Search result: Catalogue data in Autumn Semester 2016

Health Sciences and Technology Bachelor Information
First Year Compulsory Subjects
First Year Examinations
NumberTitleTypeECTSHoursLecturers
551-0105-00LFundamentals of Biology IAO5 credits5GM. Aebi, E. Hafen
AbstractThe course provides an introduction to the basics of molecular- and cell biology and genetics.
ObjectiveIntroduction to modern biology and to principal biological concepts.
ContentThe course is divided into several chapters:
1. Basic principles of Evolution.
2. Chemistry of Life: Water; Carbon and molecular diversity; biomolecules
3. The cell: structure; membrane structure and function, cell cycle
4. Metabolism: Respiration; Photosynthesis; Fermentation
5. Inheritance: meiosis and sexual reproduction; Mendelian genetics, chromosomal basis of inheritance, molecular basis of inheritance, from gene to protein, regulation of gene expression; genomes and their evolution
Lecture notesNone.
LiteratureThe text-book "Biology" (Campbell, Reece) (10th edition) is the basis of the course.
The structure of the course is largely identical with that of the text-book.
Prerequisites / NoticeCertain sections of the text-book must be studied by self-instruction.
529-1001-01LGeneral Chemistry (for Biology/Pharmacy/HST) Information O4 credits4VW. Uhlig
AbstractThe lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes.
ObjectiveThe course is designed to provide an understanding of the basic principles and concepts of general and inorganic chemistry.
ContentThe lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes.
Literature- Charles E. Mortimer, Chemie - Das Basiswissen der Chemie. 12. Auflage, Georg Thieme Verlag Stuttgart, 2015.

Weiterführende Literatur:
Brown, LeMay, Bursten CHEMIE (deutsch)
Housecroft and Constable, CHEMISTRY (englisch)
Oxtoby, Gillis, Nachtrieb, MODERN CHEMISTRY (englisch)
529-1011-00LOrganic Chemistry I (for students of Biology, Pharmaceutical Sci., and Health Sci. & Tech.) Information O4 credits4GC. Thilgen
AbstractFundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
ObjectiveUnderstanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity.
ContentOrganic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
Lecture notesPrinted lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (Link).
LiteratureLecture notes are available.

As a supplement, a selection of textbooks is proposed during the course.
Prerequisites / NoticeThe course consists of plenary lectures (2 h per week) and problem-solving lessons (2 h per week, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I).
401-0291-00LMathematics IO6 credits4V + 2UE. W. Farkas
AbstractMathematics I/II is an introduction to one- and multidimensional calculus
and linear algebra emphasizing on applications.
ObjectiveStudents understand mathematics as a language for modeling and as a tool for
solving practical problems in natural sciences.
Students can analyze models, describe solutions qualitatively or calculate
them explicitly if need be. They can solve examples as well as their practical
applications manually and using computer algebra systems.
ContentEinführung in die Differential- und Integralrechnung von Funktionen einer Variablen und Anwendungen:

Funktionen. Stetigkeit. Differentialrechnung. Anwendungen der Differentialrechnung. Integralrechnung. Potenzreihen. Komplexe Zahlen. Matrizen.
LiteratureSiehe Lernmaterialien > Literatur

L. Papula, Mathematik für Ingenieure und Naturwissenschaftler, 11. Auflage, Vieweg und Teubner

Th. Wihler, Mathematik für Naturwissenschaften, 2 Bände:
Einführung in die Analysis, Einführung in die Lineare Algebra;
Haupt-Verlag Bern, UTB

Ch. Blatter, Lineare Algebra; VDF

H. H. Storrer: Einführung in die mathematische Behandlung der Naturwissenschaften I; Birkhäuser.
Prerequisites / NoticeDie Einschreibung in die Übungsgruppen erfolgt online.
Alle unter Link für die Vorlesung eingeschriebenen Studierenden können sich unter Link in eine Übungsgruppe einschreiben.

