Search result: Catalogue data in Spring Semester 2020
|Elective Major Subject Areas|
|Elective Major: Biochemistry|
| Elective Compulsory Concept Courses|
See D-BIOL Master Studies Guide
|551-0326-00L||Cell Biology||W||6 credits||4V||S. Werner, M. Bordoli, W. Kovacs, M. Schäfer, U. Suter, A. Wutz|
|Abstract||This Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.|
|Objective||-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.|
-To convey knowledge about neuron-glia interactions in health and disease.
- To provide information on different types of stem cells and their function in health and disease
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
|551-0307-01L||Molecular and Structural Biology II: Molecular Machines and Cellular Assemblies|
D-BIOL students are obliged to take part I and part II as a two-semester course.
|W||3 credits||2V||N. Ban, F. Allain, S. Jonas, M. Pilhofer|
|Abstract||This course on advanced topics in Molecular Biology and Biochemistry will cover the structure and function of cellular assemblies. General topics in basic biochemistry will be further developed with examples of the function of large cellular machines involved in DNA packaging, translation, virus architecture, RNA processing, cell-cell interactions, and the molecular basis of CRISPER systems.|
|Objective||Students will gain a deep understanding of large cellular assemblies and the structure-function relationships governing their function in fundamental cellular processes. The lectures throughout the course will be complemented by exercises and discussions of original research examples to provide students with a deeper understanding of the subjects and to encourage active student participation.|
|Content||Advanced class covering the state of the research in structural molecular biology of basic cellular processes with emphasis on the function of large cellular assemblies.|
|Lecture notes||Updated handouts will be provided during the class.|
|Literature||The lecture will be based on the latest literature. Additional suggested|
Branden, C., and J. Tooze, Introduction to Protein Structure, 2nd ed.
(1995). Garland, New York.
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