Suchergebnis: Katalogdaten im Herbstsemester 2019

Doktorat Departement Biologie Information
Mehr Informationen unter: Link
Lehrangebot Doktorat und Postdoktorat
NummerTitelTypECTSUmfangDozierende
376-1791-00LIntroductory Course in Neuroscience I (University of Zurich) Information
Der Kurs muss direkt an der UZH belegt werden.
UZH Modulkürzel: SPV0Y005

Beachten Sie die Einschreibungstermine an der UZH: Link
W2 KP2VW. Knecht, Uni-Dozierende
KurzbeschreibungThe course gives an introduction to human and comparative neuroanatomy, molecular, cellular and systems neuroscience.
LernzielThe course gives an introduction to the development and anatomical structure of nervous systems. Furthermore, it discusses the basics of cellular neurophysiology and neuropharmacology. Finally, the nervous system is described on a system level.
Inhalt1) Human Neuroanatomy I&II
2) Comparative Neuroanatomy
3) Building a central nervous system I,II
4) Synapses I,II
5) Glia and more
6) Excitability
7) Circuits underlying Emotion
8) Visual System
9) Auditory & Vestibular System
10) Somatosensory and Motor Systems
11) Learning in artificial and biological neural networks
Voraussetzungen / BesonderesFor doctoral students of the Neuroscience Center Zurich (ZNZ).
151-0255-00LEnergy Conversion and Transport in BiosystemsW4 KP2V + 1UA. Ferrari
KurzbeschreibungTheorie und Anwendung von Thermodynamik und Energieerhaltung in biologischen Systemen mit Schwerpunkt auf Zellebene.
LernzielTheorie und Anwendung von Energieerhaltung auf Zellebene. Verständnis für die grundlegenden Stofftransport-Kreisläufe in menschlichen Zellen und die Mechanismen, welche diese Kreisläufe beeinflussen. Parallelen zu anderen Gebieten im Ingenieurswesen erkennen. Wärme- und Massentransport Prozesse in der Zelle, Kraft Entwicklung der Zelle, und die Verbindung zu modernen biomedizinischen Technologien.
InhaltMassentransportmodelle für den Transport von chemischen Spezies in der menschlichen Zelle. Organisation und Funktion der Zellmembran und des Zytoskeletts. Die Rolle molekularer Motoren in der Kraftentwicklung der Zelle und deren Funktion in der Fortbewegung der Zelle. Beschreibung der Funktionsweise dieser Systeme sowie der experimentellen Analyse und Simulationen um sie besser zu verstehen. Einführung in den Zell-Metabolismus, Zell-Energietransport und die Zelluläre Thermodynamik.
SkriptKursmaterial wird in Form von Hand-outs verteilt.
LiteraturNotizen sowie Referenzen aus der Vorlesung.
151-0927-00LRate-Controlled Separations in Fine ChemistryW6 KP3V + 1UM. Mazzotti
KurzbeschreibungDie Studenten sollen einen vertieften Einblick in die Grundlagen der Trennverfahren erhalten, die in modernen Life Sciences Prozessen - spez. Feinchemie und Biotechnologie - zur Anwendung kommen.
LernzielDie Studenten sollen einen vertieften Einblick in die Grundlagen der Trennverfahren erhalten, die in modernen Life Sciences Prozessen - spez. Feinchemie und Biotechnologie - zur Anwendung kommen.
InhaltThe class covers separation techniques that are central in the purification and downstream processing of chemicals and bio-pharmaceuticals. Examples from both areas illustrate the utility of the methods: 1) Liquid-liquid extraction; 2) Adsorption and chromatography; 3) Membrane processes; 4) Crystallization and precipitation.
SkriptBeilagen in der Vorlesung
LiteraturBücher werden in der Vorlesung besprochen
Voraussetzungen / BesonderesBesonderes: Teile der Vorlesung werden in Englisch gehalten.

