluidic architectures for PCR, distillation & mixing 5. Contemporary Applications in Biological Analysis Microarrays Cellular analyses (single cells, enzymatic assays, cell sorting) Proteomics 6. System integration Applications in radiochemistry, diagnostics and high-throughput experimentation | |||||
Lecture notes | Lecture handouts, background literature, problem sheets and notes will be provided electronically. | |||||
636-0003-00L | Biological Engineering and Biotechnology | W | 6 credits | 3V | M. Fussenegger | |
Abstract | Biological Engineering and Biotechnology will cover the latest biotechnological advances as well as their industrial implementation to engineer mammalian cells for use in human therapy. This lecture will provide forefront insights into key scientific aspects and the main points in industrial decision-making to bring a therapeutic from target to market. | |||||
Objective | 1. Insight Into The Mammalian Cell Cycle. Cycling, The Balance Between Proliferation and Cancer - Implications For Biopharmaceutical Manufacturing. 2. The Licence To Kill. Apoptosis Regulatory Networks - Engineering of Survival Pathways To Increase Robustness of Production Cell Lines. 3. Everything Under Control I. Regulated Transgene Expression in Mammalian Cells - Facts and Future. 4. Secretion Engineering. The Traffic Jam getting out of the Cell. 5. From Target To Market. An Antibody's Journey From Cell Culture to The Clinics. 6. Biology and Malign Applications. Do Life Sciences Enable the Development of Biological Weapons? 7. Functional Food. Enjoy your Meal! 8. Industrial Genomics. Getting a Systems View on Nutrition and Health - An Industrial Perspective. 9. IP Management - Food Technology. Protecting Your Knowledge For Business. 10. Biopharmaceutical Manufacturing I. Introduction to Process Development. 11. Biopharmaceutical Manufacturing II. Up- stream Development. 12. Biopharmaceutical Manufacturing III. Downstream Development. 13. Biopharmaceutical Manufacturing IV. Pharma Development. | |||||
Lecture notes | Handsout during the course. | |||||
Biology Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
227-0399-10L | Physiology and Anatomy for Biomedical Engineers I | W | 3 credits | 2G | H. Niemann | |
Abstract | This course offers an introduction into the structure and function of the human body, and how these are interlinked with one another. Focusing on physiology, the visualization of anatomy is supported by 3D-animation, Computed Tomography and Magnetic Resonance imaging. | |||||
Objective | To understand basic principles and structure of the human body in consideration of the clinical relevance and the medical terminology used in medical work and research. | |||||
Content | - The Human Body: nomenclature, orientations, tissues - Musculoskeletal system, Muscle contraction - Blood vessels, Heart, Circulation - Blood, Immune system - Respiratory system - Acid-Base-Homeostasis | |||||
Lecture notes | Lecture notes and handouts | |||||
Literature | Silbernagl S., Despopoulos A. Color Atlas of Physiology; Thieme 2008 Faller A., Schuenke M. The Human Body; Thieme 2004 Netter F. Atlas of human anatomy; Elsevier 2014 | |||||
227-0945-00L | Cell and Molecular Biology for Engineers I This course is part I of a two-semester course. | W | 3 credits | 3G | C. Frei | |
Abstract | The course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology. | |||||
Objective | After completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested. | |||||
Content | Lectures will include the following topics: DNA, chromosomes, RNA, protein, genetics, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer, development and stem cells. In addition, three journal clubs will be held, where one/two publictions will be discussed (part I: 1 Journal club, part II: 2 Journal Clubs). For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded and count as 25% for the final grade. | |||||
Lecture notes | Scripts of all lectures will be available. | |||||
Literature | "Molecular Biology of the Cell" (6th edition) by Alberts, Johnson, Lewis, Raff, Roberts, and Walter. | |||||
227-0949-00L | Biological Methods for Engineers (Basic Lab) Limited number of participants. | W | 2 credits | 4P | C. Frei | |
Abstract | The course during 4 afternoons (13h to 18h) covers basic laboratory skills and safety, cell culture, protein analysis, RNA/DNA Isolation and RT-PCR. Each topic will be introduced, followed by practical work at the bench. Presence during the course is mandatory. | |||||
Objective | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | |||||
Content | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | |||||
Prerequisites / Notice | Enrollment is limited and students from the Master's programme in Biomedical Engineering (BME) have priority. |
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