Suchergebnis: Katalogdaten im Frühjahrssemester 2018
MAS in Medizinphysik  | ||||||
 Fachrichtung: Allg. Medizinphysik und Biomedizinisches Ingenieurwesen | ||||||
| Vertiefung Radiation Therapy | ||||||
| Kernfächer | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|---|
| 227-0968-00L | Monte Carlo in Medical Physics | W | 4 KP | 3G | M. Stampanoni, M. K. Fix | |
| Kurzbeschreibung | Introduction in basics of Monte Carlo simulations in the field of medical radiation physics. General recipe for Monte Carlo simulations in medical physics from code selection to fine-tuning the implementation. Characterization of radiation by means of Monte Carlo simulations. | |||||
| Lernziel | Understanding the concept of the Monte Carlo method. Getting familiar with the Monte Carlo technique, knowing different codes and several applications of this method. Learn how to use Monte Carlo in the field of applied medical radiation physics. Understand the usage of Monte Carlo to characterize the physical behaviour of ionizing radiation in medical physics. Share the enthusiasm about the potential of the Monte Carlo technique and its usefulness in an interdisciplinary environment. | |||||
| Inhalt | The lecture provides the basic principles of the Monte Carlo method in medical radiation physics. Some fundamental concepts on applications of ionizing radiation in clinical medical physics will be reviewed. Several techniques in order to increase the simulation efficiency of Monte Carlo will be discussed. A general recipe for performing Monte Carlo simulations will be compiled. This recipe will be demonstrated for typical clinical devices generating ionizing radiation, which will help to understand implementation of a Monte Carlo model. Next, more patient related effects including the estimation of the dose distribution in the patient, patient movements and imaging of the patient's anatomy. A further part of the lecture covers the simulation of radioactive sources as well as heavy ion treatment modalities. The field of verification and quality assurance procedures from the perspective of Monte Carlo simulations will be discussed. To complete the course potential future applications of Monte Carlo methods in the evolving field of treating patients with ionizing radiation. | |||||
| Skript | A script will be provided. | |||||
| 402-0342-00L | Medical Physics II | W | 6 KP | 2V + 1U | P. Manser | |
| Kurzbeschreibung | Applications of ionizing radiation in medicine such as radiation therapy, nuclear medicine and radiation diagnostics. Theory of dosimetry based on cavity theory and clinical consequences. Fundamentals of dose calculation, optimization and evaluation. Concepts of external beam radiation therapy and brachytherapy. Recent and future developments: IMRT, IGRT, SRS/SBRT, particle therapy. | |||||
| Lernziel | Getting familiar with the different medical applications of ionizing radiation in the fields of radiation therapy, nuclear medicine, and radiation diagnostics. Dealing with concepts such as external beam radiation therapy as well as brachytherapy for the treatment of cancer patients. Understanding the fundamental cavity theory for dose measurements and its consequences on clinical practice. Understanding different delivery techniques such as IMRT, IGRT, SRS/SBRT, brachytherapy, particle therapy using protons, heavy ions or neutrons. Understanding the principles of dose calculation, optimization and evaluation for radiation therapy, nuclear medicine and radiation diagnostic applications. Finally, the lecture aims to demonstrate that medical physics is a fascinating and evolving discipline where physics can directly be used for the benefits of patients and the society. | |||||
| Inhalt | In this lecture, the use of ionizing radiation in different clinical applications is discussed. Primarily, we will concentrate on radiation therapy and will cover applications such as external beam radiotherapy with photons and electrons, intensity modulated radiotherapy (IMRT), image guided radiotherapy (IGRT), stereotactic radiotherapy and radiosurgery, brachytherapy, particle therapy using protons, heavy ions or neutrons. In addition, dosimetric methods based on cavity theory are reviewed and principles of treatment planning (dose calculation, optimization and evaluation) are discussed. Next to these topics, applications in nuclear medicine and radiation diagnostics are explained with the clear focus on dosimetric concepts and behaviour. | |||||
| Skript | A script will be provided. | |||||
| Voraussetzungen / Besonderes | It is recommended that the students have taken the lecture Medical Physics I in advance. | |||||
| Praktika | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