Voraussetzungen: Thermische Verfahrenstechnik I (151-0926-00) und Mathematische Methoden in den Chemieingenieurwissenschaften (151-0940-00)
401-0649-00LApplied Statistical RegressionW5 KP2V + 1UM. Dettling
KurzbeschreibungThis course offers a practically oriented introduction into regression modeling methods. The basic concepts and some mathematical background are included, with the emphasis lying in learning "good practice" that can be applied in every student's own projects and daily work life. A special focus will be laid in the use of the statistical software package R for regression analysis.
LernzielThe students acquire advanced practical skills in linear regression analysis and are also familiar with its extensions to generalized linear modeling.
InhaltThe course starts with the basics of linear modeling, and then proceeds to parameter estimation, tests, confidence intervals, residual analysis, model choice, and prediction. More rarely touched but practically relevant topics that will be covered include variable transformations, multicollinearity problems and model interpretation, as well as general modeling strategies.

The last third of the course is dedicated to an introduction to generalized linear models: this includes the generalized additive model, logistic regression for binary response variables, binomial regression for grouped data and poisson regression for count data.
SkriptA script will be available.
LiteraturFaraway (2005): Linear Models with R
Faraway (2006): Extending the Linear Model with R
Draper & Smith (1998): Applied Regression Analysis
Fox (2008): Applied Regression Analysis and GLMs
Montgomery et al. (2006): Introduction to Linear Regression Analysis
Voraussetzungen / BesonderesThe exercises, but also the classes will be based on procedures from the freely available, open-source statistical software package R, for which an introduction will be held.

In the Mathematics Bachelor and Master programmes, the two course units 401-0649-00L "Applied Statistical Regression" and 401-3622-00L "Statistical Modelling" are mutually exclusive. Registration for the examination of one of these two course units is only allowed if you have not registered for the examination of the other course unit.
551-1619-00LStrukturbiologieW1 KP1KR. Glockshuber, F. Allain, N. Ban, K. Locher, M. Pilhofer, E. Weber-Ban, K. Wüthrich
KurzbeschreibungDer Kurs besteht aus Forschungs-Seminaren aus dem Gebiet der Strukturbiologie, Biochemie und Biophysik, die von Wissenschaftlern des Nationalen Schwerpunktprogramms (NCCR) Strukturbiologie gehalten werden, als auch von externen Sprechern. Informationen über die einzelnen Vorträge:
Link
Link
LernzielZiel des Kurses ist es, Doktorierenden und Postdoktoranden einen breiten Überblick über die jüngsten Entwicklungen auf dem Gebiet der Strukturbiologie, Biochemie und Biophysik zu vermitteln
851-0180-00LResearch Ethics Belegung eingeschränkt - Details anzeigen
Number of participants limited to 40

Particularly suitable for students of D-BIOL, D-CHAB, D-HEST
W2 KP2GG. Achermann
KurzbeschreibungThis course enables students to:
• Improve their moral reasoning skills (e.g. identify, construct and evaluate moral arguments);
• Identify and describe leading normative approaches and concepts for research involving animals and human subjects;
• Analyse the theoretical foundations and disputes on moral issues related to research involving animals and human subjects.
LernzielParticipants of the course Research Ethics will
• Develop an understanding of the role of certain moral concepts, principles and normative theories related to scientific research;
• Improve their moral reasoning skills (such as identifying and evaluating reasons, conclusions, assumptions, analogies, concepts and principles), and their ability to use these skills in assessing other people’s arguments, making decisions and constructing their own reasoning to the kinds of ethical problems a scientist is likely to encounter;
• Deepen their understanding of the debates on certain central moral issues in research, e.g. the use of animals in biomedical research.
InhaltI. Introduction to Moral Reasoning
1. Ethics - the basics
- What is ethics? What ethics is not...
- Identification of moral issues (awareness): what constitutes an ethical question? Distinguishing ethical questions from other kinds of questions;
- Values (personal, cultural & ethical) & principles for ethical conduct in research;
- Descriptive and prescriptive ethics
- Ethical universalism, ethical relativism and cultural relativism
- What is research ethics and why is it important?

