Search result: Catalogue data in Spring Semester 2020
DAS Preparation for the Swiss Federal Examination in Pharmacy  | ||||||
 First Series of Courses (Group A) | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|---|
| 535-0522-00L | Pharmacology and Toxicology II | O | 2 credits | 2V | U. Quitterer | |
| Abstract | The two-semester lecture course will provide a basic understanding of mechanisms of drug action, pharmacological properties and therapeutic uses of important classes of drugs. The lectures are intended for students of pharmacy and health sciences. | |||||
| Learning objective | The lectures will provide a comprehensive survey of pharmacology and toxicology. Special emphasis is placed on the interrelationship between pharmacological, pathophysiological and clinical aspects. | |||||
| Content | Topics include disease-relevant macroscopic, microscopic, pathobiochemical and functional disturbances of specific organs and organ systems. The lectures integrate disease pathology with mechanisms of drug action, usage, pharmacokinetics, side effects, toxicology, contraindications and dosage of relevant drug classes. Basic principles of clinical pharmacology and pharmacotherapy will be covered. | |||||
| Lecture notes | A script is provided for each lecture, which contains major contents of the lecture and defines exam-relevant topics. The scripts do not replace the lectures. | |||||
| Literature | Klaus Aktories, Ulrich Förstermann, Franz Hofmann, Klaus Starke. Allgemeine und spezielle Pharmakologie und Toxikologie. 12. Auflage, 1146 Seiten 2017 Urban & Fischer Verlag/Elsevier GmbH, ISBN-10: 3437425250; ISBN-13: 978-3437425257 The classic textbook on pharmacology: Goodman & Gilman`s The Pharmacological Basis of Therapeutics. Laurence Brunton, Björn Knollmann, Randa Hilal-Dandan 13th edition, 1440 pages 2017; McGraw - Hill Education ISBN-10: 1259584739 ISBN-13: 978-1259584732 | |||||
| Prerequisites / Notice | Abschluss Grundstudium. Gleichzeitiger oder vorgängiger Besuch des Seminars 535-0523-00 Aktuelle Themen aus Pharmakologie und Toxikologie ist dringend empfohlen. | |||||
| 535-0523-00L | Current topics in Pharmacology and Toxicology  | O | 1 credit | 1S | U. Quitterer | |
| Abstract | The practical course complements the lectures on Pharmacology and Toxicology. The course is held in parallel to the lecture course during the spring semester. | |||||
| Learning objective | Gain in-depth knowledge of pharmacology and toxicology, and understand basic principles of pharmacotherapy. | |||||
| Content | The course presents selected topics of pharmacology and toxicology to understand principles of pharmacotherapy of major diseases. In frame of the course, students perform exercises. | |||||
| Lecture notes | A script is provided for each course. The script defines relevant knowledge for the exam in Pharmacology and Toxicology I/II. | |||||
| Literature | Klaus Aktories, Ulrich Förstermann, Franz Hofmann, Klaus Starke. Allgemeine und spezielle Pharmakologie und Toxikologie. 12. Auflage, 1146 Seiten 2017 Urban & Fischer Verlag/Elsevier GmbH, ISBN-10: 3437425250; ISBN-13: 978-3437425257 The classic textbook on pharmacology: Goodman & Gilman`s The Pharmacological Basis of Therapeutics. Laurence Brunton, Björn Knollmann, Randa Hilal-Dandan 13th edition, 1440 pages 2017; McGraw - Hill Education ISBN-10: 1259584739 ISBN-13: 978-1259584732 | |||||
| Prerequisites / Notice | Voraussetzungen: Abschluss Grundstudium | |||||
| 535-0241-03L | Biopharmacy | O | 3 credits | 3V | S.‑D. Krämer | |
| Abstract | Introduction to the Basics in Biopharmacy. Pharmacokinetic processes (absorption, distribution, metabolism and excretion, ADME), which determine the fate of a drug in the body. Knowledge of the most important pharmacokinetic parameters. Interpretation of concentration-time-profiles of drugs. Pharmacokinetic profiling of drugs in view of therapy optimization and analysis of interaction potential. | |||||
| Learning objective | Introduction to the Basics in Biopharmacy. Pharmacokinetic processes (absorption, distribution, metabolism and excretion, ADME), which determine the fate of a drug in the body. Knowledge of the most important pharmacokinetic parameters. Interpretation of concentration-time-profiles of drugs. Pharmacokinetic profiling of drugs in view of therapy optimization and analysis of interaction potential. | |||||
| Content | Introduction to pharmacokinetics; definition of the most important pharmacokinetic parameters and their calculation from clinical data (compartment model, statistical model); kinetics of absorption (absorption profiles); distribution of drugs and role of protein binding; kinetics of elimination: excretion and biotransformation (physiological model); pharmacokinetic profiling of drugs for therapy optimization and for the analysis of the interaction potential; dosage regimen design. | |||||
| Literature | P. Langguth, G. Fricker, H. Wunderli-Allenspach "Biopharmazie", Wiley-VCH Verlag, Weinheim, 2004. | |||||
| 535-0422-00L | Galenical Pharmacy II | O | 2 credits | 2G | J.‑C. Leroux, E. Giger | |
