Search result: Catalogue data in Spring Semester 2021
Chemistry Bachelor  | ||||||
 4. Semester | ||||||
| Compulsory Subjects Examination Block I | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|---|
| 529-0122-00L | Inorganic Chemistry II | O | 3 credits | 3G | M. Kovalenko, K. Kravchyk | |
| Abstract | The lecture is based on Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers, i.e. crystal structures. | |||||
| Objective | The lecture follows Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers. | |||||
| Content | Symmetry aspects of chemical bonding, point groups and representations for the deduction of molecular orbitals, energy assessment for molecules and solids, Sanderson formalism, derivation and understanding of band structures, densities of states, overlap populations, crystal symmetry, basic crystal structures and corresponding properties, visual representations of crystal structures. | |||||
| Lecture notes | see Moodle | |||||
| Literature | 1. I. Hargittai, M. Hargittai, "Symmetry through the Eyes of a Chemist", Plenum Press, 1995; 2. R. Hoffmann, "Solids and Surfaces", VCH 1988; 3. U. Müller, "Anorganische Strukturchemie", 6. Auflage, Vieweg + Teubner 2008 | |||||
| Prerequisites / Notice | Requirements: Inorganic Chemistry I | |||||
| 529-0222-00L | Organic Chemistry II | O | 3 credits | 2V + 1U | B. Morandi | |
| Abstract | This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. The basics or retro- and forward synthesis are also introduced. | |||||
| Objective | Goals of this course include a deeper understanding of basic organic reactions and mechanisms as well as advanced transformations. Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, are introduced, with an emphasis on their catalytic cycles and elementary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines. | |||||
| Content | Redox neutral reactions and rearrangements, advanced transformations of functional groups and reaction mechanisms, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reactions. | |||||
| Lecture notes | The lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link: https://morandi.ethz.ch/education.html | |||||
| Literature | Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012. | |||||
| 529-0431-00L | Physical Chemistry III: Molecular Quantum Mechanics  | O | 4 credits | 4G | F. Merkt | |
| Abstract | Postulates of quantum mechanics, operator algebra, Schrödinger's equation, state functions and expectation values, matrix representation of operators, particle in a box, tunneling, harmonic oscillator, molecular vibrations, angular momentum and spin, generalised Pauli principle, perturbation theory, electronic structure of atoms and molecules, Born-Oppenheimer approximation. | |||||
| Objective | This is an introductory course in quantum mechanics. The course starts with an overview of the fundamental concepts of quantum mechanics and introduces the mathematical formalism. The postulates and theorems of quantum mechanics are discussed in the context of experimental and numerical determination of physical quantities. The course develops the tools necessary for the understanding and calculation of elementary quantum phenomena in atoms and molecules. | |||||
| Content | Postulates and theorems of quantum mechanics: operator algebra, Schrödinger's equation, state functions and expectation values. Linear motions: free particles, particle in a box, quantum mechanical tunneling, the harmonic oscillator and molecular vibrations. Angular momentum: electronic spin and orbital motion, molecular rotations. Electronic structure of atoms and molecules: the Pauli principle, angular momentum coupling, the Born-Oppenheimer approximation. Variational principle and perturbation theory. Discussion of bigger systems (solids, nano-structures). | |||||
| Lecture notes | A script written in German will be available. The script is, however, no replacement for personal notes during the lecture and does not cover all aspects discussed. | |||||
| 529-0058-00L | Analytical Chemistry II | O | 3 credits | 3G | D. Günther, D. Bleiner, T. Bucheli, M.‑O. Ebert, G. Schwarz | |
| Abstract | Enhanced knowledge about the elemental analysis and spectrocopical techniques with close relation to practical applications. This course is based on the knowledge from analytical chemistry I. Separation methods are included. | |||||
| Objective | Use and applications of the elemental analysis and spectroscopical knowledge to solve relevant analytical problems. | |||||
| Content | Combined application of spectroscopic methods for structure determination, and practical application of element analysis. More complex NMR methods: recording techniques, application of exchange phenomena, double resonance, spin-lattice relaxation, nuclear Overhauser effect, applications of experimental 2d and multipulse NMR spectroscopy, shift reagents. Application of chromatographic and electrophoretic separation methods: basics, working technique, quality assessment of a separation method, van-Deemter equation, gas chromatography, liquid chromatography (HPLC, ion chromatography, gel permeation, packing materials, gradient elution, retention index), electrophoresis, electroosmotic flow, zone electrophoresis, capillary electrophoresis, isoelectrical focussing, electrochromatography, 2d gel electrophoresis, SDS-PAGE, field flow fractionation, enhanced knowledge in atomic absorption spectroscopy, atomic emission spectroscopy, X-ray fluorescence spectroscopy, ICP-OES, ICP-MS. | |||||
| Lecture notes | Script will be available | |||||
| Literature | Literature will be within the script. | |||||
| Prerequisites / Notice | Exercises for spectra interpretation are part of the lecture. In addition the lecture 529-0289-00 "Instrumentalanalyse organischer Verbindungen" (4th semester) is recommended. Prerequisite: 529-0051-00 "Analytische Chemie I" (3rd semester) | |||||
| 529-0625-00L | Chemical Engineering | O | 3 credits | 3G | W. J. Stark | |
| Abstract | Chemical Engineering provides an introduction to production and process design. Beyond different types and operation of chemical or bio-reactors, issues of scaling, new synthesis methods and problems of industrial production are addressed. An introduction in heterogeneous catalysis and transport of impulse, mass and energy connect the new concepts to the basic education in chemistry and biology. | |||||
| Objective | Intended for chemists, chemical engineers, biochemists and biologists, the course Chemical and Bioengineering 4th semester addresses the basics of production and process design. Starting with different reactors, process steps and unit operations in production, the industrial scale usage of chemicals and reagents are discussed and further illustrated by examples. Material and energy balances and the concept of selectivity are used to broaden the students view on the complexity of production and show how modern engineering can contribute to an environmentally sustainable production. In the second part of the lecture, reactors, single cells or living matter are discussed in terms of transport properties. Beyond metabolism or chemical processes, transport of impulse, mass and energy heavily influence chemical and biological processes. They are introduced simultaneously and provide a basis for the understanding of flow, diffusion and heat transport. Dimensionless numbers are used to implement transport properties in unit operations and process design. An introduction to heterogeneous catalysis connects the acquired concepts to chemistry and biology and shows how powerful new processes arise from combining molecular understanding and transport. | |||||
| Content | Elements of chemical transformations: preparation of reactants, reaction process, product work-up and recycling, product purification; continuous, semibatch and batch processes; material balances: chemical reactors and separation processes, multiple systems and multistage systems; energy balances: chemical reactors and separation processes, enthalpy changes, coupled material and energy balances; multiple reactions: optimisation of reactor performance, yield and selectivity; mass transport and chemical reaction: mixing effects in homogeneous and heterogeneous systems, diffusion and reaction in porous materials; heat exchange and chemical reaction: adiabatic reactors, optimum operating conditions for exothermic and endothermic equilibrium reactions, thermal runaway, reactor size and scale up. | |||||
| Lecture notes | Supporting material to the course is available on the homepage www.fml.ethz.ch | |||||
| Literature | Literature and text books are announced at the beginning of the course. | |||||
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