2. Normative Ethics
- Overview on important theories for research ethics: virtue theories, duty-based theories (rights theory, categorical imperative, prima facie duties), consequentialist theories, other theories;
- The plurality of ethical theories, moral pluralism and its consequences;

3. Arguments
- Why arguments? What is a good argument? The structure of (moral) arguments;
- Deductive and inductive arguments; Validity and soundness; strength and cogency;
- Assessing moral arguments

II. Research involving animals
1. The moral status of animals: moral considerability (morally relevant features), moral significance;
2. Representative views (indirect theories, direct but unequal theories, and moral equality theories) on the moral status of animals and resulting standpoints on the use of animals in biomedical research
- The 3 R's (replacement, reduction, refinement);
- Public policy in the context of moral disagreement
- The concept of dignity and the dignity of living beings in the Swiss constitution;
- The weighing/evaluation of interests: the procedure and criticism, the value of basic research and related problems in the weighing of interests;

III. Research involving human subjects
- History of research involving human subjects
- Basic ethical principles – the Belmont report
- Selection of study participants. The concept of vulnerability
- Assessment of risks and benefits of a research project
- Research ethics committees
- Information and consent; confidentiality and anonymity;
- Research projects involving biological material and health related data
SkriptCourse material (handouts, case studies, exercises, surveys and papers) will be available during the lectures and on the course homepage.
Voraussetzungen / BesonderesWhat are the requirements?
First and foremost your strong willingness to seriously achieve the main learning outcomes as indicated in the Course Catalogue (specific learning outcomes for each module will be provided at the beginning of the course). For successfully completing the course Research Ethics, the following commitment is absolutely necessary (but not sufficient) (observed success factors for many years!):
1. Your regular presence is absolutely required (so please no double, parallel enrollment for courses taking place at the identical time!) connected with your active participation during class, e.g. taking notes, contributing to discussions (in group as well as in plenary class), solving exercises.
2. Having the willingness and availability of the necessary time for regularly preparing the class (at least 1 hour per week, probably even more…).
401-5640-00LZüKoSt: Seminar on Applied Statistics Information E-0 KP1KM. Kalisch, A. Bandeira, P. L. Bühlmann, R. Furrer, L. Held, T. Hothorn, M. H. Maathuis, M. Mächler, L. Meier, M. Robinson, C. Strobl, C. Uhler, S. van de Geer
KurzbeschreibungEtwa 5 Vorträge zur angewandten Statistik.
LernzielKennenlernen von statistischen Methoden in ihrer Anwendung in verschiedenen Anwendungsgebieten.
InhaltIn etwa 5 Einzelvorträgen pro Semester werden Methoden der Statistik einzeln oder überblicksartig vorgestellt, oder es werden Probleme und Problemtypen aus einzelnen Anwendungsgebieten besprochen.
Voraussetzungen / BesonderesDies ist keine Vorlesung. Es wird keine Prüfung durchgeführt, und es werden keine Kreditpunkte vergeben.
Nach besonderem Programm:
Link
Lehrsprache ist Englisch oder Deutsch je nach ReferentIn.
551-1109-00LSeminars in MicrobiologyE-0 KP2KM. Aebi, H.‑M. Fischer, W.‑D. Hardt, M. Künzler, J. Piel, S. Sunagawa, J. Vorholt-Zambelli
KurzbeschreibungSeminars by invited speakers covering selected microbiology themes.
LernzielDiscussion of selected microbiology themes presented by invited speakers.
551-0030-01LDoktorarbeitE-0 KPProfessor/innen
KurzbeschreibungDoktorarbeit
Lernziel
401-0620-00LStatistischer BeratungsdienstE-0 KP0.1KM. Kalisch, L. Meier
KurzbeschreibungDer statistische Beratungsdienst steht allen Angehörigen der ETH und in begrenztem Masse auch Aussenstehenden offen.
LernzielBeratung bei der statistischen Auswertung von wissenschaftlichen Daten.
InhaltStudierende und Forschende werden bei der Auswertung wissenschaftlicher Daten individuell beraten, insbesondere auch bei Bachelor-, Master- und Doktorarbeiten. Es ist sehr empfehlenswert, den Beratungsdienst nicht erst kurz vor dem Abschluss einer Arbeit aufzusuchen, sondern bereits bei der Planung einer Studie.
Voraussetzungen / BesonderesDies ist keine Vorlesung sondern ein Beratungsangebot. Es wird keine Prüfung durchgeführt, und es werden keine Kreditpunkte vergeben.