| Abstract | Continues Galenical Pharmacy I. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Suppositories. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration. | |||||
| Learning objective | Introduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. In continuation of Galenical Pharmacy I. The students dispose of knowledge of properties, function, quality and application of dosage forms. The following topics will be covered: Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Suppositories. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration. Formulation of biotechnology products. | |||||
| Content | Overview of important fundamentals, principles and technologies for the development and manufacturing of solid dosage forms and drug delivery systems. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration. | |||||
| Lecture notes | Scripts, documentations to the lectures and additional supporting materials can be either downloaded via the indicated link to the course , or they will be directly provided at each lecture. | |||||
| Literature | A.T. Florence - An introduction to clinical pharmaceutics. Pharmaceutical Press, London 2010. L.V. Allen, N.G. Popovich, H.C. Ansel, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 10th Ed, Lippincott Williams & Wilkins, Baltimore 2014. L. Felton, Remington - Essentials of Pharmaceutics, Pharmaceutical Press, London, 2013. M.E. Aulton. Pharmaceutics - The design and manufacture of medicines. 5th Ed. Elsevier, Philadelphia, 2017. Sinko P.J., Martin's Physical Pharmacy and Pharmaceutical Sciences, 7th ed, Wolters Kluwer, Philadelphia, 2017. | |||||
| Prerequisites / Notice | Prior attendance of Galenical Pharmacy I is recommended. | |||||
| 535-0135-00L | Clinical Chemistry I | O | 1 credit | 1V | M. Hersberger | |
| Abstract | Introduction into the fundamentals of laboratory diagnostics and an overview on the laboratory parameters used in the context of inflammation, lipid metabolism, myocardial infarction, diabetes, kidney function, urinary analysis, liver function, blood coagulation, blood counts, therapeutic drug monitoring and drugs of abuse screening. | |||||
| Learning objective | Overview on the possibilities and limitations in clinical laboratory diagnostics offered in pharmacies. Indications and methods of often used analyses are known. | |||||
| Content | Introduction into medical laboratory diagnostics: immunochemical methods, diagnostics of inflammation, acute myocardial infarction, lipid metabolism, diabetes, kidney function and urinary diagnostics, blood coagulation, blood count, therapeutic drug monitoring, drugs of abuse screening, common diagnostics of liver diseases, point-of-care diagnostics. | |||||
| Lecture notes | Documentation will be available before the lectures electronically. | |||||
| Literature | - Jürgen Hallbach, Klinische Chemie und Hämatologie für den Einstieg, Thieme Verlag - Harald Renz, Praktische Labordiagnostik, de Gruyter Verlag - Walter Guder, Das Laborbuch für Klinik und Praxis, Elsevier Verlag | |||||
| 535-0391-00L | Pathobiology | O | 4 credits | 3G | M. Detmar, V. I. Otto | |
| Abstract | Pathobiology describes the mechanisms underlying a disease and its clinical manifestations. An overview over important diseases of different organ systems and their symptoms will be given. How the discussed diseases can be recognized based on symptoms and diagnostic tests will be practiced based on case studies. | |||||
| Learning objective | Understanding of the molecular mechanisms that link the cause of a disease to its clinical manifestation. Knowing the most important diseases and their symptoms. First abilities to recognize and distinguish between different diseases based on case studies. | |||||
| Content | Lecture Topics: 1. Introduction and General Pathology 2. Diseases of Blood Cells 3. Kidney Diseases 4. Cardiovascular Diseases 5. Lung Diseases 6. Gastrointestinal Diseases 7. Disorders of the Endocrine System 8. Metabolic Disorders 9. Skin Diseases 10. Diseases of the Reproductive Organs 11. Diseases of the Bones and Joints 12. Disorders of the Central Nervous System 13. Disorders of Sensory Organs 14. Psychiatric Diseases Case studies referring to the diseases discussed in the course of the lectures will be solved and the solutions presented by the students. | |||||
| Lecture notes | Will be available at the following website: myStudies | |||||
| Literature | Kumar Vinay ; Abbas Abul K. ; Fausto Nelson ; Aster Jon C, Robbins and Cotran Pathologic Basis of Disease, 9th ed., Saunders Elsevier, Philadelphia 2015 Mitchell Richard N. ; Kumar Vinay ; Abbas Abul K. ; Fausto Nelson ; Aster Jon C., Pocket Companion to Robbins and Cotran Pathologic Basis of Disease, 9th ed., Elsevier Saunders, Philadelphia 2017 Tischendorf Frank W. (Hrsg.), Blickdiagnostik : Compact-Atlas der klinischen Inspektion und Differenzialdiagnostik, 5. Aufl., Schattauer Verlag, Stuttgart 2017 | |||||
| Prerequisites / Notice | Requirements: Completion of Basic Studies | |||||
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