Der Zugang zu den Übungsserien erfolgt online.
Vorlesungsverzeichnis > Lernmaterialien > Material zur Vorlesung
252-0852-00LFoundations of Computer Science Information O4 credits2V + 2UL. E. Fässler, H.‑J. Böckenhauer, M. Dahinden, D. Komm, H. Lehner
AbstractStudents learn to apply selected concepts and tools from computer science for working on interdisciplinary projects.

The following topics are covered: modeling and simulations, introduction to programming, visualizing multi-dimensional data, introduction matrices, managing data with lists and tables and with relational databases, universal methods for algorithm design.
ObjectiveThe students learn to

- understand the role of computer science in science,
- to control computer and automate processes of problem solving by programming,
- choose and apply appropriate tools from computer science,
- process and analyze real-world data from their subject of study,
- handle the complexity of real-world data,
- know universal methods for algorithm design.
Content1. The role of computer science in science
2. Introduction to Programming with Python
3. Modeling and simulations
4. Introduction to Matrices with Matlab
5. Visualizing multidimensional data
6. Data management with lists and tables
7. Data management with a relational database
8. Universal methods for algorithm design
Lecture notesAll materials for the lecture are available at Link
Prerequisites / NoticeThis course is based on application-oriented learning. The students spend most of their time working through projects with data from natural science and discussing their results with teaching assistants. To learn the computer science basics there are electronic tutorials available.
376-0003-00LIntroduction to Health Sciences and Technology I Restricted registration - show details O4 credits2V + 2UR. Müller
AbstractOverview on various aspects of health and disease (health models, classification of diseases, prevention and rehabilitation, therapy, epidemiology); introduction to technical aspects (diagnostics, measurement technique); fundamentals of scientific working (ethics, literature search, study design, data collection, data analysis and data presentation).
ObjectiveStudents should know the terms, models and classification systems used in health and disease; in addition, they should understand the methods of scientific working.
Content- Health: biomedical model and classification of diseases, salutogenesis and ICF, prevention and rehabilitation, therapy, epidemiology.
- Technology: diagnostics, measurement technology, automatic control engineering.
- Science: ethics, literature search, study design, tests, data analysis, data presentation
First Year Laboratory Courses
NumberTitleTypeECTSHoursLecturers
376-0003-01LDemonstration Week Health Sciences and Technology Restricted registration - show details
Only for Health Sciences and Technology BSc.
O1 credit2PR. Müller, W. Langhans, S. Lorenzetti, R. Riener, M. Ristow, M. E. Schwab, N. Wenderoth, further lecturers
AbstractDelivery of practical insight into research methods relevant to the field by means of demonstrations and small projects in the areas of Human Movement Science and Sport, Medical Technology, Molecular Health Sciences, and Neurosciences.
ObjectiveStudents can experience research methods that may arise in the field of Health Sciences and Technology.
Content- Human Movement Science and Sport: movement analysis, biomechanical measurement techniques
- Medical Technology: prostheses
- Molecular Health Sciences: metabolism, behaviour
- Neurosciences: neurological measurement techniques, neurorehabilitation
- Clinical Research
Second Year Compulsary Subjects
Examination Blocks
Examination Block 1
NumberTitleTypeECTSHoursLecturers
551-0103-00LFundamentals of Biology II: Cell BiologyO5 credits5VE. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner
AbstractThe goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ObjectiveThe goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ContentThe focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research.
Lecture notesThe lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site.
LiteratureThe lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244
(paperback).
Prerequisites / NoticeSome of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction.
376-0002-00LProduct Design in Medical Engineering Information O4 credits2V + 2US. J. Ferguson
AbstractThis course will provide insight into various aspects of medical device design such as patient needs assessment, product specification, research and technical design, validation, regulatory affairs and clinical evaluation.
ObjectiveThe goal of this lecture series is to enable the students to (i) identify the principal functional requirements for a medical device, (ii) to understand the mechanical properties of natural tissues and synthetic biomaterials, (iii) to apply this information and a basic knowledge of mechanics in the calculation of implant performance, (iv) to develop a plan for the pre-clinical evaluation and regulation of a new device.
Content1. Introduction to Medical Technology
2. Design Process
3. Mechanics
4. Mechanics of Materials
5. Tissue Mechanics
6. Prostheses: Biomechanics and Design
7. Prostheses: Biomaterials, Surfaces and Wear
8. Allografts: Heart Valves
9. Preclinical Evaluation
10. Regulatory Affairs (MepV, FDA, CE)
11. Intellectual Property
12. Group Work and Presentation
Lecture notesLink
Examination Block 2
NumberTitleTypeECTSHoursLecturers
401-0293-00LMathematics IIIO3 credits2V + 1UA. Caspar, N. Hungerbühler
AbstractVertiefung der mehrdimensionalen Analysis mit Schwerpunkt in der Anwendung der partiellen Differentialgleichungen, Vertiefung der Linearen Algebra und Einführung in die Systemanalyse und Modellbildung.X
ObjectiveDie Studierenden