| 465-0420-00L | Strahlenschutz-Sachverstand  Nur für MAS in Medizinphysik | W | 4 KP | 6G | externe Veranstalter | |
| Kurzbeschreibung | Der Kurs umfasst alle Inhalte in Theorie und Praxis, die für eine anerkannte Ausbildung zu Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktivem Material in einem Arbeitsbereich B/C notwendig sind. Nach erfolgreich abgeschlossener Prüfung wird ein vom BAG anerkanntes Zertifikat ausgestellt. Dieses erlaubt auch den Einsatz als Strahlenschutz-Beauftragte im Aufsichtsbereich des ENSI. | |||||
| Lernziel | Die Teilnehmenden erwerben in der Ausbildung die Kompetenzen, Fähigkeiten und Kenntnisse, um die Funktion des Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktiven Material im Arbeitsbereich B/C anerkannt gemäss Strahlenschutz Ausbildungsverordnung (814.501.261) ausüben zu dürfen. | |||||
| Inhalt | - Grundkenntnisse der Strahlenphysik und der Strahlenbiologie - Dosisabschätzung bei interner und externer Bestrahlung - Kenntnis der für den Umgang mit offenen und geschlossenen Strahlenquellen massgeblichen Gesetzen und Verordnungen - Erkennen und abschätzen von Gefährdungspotenzialen - Festlegen von Strahlenschutz-Betriebsvorschriften, Sicherheitsplänen sowie baulicher, organisatorischer und operationeller Massnahmen - Kenntnis und Anwendung von Messgeräten - Planung und Durchführung der Personen- und Arbeitsplatzüberwachung | |||||
| 465-0800-00L | Practical Work Nur für MAS in Medizinphysik | W | 4 KP | externe Veranstalter | ||
| Kurzbeschreibung | The practical work is designed to train the students in the solution of a specific problem and provides insights in the field of the selected MAS specialization. Tutors propose the subject of the project, the project plan, and the roadmap together with the student, as well as monitor the overall execution. | |||||
| Lernziel | The practical work is aimed at training the student’s capability to apply and connect specific skills acquired during the MAS specialization program towards the solution of a focused problem. | |||||
| Wahlfächer | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
| 227-0390-00L | Elements of Microscopy | W | 4 KP | 3G | M. Stampanoni, G. Csúcs, A. Sologubenko | |
| Kurzbeschreibung | The lecture reviews the basics of microscopy by discussing wave propagation, diffraction phenomena and aberrations. It gives the basics of light microscopy, introducing fluorescence, wide-field, confocal and multiphoton imaging. It further covers 3D electron microscopy and 3D X-ray tomographic micro and nanoimaging. | |||||
| Lernziel | Solid introduction to the basics of microscopy, either with visible light, electrons or X-rays. | |||||
| Inhalt | It would be impossible to imagine any scientific activities without the help of microscopy. Nowadays, scientists can count on very powerful instruments that allow investigating sample down to the atomic level. The lecture includes a general introduction to the principles of microscopy, from wave physics to image formation. It provides the physical and engineering basics to understand visible light, electron and X-ray microscopy. During selected exercises in the lab, several sophisticated instrument will be explained and their capabilities demonstrated. | |||||
| Literatur | Available Online. | |||||
| 227-0946-00L | Molecular Imaging - Basic Principles and Biomedical Applications | W | 2 KP | 2V | M. Rudin | |
| Kurzbeschreibung | Concept: What is molecular imaging. Discussion/comparison of the various imaging modalities used in molecular imaging. Design of target specific probes: specificity, delivery, amplification strategies. Biomedical Applications. | |||||
| Lernziel | Molecular Imaging is a rapidly emerging discipline that translates concepts developed in molecular biology and cellular imaging to in vivo imaging in animals and ultimatly in humans. Molecular imaging techniques allow the study of molecular events in the full biological context of an intact organism and will therefore become an indispensable tool for biomedical research. | |||||
| Inhalt | Concept: What is molecular imaging. Discussion/comparison of the various imaging modalities used in molecular imaging. Design of target specific probes: specificity, delivery, amplification strategies. Biomedical Applications. | |||||
| 227-0948-00L | Magnetic Resonance Imaging in Medicine | W | 4 KP | 3G | S. Kozerke, M. Weiger Senften | |
| Kurzbeschreibung | Introduction to magnetic resonance imaging and spectroscopy, encoding and contrast mechanisms and their application in medicine. | |||||
| Lernziel | Understand the basic principles of signal generation, image encoding and decoding, contrast manipulation and the application thereof to assess anatomical and functional information in-vivo. | |||||
