Suchergebnis: Katalogdaten im Frühjahrssemester 2021

Biologie Bachelor Information
Bachelor-Studium (Studienreglement 2013)
3. Studienjahr, 6. Semester
Blockkurse
Anmeldung zu Blockkursen muss zwingend über die website Link
Anmeldung möglich von 19.12.2020 bis 09.01.2021

Bitte die ETH Aufnahmekriterien für die Aufnahme von Studierenden der ETH in ETH Blockkurse auf der Blockkurs-Anmeldeseite unter "Zuteilung" beachten.
Blockkurse im 3. Semesterviertel
Von 20.04.2021 bis 12.05.2021
NummerTitelTypECTSUmfangDozierende
551-0362-00LMolecular Health: Biomedical Analysis of the Extracellular Interactome Belegung eingeschränkt - Details anzeigen
Number of participants limited to 12.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
W6 KP7PB. Wollscheid, E. Tschudy-Milani
KurzbeschreibungIn this course you will learn to measure, integrate, analyze and validate the cellular surfaceome as a complex information gateway connecting the intracellular to the extracellular interactome. You will apply next generation technologies at the interface of biology, chemistry, medicine and bioinformatics to establish the surfaceome proteotype and its signaling interaction networks.
Lernziel"If a cell surface molecule such as the B cell receptor would have the size of a human being, then the cell surface of a B cell would have roughly the size of three times NYC Central Park." How many people/proteins/proteoforms reside in this space ("Surfaceome")? Similar to humans, proteins don't act alone. Function is encoded in dynamic protein-protein interactions. How are these proteoforms organized in signaling islands/networks in order to fulfill specific cellular functions ("Interactome")? What are the ligands interacting with the surfaceome to communicate information from other cells & tissues in the body? What goes wrong in these signaling islands if we get sick?

In this course you will learn to measure, integrate, analyze and validate the cellular surfaceome and its signaling islands as a complex information gateway connecting the intracellular to the extracellular interactome. You will apply next generation technologies at the interface of biology, chemistry, medicine and bioinformatics to generate unprecedented data to establish the surfaceome proteotype and its signaling interaction networks. This digital proteotype data layer provides the basis for generating qualitative and quantitative surfaceome models explaining how molecular nanoscale organization influences cellular signaling and biological function.
Inhalt"If a cell surface molecule such as the B cell receptor would have the size of a human being, then the cell surface of a B cell would have roughly the size of three times NYC Central Park." How many people/proteins/proteoforms reside in this space ("Surfaceome")? Similar to humans, proteins don't act alone. Function is encoded in dynamic protein-protein interactions. How are these proteoforms organized in signaling islands/networks in order to fulfill specific cellular functions ("Interactome")? What are the ligands interacting with the surfaceome to communicate information from other cells & tissues in the body? What goes wrong in these signaling islands if we get sick?

In this course you will learn to measure, integrate, analyze and validate the cellular surfaceome and its signaling islands as a complex information gateway connecting the intracellular to the extracellular interactome. You will apply next generation technologies at the interface of biology, chemistry, medicine and bioinformatics to generate unprecedented data to establish the surfaceome proteotype and its signaling interaction networks. This digital proteotype data layer provides the basis for generating qualitative and quantitative surfaceome models explaining how molecular nanoscale organization influences cellular signaling and biological function.
LiteraturD. Bausch-Fluck, E. S. Milani, B. Wollscheid, Surfaceome nanoscale organization and extracellular interaction networks, Curr. Opin. Chem. Biol. 48, 26–33 (2019).

Link
Voraussetzungen / BesonderesThis course requires a basic knowledge in mass spectrometry based proteomics and experience in computational data processing using R or MatLab. Ideally this course should be combined with course 551-0352-00L "Introduction to Mass Spectrometry-based Proteomics".
529-0810-01LOrganische Chemie II (für D-BIOL) Belegung eingeschränkt - Details anzeigen
-Wo immer möglich müssen die Distanzregeln eingehalten werden.
-Alle Studierende müssen während des gesamten Kurses Masken tragen. Bitte Reserve-Masken bereithalten. Zugelassen sind Hygienemasken (IIR) oder Schutzmasken (FFP2) ohne Ventil. Community Masken (Stoffmasken) sind nicht erlaubt.
-Die Installation und Aktivierung der Schweizer Covid-App ist sehr zu empfehlen.
-Alle zusätzlichen Regeln für einzelne Kurse müssen eingehalten werden -Studierende, die COVID-19-Symptome aufweisen, dürfen die ETH-Gebäude nicht betreten und müssen den verantwortlichen Kursleiter informieren.
W12 KP4PC. Thilgen
KurzbeschreibungBearbeiten eines organisch-synthetischen Teilprojekts aus der aktuellen Forschung einer Gruppe des Laboratoriums für Organische Chemie unter der Anleitung von Doktorierenden.
LernzielErlernen von Planung und Durchführung anspruchsvoller Mehrstufensynthesen unter Einbezug moderner Methoden; vertieftes Verständnis organisch-chemischer Reaktionen durch Experimente; Entwickeln eines organisch-synthetischen Forschungsprojekts; akkurates Protokollieren, Verfassen eines Berichts im Stil einer Veröffentlichung und Präsentieren der Ergebnisse in Form eines Kurzvortrags.
InhaltBearbeiten eines organisch-synthetischen Teilprojekts aus der aktuellen Forschung einer Gruppe des Laboratoriums für Organische Chemie unter der Anleitung von Doktorierenden.
SkriptKein Skript.
LiteraturKeine Pflichtliteratur. Literatur wird von den betreuenden Doktorierenden angegeben bzw. zur Verfügung gestellt.
Voraussetzungen / BesonderesVoraussetzungen: bestandenes Praktikum Organische Chemie I (529-0229-00); bestandene Sessionsprüfung Organische Chemie I (529-0221-00 bzw. 529-1011-00) / Organische Chemie II (529-0222-00 bzw. 529-1012-00). Die Zahl der Teilnehmenden ist auf 12 beschränkt.
551-0344-00LPlant Microbiomes Belegung eingeschränkt - Details anzeigen
Number of participants limited to 8.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
W6 KP7PJ. Vorholt-Zambelli
KurzbeschreibungLaboratory course. Research projects in the field of plant microbiomes are conducted in small groups. They address open questions related to plant microbiomes and include microbial community assembly, microbial interactions, plant protection and plant immunity.
LernzielIntroduction to relevant subjects of the biology of plant-associated microorganisms. Training in practical work in a research laboratory. Exposure to current research topics in the field of plant microbiomes. Scientific writing in form of a research report.
InhaltResearch project in plant microbiomes. The techniques used will depend on the project, e.g. PCR, cloning, microbial community analysis via next-generation sequencing, plant inoculation experiments, phenotypic analyses, fluorescence microscopy, gene expression, metabolomics, bioinformatics
Skriptnone
LiteraturWill be provided for each of the projects at the beginning of the course.
551-1556-00LMacromolecular Structure Determination Using Modern Methods Belegung eingeschränkt - Details anzeigen
Number of participants limited to 11 in the 3rd semester quarter of the spring semester

