Search result: Catalogue data in Autumn Semester 2022
Biology Master | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Elective Major Subject Areas | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Elective Major: Biochemistry | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Elective Concept Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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551-0307-00L | Molecular and Structural Biology I: Protein Structure and Function D-BIOL students are obliged to take part I and part II (next semester) as a two-semester course | W | 3 credits | 2V | R. Glockshuber, K. Locher, E. Weber-Ban | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Biophysics of protein folding, membrane proteins and biophysics of membranes, enzymatic catalysis, catalytic RNA and RNAi, current topics in protein biophysics and structural biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Understanding of structure-function relationships in proteins and in protein folding, detailed understanding of biophysics and physical methods as well as modern methods for protein purification and microanalytics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Scripts on the individual topics can be found under http://www.mol.biol.ethz.ch/teaching. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | Basics: - Creighton, T.E., Proteins, Freeman, (1993) - Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman. - Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001). Current topics: References will be given during the lectures. . | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
551-0309-00L | Concepts in Modern Genetics Information for UZH students: Enrolment to this course unit only possible at ETH. No enrolment to module BIO348 at UZH. Please mind the ETH enrolment deadlines for UZH students: Link | W | 6 credits | 4V | Y. Barral, D. Bopp, A. Hajnal, O. Voinnet | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Concepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | This course focuses on the concepts of classical and modern genetics and genomics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | The topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Scripts and additional material will be provided during the semester. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
551-0313-00L | Microbiology (Part I) | W | 3 credits | 2V | W.‑D. Hardt, L. Eberl, B. Nguyen, J. Piel, M. Pilhofer, A. Vagstad | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Advanced lecture class providing a broad overview on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | This concept class will be based on common concepts and introduce to the enormous diversity among bacteria and archaea. It will cover the current research on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Advanced class covering the state of the research in bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Updated handouts will be provided during the class. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | Current literature references will be provided during the lectures. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | English The lecture "Grundlagen der Biologie II: Mikrobiologie" is the basis for this advanced lecture. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
551-0317-00L | Immunology I | W | 3 credits | 2V | M. Kopf, A. Oxenius | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Introduction into structural and functional aspects of the immune system. Basic knowledge of the mechanisms and the regulation of an immune response. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Introduction into structural and functional aspects of the immune system. Basic knowledge of the mechanisms and the regulation of an immune response. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | - Introduction and historical background - Innate and adaptive immunity, Cells and organs of the immune system - B cells and antibodies - Generation of diversity - Antigen presentation and Major Histoincompatibility (MHC) antigens - Thymus and T cell selection - Autoimmunity - Cytotoxic T cells and NK cells - Th1 and Th2 cells, regulatory T cells - Allergies - Hypersensitivities - Vaccines, immune-therapeutic interventions | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Electronic access to the documentation will be provided. The link can be found at "Lernmaterialien" | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | - Kuby, Immunology, 9th edition, Freemen + Co., New York, 2020 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | For D-BIOL students Immunology I (WS) and Immunology II (SS) will be examined as one learning entity in a "Sessionsprüfung". All other students write separate exams for Immunology I and Immunology II. All exams (combined exam Immunology I and II, individual exams) are offered in each exam session. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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529-0731-00L | Nucleic Acids and Carbohydrates Note for BSc Biology students: Only one of the two concept courses 529-0731-00 Nucleic Acids and Carbohydrates (autumn semester) or 529-0732-00 Proteins and Lipids (spring semester) can be counted for the Bachelor's degree. | W | 6 credits | 3G | K. Lang, P. A. Kast, S. J. Sturla, H. Wennemers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Structure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Structure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Structure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | No script; illustrations from the original literature relevant to the individual lectures will be provided weekly (typically as handouts downloadable from the Moodle server). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | Mainly based on original literature, a detailed list will be distributed during the lecture | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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