| Inhalt | Introduction to magnetic resonance imaging including basic phenomena of nuclear magnetic resonance; 2- and 3-dimensional imaging procedures; fast and parallel imaging techniques; image reconstruction; pulse sequences and image contrast manipulation; equipment; advanced techniques for identifying activated brain areas; perfusion and flow; diffusion tensor imaging and fiber tracking; contrast agents; localized magnetic resonance spectroscopy and spectroscopic imaging; diagnostic applications and applications in research. | |||||
| Skript | D. Meier, P. Boesiger, S. Kozerke Magnetic Resonance Imaging and Spectroscopy | |||||
| 376-1984-00L | Lasers in Medicine | W | 3 KP | 3G | M. Frenz | |
| Kurzbeschreibung | Fragen wie "Was ist ein Laser, wie funktioniert er und was macht ihn so interessant für die Medizin?", aber auch "Wie breitet sich Licht im Gewebe aus und welche Wechselwirkungen treten dabei auf?" sollen beantwortet werden. Speziell wird auf therapeutische, diagnostische und bildgebende Anwendungen anhand von ausgewählten Beispielen eingegangen. | |||||
| Lernziel | Einführung in die für medizinische Anwendungen relevanten Lasertechniken. Vermittlung der physikalischen Grundlagen der Laser-Gewebe-Wechselwirkung mit dem Ziel, den Einfluss der unterschiedlichen Bestrahlungsparameter auf den Gewebeeffekt zu verstehen. Grundlagen der diagnostischen Laseranwendungen und der Lasersicherheit. | |||||
| Inhalt | Die Anwendung des Lasers in der Medizin gewinnt zunehmend dort an Bedeutung, wo seine speziellen Eigenschaften gezielt zur berührungslosen, selektiven und spezifischen Wirkung auf Weich- und Hartgewebe für minimal invasive Therapieformen oder zur Eröffnung neuer therapeutischer und diagnostischer Methoden eingesetzt werden können. Grundlegende Arbeiten zum Verständnis der Lichtausbreitung im Gewebe (Absorptions-, Reflexions- und Transmissionsvermögen) und die unterschiedlichen Formen der Wechselwirkung (photochemische, thermische, ablative und optomechanische Wirkung) werden eingehend behandelt. Speziell wird auf den Einfluss der Wellenlänge und der Bestrahlungszeit auf den Wechselwirkungsmechanismus eingegangen. Die unterschiedlichen medizinisch genutzten Lasertypen und Strahlführungssysteme werden hinsichtlich ihres Einsatzes im Bereich der Medizin anhand ausgesuchter Anwendungsbeispiele diskutiert. Neben den therapeutischen Wirkungen wird auf den Einsatz des Lasers in der medizinischen Diagnostik (z.B. Tumor-Fluoreszenzdiagnostik, Bildgebung) eingegangen. Die beim Einsatz des Lasers in der Medizin erforderlichen Schutzmassnahmen werden diskutiert. | |||||
| Skript | wird im Internet bereitgestellt | |||||
| Literatur | - M. Born, E. Wolf, "Principles of Optics", Pergamon Press - B.E.A. Saleh, M.C. Teich, "Fundamentals of Photonics", John Wiley and Sons, Inc. - A.E. Siegman, "Lasers", University Science Books - O. Svelto, "Principles of Lasers", Plenum Press - J. Eichler, T. Seiler, "Lasertechnik in der Medizin", Springer Verlag - M.H. Niemz, "Laser-Tissue Interaction", Springer Verlag - A.J. Welch, M.J.C. van Gemert, "Optical-thermal response of laser-irradiated tissue", Plenum Press | |||||
| 402-0343-00L | Physics Against Cancer: The Physics of Imaging and Treating Cancer | W | 6 KP | 2V + 1U | A. J. Lomax, U. Schneider | |
| Kurzbeschreibung | Radiotherapy is a rapidly developing and technology driven medical discipline that is heavily dependent on physics and engineering. In this lecture series, we will review and describe some of the current developments in radiotherapy, particularly from the physics and technological view point, and will indicate in which direction future research in radiotherapy will lie. | |||||
| Lernziel | Radiotherapy is a rapidly developing and technology driven medical discipline that is heavily dependent on physics and engineering. In the last few years, a multitude of new techniques, equipment and technology have been introduced, all with the primary aim of more accurately targeting and treating cancerous tissues, leading to a precise, predictable and effective therapy technique. In this lecture series, we will review and describe some of the current developments in radiotherapy, particularly from the physics and technological view point, and will indicate in which direction future research in radiotherapy will lie. Our ultimate aim is to provide the student with a taste for the critical role that physics plays in this rapidly evolving discipline and to show that there is much interesting physics still to be done. | |||||