Anmeldungen richtet man an Link Tel. 044 632 2223. Siehe auch Link

Voraussetzungen: Kenntnis der Grundbegriffe der Statistik ist sehr erwünscht.
551-0512-00LCurrent Topics in Molecular and Cellular Neurobiology Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
Number of participants limited to 8.
W2 KP1SU. Suter
KurzbeschreibungThe course is a literature seminar or "journal club". Each Friday a student, or a member of the Suter Lab in the Institute of Molecular Health Sciences, will present a paper from the recent literature.
LernzielThe course introduces you to recent developments in the fields of cellular and molecular neurobiology. It also supports you to develop your skills in critically reading the scientific literature. You should be able to grasp what the authors wanted to learn i.e. their goals, why the authors chose the experimental approach they used, the strengths and weaknesses of the experiments and the data presented, and how the work fits into the wider literature in the field. You will present one paper yourself, which provides you with practice in public speaking.
InhaltYou will present one paper yourself. Give an introduction to the field of the paper, then show and comment on the main results (all the papers we present are available online, so you can show original figures with a beamer). Finish with a summary of the main points and a discussion of their significance.
You are expected to take part in the discussion and to ask questions. To prepare for this you should read all the papers beforehand (they will be announced a week in advance of the presentation).
SkriptPresentations will be made available after the seminars.
Voraussetzungen / BesonderesYou must attend at least 80% of the journal clubs, and give a presentation of your own. At the end of the semester there will be a 30 minute oral exam on the material presented during the semester. The grade will be based on the exam (45%), your presentation (45%), and a contribution based on your active participation in discussion of other presentations (10%).
551-0737-00LEcology and Evolution: Interaction Seminar Information Belegung eingeschränkt - Details anzeigen W2 KP2SS. Bonhoeffer
KurzbeschreibungInteraction seminar. Student-mediated presentations, guests and discussions on current themes in ecology, evolutionary and population biology.
LernzielGetting familiar with scientific arguments and discussions. Overview of current research topics. Making contacts with fellow students in other groups.
InhaltScientific talks and discussions on changing subjects.
SkriptNone
LiteraturNone
Voraussetzungen / BesonderesFor information, location and details: Link
551-0509-00LCurrent Immunological Research in ZürichE-0 KP1KR. Spörri, M. Detmar, C. Halin Winter, W.‑D. Hardt, M. Kopf, S. R. Leibundgut, A. Oxenius, Uni-Dozierende
KurzbeschreibungThis monthly meeting is a platform for Zurich-based immunology research groups to present and discuss their ongoing research projects. At each meeting three PhD students or Postdocs from the participating research groups present an ongoing research project in a 30 min seminar followed by a plenary discussion.
LernzielThe aim of this monthly meeting is to provide further education for master and doctoral students as well as Postdocs in diverse topics of immunology and to give an insight in the related research. Furthermore, this platform fosters the establishment of science- and technology-based interactions between the participating research groups.
InhaltPresentation and discussion of current research projects carried out by various immunology-oriented research groups in Zurich.
Skriptnone
551-1615-00LNMR Methods for Studies of Biological Macromolecules
Prerequisites: Basic knowledge in biological NMR spectroscopy.
W1 KP2SA. D. Gossert
KurzbeschreibungSeminar series on technical aspects of high resolution nuclear magnetic resonance (NMR) spectroscopy with biological macromolecules.
This seminar series is targeted at Master students and PhD students conducting research projects in the field of biomolecular NMR in solution.
LernzielIntroduction and discussion of advanced methods for recording and analysis of NMR data with biological macromolecules.
InhaltSeminar series on technical aspects of high-resolution nuclear magnetic resonance (NMR) spectroscopy with biological macromolecules.
This seminar series is targeted at Master students and PhD students conducting research projects in the field of biomolecular NMR in solution.
551-1409-00LRNA Biology Lecture Series II: Non-coding RNAs: Biology and TherapeuticsW4 KP2VJ. Hall, M. Stoffel, weitere Dozierende
KurzbeschreibungThis course covers aspects of RNA biology related to the functions of non-coding RNAs as well as their use as drugs to treat diseases.
LernzielThe students should get familiar with the wide array of roles, which non-coding RNAs play in cellular functions.
InhaltMicro RNAs; computational approaches to miRNAs; micro RNA function in metabolism; viruses and viral RNAs; nucleic acid-based drugs; ncRNA-mediated genome regulation; epigenetic programming of genome remodelling in ciliates; telomerase and telomeres; tRNA biology. Link
Voraussetzungen / BesonderesBasic knowledge of cell and molecular biology.
551-1407-00LRNA Biology Lecture Series I: Transcription & Processing & Translation
Findet dieses Semester nicht statt.
W4 KP2VF. Allain, N. Ban, U. Kutay, weitere Dozierende
KurzbeschreibungThis course covers aspects of RNA biology related to gene expression at the posttranscriptional level. These include RNA transcription, processing, alternative splicing, editing, export and translation.
LernzielThe students should obtain an understanding of these processes, which are at work during gene expression.
InhaltTranscription & 3'end formation ; splicing, alternative splicing, RNA editing; the ribosome & translation, translation regulation, RNP biogenesis & nuclear export, mRNA surveillance & mRNA turnover; signal transduction & RNA.
Voraussetzungen / BesonderesBasic knowledge of cell and molecular biology.
551-1423-00LCurrent Topics in Metabolism and Disease Belegung eingeschränkt - Details anzeigen
Number of participants limited to 8.
W2 KP1SM. Stoffel, E. Araldi, I. Guccini
KurzbeschreibungThe course is a literature seminar or "journal club". Each Friday a student, or a member of the Stoffel Lab in the Institute of Molecular Health Sciences, will present a comprehensive presentation of a recent paper published in a top ranking international peer reviewed journal that relates to metabolism and disease.
LernzielThe course introduces the students to recent developments in the fields of metabolism and disease. It also supports the development of analytical skills, including critical reading of scientific literature, being able to present and critically discuss scientific experiments, point out technical limitations, and placing recent discoveries in the broader context of biology, physiology and medicine. The student should be able to grasp what the authors wanted to learn i.e. their hypothesis and their goals, why the authors chose the experimental approach and methods used, the strengths and weaknesses of the experiments, the quality of the data presented, the conclusions drawn, and how the work fits into the wider literature in the field. Furthermore, the student should discuss alternative approaches and future experiments. Each student will present one paper during the course, which provides him/her with practice in public speaking.
InhaltEach student will present at least once during the semester. The presentation includes an introduction to the field of the paper, a critical description of the main results, a summary of the main points and a discussion of their significance.
Every participant is expected to take part in the discussion and to ask questions. At each meeting, all students are expected to read and prepare the paper beforehand. Each paper presented will be announced one week in advance of the presentation.
SkriptPresentations will be made available after the seminars.
LiteraturStudents will be guided to choose their papers base on recent literature published less than 1 year prior in a relevant journal.
701-0015-00LTransdisciplinary Research: Challenges of Interdisciplinarity and Stakeholder Engagement Belegung eingeschränkt - Details anzeigen
Number of participants limited to 20.
Priority is given to PhD students D-USYS.

