Suchergebnis: Katalogdaten im Herbstsemester 2022
Biologie Master  | |||||||||||||||||||||||||||||||||||||||||||||||||||
 Wahlvertiefungen | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wahlvertiefung: Mikrobiologie und Immunologie | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Zusätzliche Konzeptkurse | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | ||||||||||||||||||||||||||||||||||||||||||||||
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| 752-4005-00L | Lebensmittel-Mikrobiologie I | W | 3 KP | 2V | M. Loessner | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Diese Vorlesung ist der erste Teil eines Jahreskurses. Vermittelt wird ein vertiefter Ueberblick in die Grundlagen und praktischen Aspekte der Lebensmittel-Mikrobiologie, mikrobiologische Kenntnisse ueber die vielfältigen Bakterien, Hefen und Schimmel in Lebensmitteln, das Vorkommen und die Kontrolle von Krankheitserregern und Verderbniserregern. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Die Vorlesung bietet einen vertieften Ueberblick in die Grundlagen und praktischen Aspekte der Lebenmittel-Mikrobiologie. Vermittelt werden mikrobiologische Kenntnisse ueber die vielfältigen Bakterien, Hefen, Schimmel und Protozoen in Lebenmitteln, das Vorkommen und die Kontrolle von Krakheitserregern und Verderbniserregern. Besonderer Schwerpunkt dieses ersten Vorlesungsteils (LM Mikrobio II wird im FS angeboten) liegt auf den Organismen selber, und den Faktoren welche verderb und Krankheiten bedingen. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | 1. Kurze Geschichte der Lebensmittelmikrobiologie 1.1. Geschichte der Mikroorganismen in Lebensmitteln 1.2. Verderb von Lebensmitteln 1.3. Lebensmittelvergiftungen 1.4. Lebensmittelkonservierung 1.5. VIP's der Lebensmittelmikrobiologie 2. Übersicht über Mikroorganismen in Lebensmitteln 2.1 Herkunft der Mikroorganismen in LM 2.2. Bakterien 2.3. Schimmel 2.4. Hefen 3. Mikrobieller Verderb von Lebensmitteln 3.1. Intrinsische & extrinsische Parameter 3.2. Fleisch und Fleischprodukte, Fisch, Eier 3.3. Milch und Milchprodukte 3.4. Pflanzliche Produkte (Obst , Gemüse, Getreide) 3.5. Verschiedenes (Backwaren, Süsswaren, Nüsse, Gewürze, Fertigprodukte) 3.6. Getränke und Konserven 4. Krankheitserreger in Lebensmitteln 4.1. Bedeutung und Transmissionsrouten (MO > LM > Mensch) 4.2. Staphylococcus aureus 4.3. Gram-positive Sporenbildner (Bacillus & Clostridium) 4.4. Listeria monocytogenes 4.5. Salmonella, Shigella, Escherichia coli 4.6. Vibrio, Yersinia, Campylobacter 4.7. Brucella, Mycobacterium 4.8. Tierische Parasiten und Einzeller 4.9. Viren und Bakteriophagen 4.10. Mykotoxine 4.11. Biogene Amine 4.12. Verschiedenes (Antibiotikaresistente Bakterien, Biofilme) | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Elektronische Kopien der Praesentationsfolien (PDF) sowie Zusatzmaterial wird zum Download bereitgestellt. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Hinweise in der ersten Vorlesungsstunde. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 701-2413-00L | Evolutionary Genetics | W | 6 KP | 4V | T. Städler, A. Widmer, S. Fior, M. Fischer, J. Stapley | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | The concept course 'Evolutionary Genetics' consists of two lectures that jointly provide an introduction to the fields of population and quantitative genetics (emphasis on basic concepts) and ecological genetics (more emphasis on evolutionary and ecological processes of adaptation and speciation). | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | The aim of the course is to provide students with a solid introduction to the fields of population genetics, quantitative genetics, and ecological genetics. The concepts and research methods developed in these fields have undergone profound transformations; they are of fundamental importance in our understanding of evolutionary processes, both past and present. Students should gain an appreciation for the concepts, methods and explanatory power of evolutionary genetics. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Population genetics - Types and sources of genetic variation; randomly mating populations and the Hardy-Weinberg equilibrium; effects of inbreeding; natural selection; random genetic drift and effective population size; gene flow and hierarchical population structure; molecular population genetics: neutral theory of molecular evolution and basics of coalescent theory. Quantitative genetics - Continuous variation; measurement of quant. characters; genes, environments and their interactions; measuring their influence; response to selection; inbreeding and crossbreeding, effects on fitness; Fisher's fundamental theorem. Ecological Genetics - Concepts and methods for the study of genetic variation and its role in adaptation, reproductive isolation, hybridization and speciation | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Handouts | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Hamilton, M.B. 2009. Population Genetics. Wiley-Blackwell, Chichester, U.K. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0311-00L | Molecular Life of Plants | W | 6 KP | 4V | S. C. Zeeman, K. Bomblies, O. Voinnet | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | The advanced course introduces students to plants through a concept-based discussion of developmental processes that integrates physiology and biochemistry with genetics, molecular biology, and cell biology. The course follows the life of the plant, starting with the seed, progressing through germination to the seedling and mature plant, and ending with reproduction and senescence. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | The new course "Molecular Life of Plants" reflects the rapid advcances that are occurring in the field of experimental plant biology as well as the changing interests of students being trained in this discipline. Contemporary plant biology courses emphasize a traditional approach to experimental plant biology by discussing discrete topics that are removed from the context of the plant life cycle. The course will take an integrative approach that focuses on developmental concepts. Whereas traditional plant physiology courses were based on research carried out on intact plants or plant organs and were often based on phenomenological observations, current research in plant biology emphasizes work at the cellular, subcellular and molecular levels. The goal of "Molecular Life of Plants" is to train students in integrative approaches to understand the function of plants in a developmental context. While the course focuses on plants, the training integrative approaches will also be useful for other organisms. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | The course "Molecular Life of Plants" will cover the following topics: Plant genome organization and evolution Plant functional genomics and systems biology Plant genome engineering and editing Seed development and embryogenesis Root apical meristem: structure, function and hormone regulation Shoot apical meristem: structure, function and hormone regulation Mobilization of seed reserves Heterotrophic to autotrophic growth Chloroplast biogenesis and light perception Photosynthetic and central carbon metabolism Integration of carbon and nitrogen metabolism Principles of RNA silencing MicroRNAs: discovery and modes of action RNA silencing and pathogen defense RNA silencing movement, amplification and trans-generational silencing Plants and the environment Plant-pathogen interactions: pathogen attack, first layers of plant defense and plant responses Senescence | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0307-00L | Molecular and Structural Biology I: Protein Structure and Function D-BIOL students are obliged to take part I and part II (next semester) as a two-semester course | W | 3 KP | 2V | R. Glockshuber, K. Locher, E. Weber-Ban | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Biophysik der Proteinfaltung, Membranproteine und Biophysik von Membranen, enzymatischen Katalyse, katalytische RNA und RNAi, aktuelle Themen in Proteinbiophysik und Strukturbiologie. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Verständnis von Struktur/Funktionsbeziehungen in Proteinen, Proteinfaltung, Vertiefung der Kenntnisse in Biophysik, in physikalischen Messmethoden und modernen Methoden der Proteinreinigung und Protein-Mikroanalytik. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Skripte zu einzelnen Themen der Vorlesung sind unter http://www.mol.biol.ethz.ch/teaching abgelegt. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Grundlagen: - Creighton, T.E., Proteins, Freeman, (1993). - Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman. - Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001). Aktuelle Themen: Literatur wird jeweils in der Vorlesung angegeben | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0309-00L | Concepts in Modern Genetics Information for UZH students: Enrolment to this course unit only possible at ETH. No enrolment to module BIO348 at UZH. Please mind the ETH enrolment deadlines for UZH students: Link | W | 6 KP | 4V | Y. Barral, D. Bopp, A. Hajnal, O. Voinnet | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Concepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | This course focuses on the concepts of classical and modern genetics and genomics. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | The topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Scripts and additional material will be provided during the semester. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0319-00L | Cellular Biochemistry (Part I) | W | 3 KP | 2V | U. Kutay, G. Neurohr, M. Peter, I. Zemp | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Concepts and molecular mechanisms underlying the biochemistry of the cell, providing advanced insights into structure, function and regulation of individual cell components. Particular emphasis will be put on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes such as intracellular transport, cell division & growth, and cell migration. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | The full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterisation of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry. The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain the integration of different molecules and signaling pathways into complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, cell division and cell growth. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Structural and functional details of individual cell components, regulation of their interactions, and various aspects of the regulation and compartmentalisation of biochemical processes. Topics include: biophysical and electrical properties of membranes; viral membranes; structural and functional insights into intracellular transport and targeting; vesicular trafficking and phagocytosis; post-transcriptional regulation of gene expression. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Scripts and additional material will be provided during the semester. Please contact Dr. Alicia Smith for assistance with the learning materials. (alicia.smith@bc.biol.ethz.ch) | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Recommended supplementary literature (review articles and selected primary literature) will be provided during the course. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | To attend this course the students must have a solid basic knowledge in chemistry, biochemistry and general biology. The course will be taught in English. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-1299-00L | Bioinformatics  | W | 6 KP | 4G | S. Sunagawa, P. Beltrao, A. Blasimme, V. Boeva, A. Kahles, C. von Mering, N. Zamboni | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Students will study bioinformatic concepts in the areas of genomics, metagenomics, proteomics, biological networks, biostatistics and bioethics. Through integrated lectures, practical hands-on sessions and homework assignments, students will also be trained in analytical and programming skills to meet the emerging increase in data-driven knowledge generation in biology in the 21st century. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Students will have an advanced understanding of the underlying concepts behind modern bioinformatic analyses at genome, metagenome and proteome-wide scales. They will be familiar with the most common data types, where to access them, and how to analytically work with them to address contemporary questions in the field of biology. | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | Course participants have already acquired basic programming skills in UNIX, Python and R. Students bring their own computer with keyboard, internet access (browser) and software to connect to the ETH network via VPN. | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| 529-0731-00L | Nucleic Acids and Carbohydrates Hinweis für BSc Biologiestudierende: Nur einer der beiden Konzeptkurse 529-0731-00 Nucleic Acids and Carbohydrates (Herbstsemester) oder 529-0732-00 Proteins and Lipids (Frühlingsemester) kann für das Bachelorstudium angerechnet werden. | W | 6 KP | 3G | K. Lang, P. A. Kast, S. J. Sturla, H. Wennemers | ||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Struktur, Funktion und Chemie von Nukleinsäuren und Kohlenhydraten. DNA/RNA Struktur und Synthese; rekombinante DNA Technologie und PCR; DNA Arrays und Genomics; Antisense Ansatz und RNAi; Polymerasen und Transkriptionsfaktoren; katalytische RNA; DNA Schädigung und Reparatur; Kohlenhydratstruktur und Synthese; Kohlenhydratarrays; Cell Surface Engineering; Kohlenhydratimpfstoffe | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Struktur, Funktion und Chemie von Nukleinsäuren und Kohlenhydraten. DNA/RNA Struktur und Synthese; rekombinante DNA Technologie und PCR; DNA Arrays und Genomics; Antisense Ansatz und RNAi; Polymerasen und Transkriptionsfaktoren; katalytische RNA; DNA Schädigung und Reparatur; Kohlenhydratstruktur und Synthese; Kohlenhydratarrays; Cell Surface Engineering; Kohlenhydratimpfstoffe | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Struktur, Funktion und Chemie von Nukleinsäuren und Kohlenhydraten. DNA/RNA Struktur und Synthese; rekombinante DNA Technologie und PCR; DNA Arrays und Genomics; Antisense Ansatz und RNAi; Polymerasen und Transkriptionsfaktoren; katalytische RNA; DNA Schädigung und Reparatur; Kohlenhydratstruktur und Synthese; Kohlenhydratarrays; Cell Surface Engineering; Kohlenhydratimpfstoffe | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Kein Skript; Illustrationen aus der Originalliteratur passend zu den behandelten Themen werden wöchentlich zur Verfügung gestellt (in der Regel als Handouts auf dem Moodle Server). | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Hauptsächlich basierend auf Originalliteratur, eine detaillierte Liste wird in der Vorlesung ausgeteilt | ||||||||||||||||||||||||||||||||||||||||||||||||||
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