| Inhalt | The lecture series will begin with a short introduction to radiotherapy and an overview of the lecture series (lecture 1). Lecture 2 will cover the medical imaging as applied to radiotherapy, without which it would be impossible to identify or accurately calculate the deposition of radiation in the patient. This will be followed by a detailed description of the treatment planning process, whereby the distribution of deposited energy within the tumour and patient can be accurately calculated, and the optimal treatment defined (lecture 3). Lecture 4 will follow on with this theme, but concentrating on the more theoretical and mathematical techniques that can be used to evaluate different treatments, using mathematically based biological models for predicting the outcome of treatments. The role of physics modeling, in order to accurately calculate the dose deposited from radiation in the patient, will be examined in lecture 5, together with a review of mathematical tools that can be used to optimize patient treatments. Lecture 6 will investigate a rather different issue, that is the standardization of data sets for radiotherapy and the importance of medical data bases in modern therapy. In lecture 7 we will look in some detail at one of the most advanced radiotherapy delivery techniques, namely Intensity Modulated Radiotherapy (IMRT). In lecture 8, the two topics of imaging and therapy will be somewhat combined, when we will describe the role of imaging in the daily set-up and assessment of patients. Lecture 9 follows up on this theme, in which a major problem of radiotherapy, namely organ motion and changes in patient and tumour geometry during therapy, will be addressed, together with methods for dealing with such problems. Finally, in lectures 10-11, we will describe in some of the multitude of different delivery techniques that are now available, including particle based therapy, rotational (tomo) therapy approaches and robot assisted radiotherapy. In the final lecture, we will provide an overview of the likely avenues of research in the next 5-10 years in radiotherapy. The course will be rounded-off with an opportunity to visit a modern radiotherapy unit, in order to see some of the techniques and delivery methods described in the course in action. | |||||
| Voraussetzungen / Besonderes | Although this course is seen as being complimentary to the Medical Physics I and II course of Dr Manser, no previous knowledge of radiotherapy is necessarily expected or required for interested students who have not attended the other two courses. | |||||
| 465-0968-00L | Medizinphysik in der Praxis | W | 2 KP | 2V | P. Manser, Referent/innen | |
| Kurzbeschreibung | Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen. Ein wichtiger Bestandteil ist dabei, den Dialog zwischen den Studierenden und den Praktikern zu fördern und Kontakte zu schaffen. Hierzu berichten verschiedene Dozenten aus der ganzen Schweiz über ihre Arbeit als Medizinphysiker. | |||||
| Lernziel | Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen. | |||||
| 402-0787-00L | Therapeutic Applications of Particle Physics: Principles and Practice of Particle Therapy | W | 6 KP | 2V + 1U | A. J. Lomax | |
| Kurzbeschreibung | Physics and medical physics aspects of particle physics Subjects: Physics interactions and beam characteristics; medical accelerators; beam delivery; pencil beam scanning; dosimetry and QA; treatment planning; precision and uncertainties; in-vivo dose verification; proton therapy biology. | |||||
| Lernziel | The lecture series is focused on the physics and medical physics aspects of particle therapy. The radiotherapy of tumours using particles (particularly protons) is a rapidly expanding discipline, with many new proton and particle therapy facilities currently being planned and built throughout Europe. In this lecture series, we study in detail the physics background to particle therapy, starting from the fundamental physics interactions of particles with tissue, through to treatment delivery, treatment planning and in-vivo dose verification. The course is aimed at students with a good physics background and an interest in the application of physics to medicine. | |||||
| Voraussetzungen / Besonderes | The former title of this course was "Medical Imaging and Therapeutic Applications of Particle Physics". | |||||
| 227-0384-00L | Ultrasound Fundamentals, Imaging, and Medical Applications Number of participants limited to 25. | W | 4 KP | 3G | O. Göksel | |
| Kurzbeschreibung | Ultrasound is the only imaging modality that is nonionizing (safe), real-time, cost-effective, and portable, with many medical uses in diagnosis, intervention guidance, surgical navigation, and as a therapeutic option. In this course, we introduce conventional and prospective applications of ultrasound, starting with the fundamentals of ultrasound physics and imaging. | |||||