All participants will be on the waiting list at first. Enrollment is possible until September 25th. The waiting list is active until September 27th. All students will be informed on September 27th, if they can participate in the lecture.
The lecture takes place if a minimum of 12 students register for it.
W2 KP2SM. Stauffacher, C. E. Pohl
KurzbeschreibungThis seminar is designed for PhD students and PostDoc researchers involved in inter- or transdisciplinary research. It addresses and discusses challenges of this kind of research using scientific literature presenting case studies, concepts, theories, methods and by testing practical tools. It concludes with a 10-step approach to make participants' research projects more societally relevant.
LernzielParticipants know specific challenges of inter- and transdisciplinary research and can address them by applying practical tools. They can tackle questions like: how to integrate knowledge from different disciplines, how to engage with societal actors, how to secure broader impact of research? They learn to critically reflect their own research project in its societal context and on their role as scientists.
InhaltThe seminar covers the following topics:
(1) Theories and concepts of inter- and transdisciplinary research
(2) The specific challenges of inter- and transdisciplinary research
(3) Collaborating between different disciplines
(4) Engaging with stakeholders
(5) 10 steps to make participants' research projects more societally relevant
Throughout the whole course, scientific literature will be read and discussed as well as practical tools explored in class to address concrete challenges.
LiteraturLiterature will be made available to the participants.
The following open access article builds a core element of the course:
Pohl, C., Krütli, P., & Stauffacher, M. (2017). Ten Reflective Steps for Rendering Research Societally Relevant. GAIA 26(1), 43-51 doi: 10.14512/gaia.26.1.10
available at: Link
Further, this collection of tools will be used
Link
Voraussetzungen / BesonderesParticipation in the course requires participants to be working on their own research project.
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