Number of participants limited to 12 in the 4th semester quarter of the spring semester

The block course will only take place with a minimum of 4 participants.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
W6 KP7PK. Locher, R. Irobalieva, J. Kowal, G. Schertler
KurzbeschreibungThis course will expose the students to two prominent techniques for high-resolution structural characterization of biological macromolecules. The students will have the opportunity to get hands-on experience in either cryo-electron microscopy (ETH) or X-ray crystallography (PSI).
LernzielThe goal of this course is to introduce the students to the principles of high-resolution structure determination. Students will conduct hands-on experiments and use computational techniques for data processing.
InhaltAt the ETH the students will prepare and vitrify a protein and then image it on a cryo-TEM. Next, the students will process the data and build an atomic model into the EM map.

At the PSI the students will purify and crystallize a membrane protein, collect X-ray diffraction data using synchrotron X-ray source or with cryo-EM, analyze and build an atomic model into a density map. They will refine this model and interpret and illustrate the determined structure. The course work is trying to present insights in the use of structural information. The course also includes a demonstration of the Synchrotron capabilities at the Paul Scherrer Institute (SLS).
Voraussetzungen / BesonderesThe students will be split into two groups for the practical part of the work: One group will work at ETH Hönggerberg, the other at the Paul Scherrer Institute (PSI) at Villigen. All students will spend one full day at the PSI for a tour of the facilities, including a visit of the synchrotron beam lines of the Swiss Light Source SLS.

The students joining the ETH Hönggerberg group will spend the majority of the time on data processing and are therefore expected to have some basic knowledge of bash terminal commands. Basic physics, optics and linear algebra knowledge is also helpful. By the end of the course, the students will be expected to understand concepts such as the difference between Fourier and real space, image formation, contrast transfer, fast Fourier transfer and Fourier shell correlation.
551-1312-00LRNA-Biology II Belegung eingeschränkt - Details anzeigen
Number of participants limited to 14.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
W6 KP7PS. Jonas, F. Allain, J. Corn, U. Kutay, O. Voinnet
KurzbeschreibungIntroduction to the diversity of current RNA-research at all levels from structural biology to systems biology using mainly model systems like S. cerevisiae (yeast), mammalian cells.
LernzielThe students will obtain an overview about the diversity of current RNA-research. They will learn to design experiments and use techniques necessary to analyze different aspects of RNA biology. Through lectures and literature seminars, they will learn about the burning questions of RNA research and discuss approaches to address these questions experimentally. In practical lab projects the students will work in one of the participating laboratories. Finally, they will learn how to present and discuss their data in an appropriate manner. Student assessment is a graded semester performance based on individual performance in the laboratory, the written exam and the project presentation.
SkriptRelevant material from the lectures will be made available during the course via the corresponding Moodle page.
LiteraturDocumentation and recommended literature will be provided at the beginning and during the course.
551-1300-00LCause and Consequences of Unstable Genomes Belegung eingeschränkt - Details anzeigen
Number of participants limited to 14.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
W6 KP7PM. Jagannathan, Y. Barral, C. Beyer, K. Bomblies, R. Kroschewski, G. Neurohr
KurzbeschreibungThe course will introduce students to key concepts and laboratory research within the broad field of "Genome stability".
LernzielStudents will learn to design, apply and evaluate current research strategies in a wide range of modern research areas encompassing the broad field of "Genome stability".
InhaltThe course will consist of lectures, practical laboratory work in small groups, informal progress report sessions, and the presentation of laboratory work. Lectures will expose students to key concepts and techniques in the field. Students will team into small groups and work in one laboratory for the duration of the course. Students will meet regularly for informal "progress report" discussions of their projects. Student performance will be assessed based on the quality of their practical work, a written exam on frontal lecture material, and a presentation of their practical work.
LiteraturDocumentation and recommended literature in the form of review articles and selected primary literature will be provided during the course.
Voraussetzungen / BesonderesThis course will be taught in English.
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