| Lernziel | Students can use the fundamentals of ultrasound, to analyze and evaluate ultrasound imaging techniques and applications, in particular in the field of medicine, as well as to design and implement basic applications. | |||||
| Inhalt | Ultrasound is used in wide range of products, from car parking sensors, to assessing fault lines in tram wheels. Medical imaging is the eye of the doctor into body; and ultrasound is the only imaging modality that is nonionizing (safe), real-time, cheap, and portable. Some of its medical uses include diagnosing breast and prostate cancer, guiding needle insertions/biopsies, screening for fetal anomalies, and monitoring cardiac arrhythmias. Ultrasound physically interacts with the tissue, and thus can also be used therapeutically, e.g., to deliver heat to treat tumors, break kidney stones, and targeted drug delivery. Recent years have seen several novel ultrasound techniques and applications – with many more waiting in the horizon to be discovered. This course covers ultrasonic equipment, physics of wave propagation, numerical methods for its simulation, image generation, beamforming (basic delay-and-sum and advanced methods), transducers (phased-, linear-, convex-arrays), near- and far-field effect, imaging modes (e.g., A-, M-, B-mode), Doppler and harmonic imaging, ultrasound signal processing techniques (e.g., filtering, time-gain-compensation, displacement tracking), image analysis techniques (deconvolution, real-time processing, tracking, segmentation, computer-assisted interventions), acoustic-radiation force, plane-wave imaging, contrast agents, micro-bubbles, elastography, biomechanical characterization, high-intensity focused ultrasound and therapy, lithotripsy, histotripsy, photo-acoustics phenomenon and opto-acoustic imaging, as well as sample non-medical applications such as the basics of non-destructive testing (NDT). | |||||
| Voraussetzungen / Besonderes | Hands-on exercises will help apply concepts learned in the module, and will involve a mix of designing, implementing, and evaluating in simulation environments, such as Matlab FieldII and k-Wave toolboxes. Prerequisites: Familiarity with basic numerical methods. Basic programming skills and experience in Matlab. | |||||
| Vertiefung Biomechanics | ||||||
| Kernfächer | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
| 376-1712-00L | Finite Element Analysis in Biomedical Engineering | W | 3 KP | 2V | S. J. Ferguson, B. Helgason | |
| Kurzbeschreibung | This course provides an introduction to finite element analysis, with a specific focus on problems and applications from biomedical engineering. | |||||
| Lernziel | Finite element analysis is a powerful simulation method for the (approximate) solution of boundary value problems. While its traditional roots are in the realm of structural engineering, the methods have found wide use in the biomedical engineering domain for the simulation of the mechanical response of the human body and medical devices. This course provides an introduction to finite element analysis, with a specific focus on problems and applications from biomedical engineering. This domain offers many unique challenges, including multi-scale problems, multi-physics simulation, complex and non-linear material behaviour, rate-dependent response, dynamic processes and fluid-solid interactions. Theories taught are reinforced through practical applications in self-programmed and commercial simulation software, using e.g. MATLAB, ANSYS, FEBIO. | |||||
| Inhalt | (Theory) The Finite Element and Finite Difference methods Gallerkin, weighted residuals, discretization (Theory) Mechanical analysis of structures Trusses, beams, solids and shells, DOFs, hand calculations of simple FE problems, underlying PDEs (Application) Mechanical analysis of structures Truss systems, beam systems, 2D solids, meshing, organ level analysis of bones (Theory and Application) Mechanical analysis of structures Micro- and multi-scale analysis, voxel models, solver limitations, large scale solvers (Theory) Non-linear mechanical analysis of structures Large strain, Newton-Rhapson, plasticity (Application) Non-linear mechanical analysis of structures Plasticity (bone), hyperelasticity, viscoelasticity (Theory and Application) Contact analysis Friction, bonding, rough contact, implants, bone-cement composites, pushout tests (Theory) Flow in Porous Media Potential problems, Terzhagi's consolidation (Application) Flow in Porous Media Confined and unconfined compression of cartilage (Theory) Heat Transfer and Mass Transport Diffusion, conduction and convection, equivalency of equations (Application) Heat Transfer and Mass Transport Sequentially-coupled poroelastic and transport models for solute transport (Theory) Computational Biofluid Dynamics Newtonian vs. Non-Newtonian fluid, potential flow (Application) Computational Biofluid Dynamics Flow between micro-rough parallel plates | |||||