+ verstehen Mathematik als Sprache zur Modellbildung und als Werkzeug zur Lösung
angewandter Probleme in den Naturwissenschaften.
+ können anspruchsolle Modelle analysieren, Lösungen qualitativ beschreiben oder
allenfalls explizit berechnen: diskret/kontinuierlich in Zeit, Ebene und Raum.
+ können Beispiele und konkrete arithmetische und geometrische Situationen
der Anwendungen mit Methoden der höheren Mathematik interpretieren und bearbeiten.
Content### Modellbildung ###

- Einführung und Beispiele
- Mehrdimensionale Modelle
- Pocken-Modell
- SIR-Modell

### Lineare Modelle ###

- Vektorräume
- Diagonalisierbarkeit
- Normalformen
- Exponential einer Matrix
- Lösungsraum eines Linearen DGL-Systems

### Fourier-Reihen ###

- Euklidische Vektorräume
- Orthogonale Projektion
- Anwendungen

### Nichtlineare Modelle ###

- Stationäre Lösungen, Qualitative Aussagen
- Mehrdimensionale Modelle: Räuber-Beute, Lotka-Volterra

### Partielle Differentialgleichungen ###

- Einführung, Repetition, Beispiele
- Fourier-Methoden: Wärmeleitung, Laplace, Wellengleichung,
Filter, Computertomographie

### Laplace-Transformation ###

- Definition und Notation
- Rechenregeln
- Anwendungsbeispiel
Lecture notesII (nächstes Semester)
Für Reglement
(Prüfungsblock) Bachelor-Studiengang Maschineningenieurwissenschaften 2010; Ausgabe 15.01.2013 (Prüfungsblock)
LiteratureSiehe Lernmaterial > LiteraturII (nächstes Semester)
Für Reglement
(Prüfungsblock) Bachelor-Studiengang Maschineningenieurwissenschaften 2010; Ausgabe 15.01.2013 (Prüfungsblock)
Prerequisites / NoticeVorlesungen Mathematik I/II
401-0643-13LStatistics IIO3 credits2V + 1UM. Kalisch
AbstractVertiefung von Statistikmethoden. Nach dem detailierten Fundament aus Statistik I liegt nun der Fokus auf konzeptueller Breite und konkreter Problemlösungsfähigkeit mit der Statistiksoftware R.
ObjectiveNach diesem Kurs können Sie mit der Statistiksoftware R Daten einlesen, auf vielfältige Art verarbeiten und Grafiken für Berichte oder Vorträge exportieren. Sie verstehen die Konzepte von Methoden wie Lineare Regression (mit Faktoren, Interaktion, Modellwahl), ANOVA (1-weg, 2-weg), Chi-Quadrat-Test, Fisher-Test, GLMs, Mixed Models, Clustering, PCA und können diese mit der Statistiksoftware R in der Praxis umsetzen. Zudem kennen Sie die Grundprinzipien von gutem experimentellem Design und können bestehende Studien kritisch hinterfragen.
Examination Block 3
NumberTitleTypeECTSHoursLecturers
376-0151-00LAnatomy and Physiology I Information O5 credits4VM. Ristow, K. De Bock, L. Slomianka, C. Spengler, N. Wenderoth, D. P. Wolfer
AbstractBasic knowledge of the anatomy and physiology of tissues, of the embryonal and postnatal development, of the basic terminology of pathology, the neuro-muscular system, the cardiovascular system and the respiratory system.
ObjectiveBasic knowledge of human anatomy and physiology and basics of clinical pathophysiology.
ContentShort overview of human anatomy, physiology and general pathology.

