Suchergebnis: Katalogdaten im Frühjahrssemester 2018

Biologie Master Information
Wahlvertiefungen
Wahlvertiefung: Zellbiologie
Wahlpflicht Konzeptkurse
Siehe D-BIOL Master-Wegleitung
NummerTitelTypECTSUmfangDozierende
551-0324-00LSystems BiologyW6 KP4VR. Aebersold, B. Christen, M. Claassen, U. Sauer
KurzbeschreibungIntroduction to experimental and computational methods of systems biology. By using baker’s yeast as a thread through the series, we focus on global methods for analysis of and interference with biological functions. Illustrative applications to other organisms will highlight medical and biotechnological aspects.
Lernziel- obtain an overview of global analytical methods
- obtain an overview of computational methods in systems biology
- understand the concepts of systems biology
InhaltOverview of global analytical methods (e.g. DNA arrays, proteomics, metabolomics, fluxes etc), global interference methods (siRNA, mutant libraries, synthetic lethality etc.) and imaging methods. Introduction to mass spectrometry and proteomics. Concepts of metabolism in microbes and higher cells. Systems biology of developmental processes. Concepts of mathematical modeling and applications of computational systems biology.
Skriptno script
LiteraturThe course is not taught by a particular book, but some books are suggested for further reading:

- Systems biology in Practice by Klipp, Herwig, Kowald, Wierling und Lehrach. Wiley-VCH 2005
551-0320-00LCellular Biochemistry (Part II)W3 KP2VY. Barral, R. Kroschewski, A. E. Smith
KurzbeschreibungThis course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes.
LernzielThe full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry.
The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection.
InhaltSpatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection.
LiteraturRecommended supplementary literature (review articles and selected primary literature) will be provided during the course.
Voraussetzungen / BesonderesTo attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English.
In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform.
551-0318-00LImmunology IIW3 KP2VM. Kopf, S. R. Leibundgut, A. Oxenius, E. Slack, weitere Dozierende
KurzbeschreibungEinführung in die zellulären und molekularen Grundlagen des Immunsystems und die Immunreaktionen gegen verschiedene Pathogene, Tumore, Transplantate, und körpereigene Strukturen (Autoimmunität)
LernzielDie Vorlesung soll ein grundlegendes Verständnis vermitteln über:
- die Interaktion der verschiedenen Immunzellen auf zellulärer und molekularer Ebene?
- Erkennung und Abwehr ausgewählter Viren, Bakterien, und Parasiten.
- Abwehr von Tumoren.
- Mechanismen der Toleranz für körpereigene Moleküle.
- Funktion des Immunsystems im Darm und warum kommensale Bakterien keine Immunantwort auslösen.
- Immunpathologie und entzündliche Erkrankungen.
InhaltZiel dieser Vorlesung ist das Verständnis:
> Wie Pathogene vom unspezifischen Immunystem erkannt werden
> Wie Pathogene vom Immunsystem bekämpft werden
> Immunantworten der Haut, Lung, und Darms
> Tumorimmunologie
> Migration von Immunzellen
> Toleranz und Autoimmunität
> das Gedächtnis von T Zellen
SkriptDie Vorlesungsunterlagen der Dozenten sind verfügbar in Moodle
LiteraturEmpfohlen: Kuby Immunology (Freeman)
376-0209-00LMolecular Disease MechanismsW6 KP4VC. Wolfrum, H. Gahlon, M. Kopf, D. Peleg-Raibstein
KurzbeschreibungIn this course the mechanisms of disease development will be studied. Main topics will be:

1. Influence of environmental factors with an emphasis on inflammation and the immune response.
2. Mechanisms underlying disease progression in metabolic disorders, integrating genetic and environmental factors.
3. Mechanisms underlying disease progression in cancer, integrating genetic and environment
LernzielTo understand the mechanisms governing disease development with a special emphasis on genetic and environmental associated components
SkriptAll information can be found at:

Link

The enrollment key will be provided by email
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