| Skript | Handouts consisting of (i) lecturers' script, (ii) selected excerpts from relevant textbooks, (iii) selected excerpts from theory manuals of commercial simulation software, (iv) relevant scientific publications. | |||||
| Voraussetzungen / Besonderes | Familiarity with basic numerical methods. Programming experience with MATLAB. | |||||
| 376-1397-00L | Orthopaedic Biomechanics | W | 4 KP | 3G | R. Müller, G. H. Van Lenthe | |
| Kurzbeschreibung | This course is aimed at studying the mechanical and structural engineering of the musculoskeletal system alongside the analysis and design of orthopaedic solutions to musculoskeletal failure. | |||||
| Lernziel | To apply engineering and design principles to orthopaedic biomechanics, to quantitatively assess the musculoskeletal system and model it, and to review rigid-body dynamics in an interesting context. | |||||
| Inhalt | Engineering principles are very important in the development and application of quantitative approaches in biology and medicine. This course includes a general introduction to structure and function of the musculoskeletal system: anatomy and physiology of musculoskeletal tissues and joints; biomechanical methods to assess and quantify tissues and large joint systems. These methods will also be applied to musculoskeletal failure, joint replacement and reconstruction; implants; biomaterials and tissue engineering. | |||||
| Skript | Stored on ILIAS. | |||||
| Literatur | Orthopaedic Biomechanics: Mechanics and Design in Musculoskeletal Systems Authors: Donald L. Bartel, Dwight T. Davy, Tony M. Keaveny Publisher: Prentice Hall; Copyright: 2007 ISBN-10: 0130089095; ISBN-13: 9780130089090 | |||||
| Voraussetzungen / Besonderes | Lectures will be given in English. | |||||
| 376-1392-00L | Mechanobiology: Implications for Development, Regeneration and Tissue Engineering | W | 3 KP | 2G | A. Ferrari, K. Würtz-Kozak, M. Zenobi-Wong | |
| Kurzbeschreibung | This course will emphasize the importance of mechanobiology to cell determination and behavior. Its importance to regenerative medicine and tissue engineering will also be addressed. Finally, this course will discuss how age and disease adversely alter major mechanosensitive developmental programs. | |||||
| Lernziel | This course is designed to illuminate the importance of mechanobiological processes to life as well as to teach good experimental strategies to investigate mechanobiological phenomena. | |||||
| Inhalt | Typically, cell differentiation is studied under static conditions (cells grown on rigid plastic tissue culture dishes in two-dimensions), an experimental approach that, while simplifying the requirements considerably, is short-sighted in scope. It is becoming increasingly apparent that many tissues modulate their developmental programs to specifically match the mechanical stresses that they will encounter in later life. Examples of known mechanosensitive developmental programs include all forms of myogenesis (cardiac, skeletal and smooth muscles), osteogenesis (bones), chondrogenesis (cartilage), tendogenesis (tendons) and angiogenesis (blood vessels). Furthermore, general forms of cell behavior such as migration, extracellular matrix deposition, and complex tissue differentiation are also regulated by mechanical stimuli. Mechanically-regulated cellular processes are thus ubiquitous, ongoing and of great clinical importance. The overall importance of mechanobiology to humankind is illustrated by the fact that nearly 80% of our entire body mass arises from tissues originating from mechanosensitive developmental programs, principally bones and muscles. Unfortunately, our ability to regenerate mechanosensitive tissue diminishes in later life. As it is estimated that the fraction of the western world population over 65 years of age will double in the next 25 years, an urgency in the global biomedical arena exists to better understand how to optimize complex tissue development under physiologically-relevant mechanical environments for purposes of regenerative medicine and tissue engineering. | |||||
| Skript | n/a | |||||
| Literatur | Topical Scientific Manuscripts | |||||
| Praktika | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
| 465-0800-00L | Practical Work Nur für MAS in Medizinphysik | O | 4 KP | externe Veranstalter | ||
| Kurzbeschreibung | The practical work is designed to train the students in the solution of a specific problem and provides insights in the field of the selected MAS specialization. Tutors propose the subject of the project, the project plan, and the roadmap together with the student, as well as monitor the overall execution. | |||||
| Lernziel | The practical work is aimed at training the student’s capability to apply and connect specific skills acquired during the MAS specialization program towards the solution of a focused problem. | |||||
| Wahlfächer | ||||||
| Nummer | Titel | Typ | ECTS | Umfang | Dozierende | |
| 151-0630-00L | Nanorobotics | W | 4 KP | 2V + 1U | S. Pané Vidal | |
| Kurzbeschreibung | Nanorobotics is an interdisciplinary field that includes topics from nanotechnology and robotics. The aim of this course is to expose students to the fundamental and essential aspects of this emerging field. | |||||
| Lernziel | The aim of this course is to expose students to the fundamental and essential aspects of this emerging field. These topics include basic principles of nanorobotics, building parts for nanorobotic systems, powering and locomotion of nanorobots, manipulation, assembly and sensing using nanorobots, molecular motors, and nanorobotics for nanomedicine. | |||||
| 151-0980-00L | Biofluiddynamics | W | 4 KP | 2V + 1U | D. Obrist, P. Jenny | |
| Kurzbeschreibung | Introduction to the fluid dynamics of the human body and the modeling of physiological flow processes (biomedical fluid dynamics). | |||||
| Lernziel | A basic understanding of fluid dynamical processes in the human body. Knowledge of the basic concepts of fluid dynamics and the ability to apply these concepts appropriately. | |||||
| Inhalt | This lecture is an introduction to the fluid dynamics of the human body (biomedical fluid dynamics). For selected topics of human physiology, we introduce fundamental concepts of fluid dynamics (e.g., creeping flow, incompressible flow, flow in porous media, flow with particles, fluid-structure interaction) and use them to model physiological flow processes. The list of studied topics includes the cardiovascular system and related diseases, blood rheology, microcirculation, respiratory fluid dynamics and fluid dynamics of the inner ear. | |||||
| Skript | Lecture notes are provided electronically. | |||||
| Literatur | A list of books on selected topics of biofluiddynamics can be found on the course web page. | |||||
| 376-1150-00L | Clinical Challenges in Musculoskeletal Disorders | W | 2 KP | 2G | M. Leunig, S. J. Ferguson, A. Müller | |
| Kurzbeschreibung | This course reviews musculoskeletal disorders focusing on the clinical presentation, current treatment approaches and future challenges and opportunities to overcome failures. | |||||
| Lernziel | Appreciation of the surgical and technical challenges, and future perspectives offered through advances in surgical technique, new biomaterials and advanced medical device construction methods. | |||||
| Inhalt | Foot deformities, knee injuries, knee OA, hip disorders in the child and adolescent, hip OA, spine deformities, degenerative spine disease, shoulder in-stability, hand, rheumatoid diseases, neuromuscular diseases, sport injuries and prevention | |||||
| 376-1168-00L | Sports Biomechanics | W | 3 KP | 2V | S. Lorenzetti | |
| Kurzbeschreibung | Various types of sport are studied from a mechanical point of view. Of particular interest are the key parameters of a sport as well as the performance relevant indicators. | |||||
| Lernziel | The aim of this lecture is to enable the students to study a sport from a biomechanical viewpoint and to develop significant models for which evaluations of the limitations and verifications can be carried out. | |||||
| Inhalt | Sport biomechanics is concerned with the physical and mechanical basic principles of sports. The lecture requires an in-depth mechanical understanding on the side of the student. In this respect, the pre-attendance of the lectures Biomechanics II and Movement and Sports Biomechanics or an equivalent course is expected. The human body is treated as a mechanical system during sport. The interaction of the active and passive movements and outside influences is analysed. Using sports such as ski-jumping, cycling, or weight training, applicable models are created, analyzed and suitable measuring methods are introduced. In particular, the constraints as well as the limitations of the models are of great relevance. The students develop their own models for different sport types, critically discuss the advantages and disadvantages and evaluate applicable measurement methods. | |||||
| Skript | Handout will be distributed. | |||||
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