Anatomy and Physiology I (fall term):
Basics of cytology, histology, embryology, general pathology; nervous system, muscles, cardiovascular system, respiratory system

Anatomy and Physiology II (spring term):
digestive system, kidney and urinary tract, endocrine system, skin, thermoregulation, sensory organs, male and female reproductive system, pregnancy and child birth.
Lecture notes"Wolfer, Rhyner, Sebele und Müntener: "Anatomie und Physiologie"; Link"
LiteratureAnatomie:

Schiebler TH, Korf H-W: Anatomie (10. vollständig überarbeitete Auflage)
Steinkopff / Springer, Heidelberg 2007

Martini FH, Timmons MJ, Tallitsch RB. Human Anatomy
6th edition, Pearson, San Francisco 2008, (7. Auflage Juli 2011)

Physiologie:
Schmidt/Lang/Heckmann: Physiologie des Menschen, Springer-Verlag, Heidelberg (31. Auflage)
Prerequisites / NoticeVoraussetzungen: 1. Jahr, naturwissenschaftlicher Teil
402-0043-00LPhysics IO4 credits3V + 1UT. Esslinger
AbstractIntroduction to the concepts and tools in physics with the help of demonstration experiments: mechanics of point-like and ridged bodies, periodic motion and mechanical waves.
ObjectiveThe concepts and tools in physics, as well as the methods of an experimental science are taught. The student should learn to identify, communicate and solve physical problems in his/her own field of science.
ContentMechanics (motion, Newton's laws, work and energy, conservation of momentum, rotation, gravitation, fluids)
Periodic Motion and Waves (periodic motion, mechanical waves, acoustics).
Lecture notesThe lecture follows the book "Physics" by Paul A. Tipler.
LiteraturePaul A. Tipler and Gene P. Mosca, Physics (for Scientists and Engineers), W. H. Freeman and Company
Prerequisites / NoticePrerequisites: Mathematics I & II
Examination Block 4
NumberTitleTypeECTSHoursLecturers
376-0007-00LAdvanced Anatomy and Physiology I Restricted registration - show details
Only for Health Sciences and Technology BSc.
O2 credits2VK. De Bock, N. Wenderoth, D. P. Wolfer
AbstractAdvanced knowledge of anatomy and physiology, molecular mechanisms and cellular function of tissues as well as pathophysiological aspects of different organ systems.
ObjectiveAdvanced knowledge of human anatomy and physiology and of molecular and pathophysiological aspects.
ContentAdvanced Anatomy and Physiology I (fall term):
Closer look to the nervous system,
Advanced Anatomy and Physiology II (spring term):
Introduction to Molecular Biology; Closer look to muscles, cardiovascular system, and respiratory system as well as immunology.
Third Year Focus Courses
Focus Courses: Human Movement Science and Sport
NumberTitleTypeECTSHoursLecturers
376-0203-00LMovement and Sport Biomechanics Information W4 credits3GW. R. Taylor, R. List, S. Lorenzetti
AbstractLearning to view the human body as a (bio-) mechanical system. Making the connections between everyday movements and sports activity with injury, discomfort, prevention and rehabilitation.
ObjectiveStudents are able to describe the human body as a mechanical system.
They analyse and describe human movement according to the laws of mechanics.
ContentMovement- and sports biomechanics deals with the attributes of the human body and their link to mechanics. The course includes topics such as functional anatomy, biomechanics of daily activities (gait, running, etc.) and looks at movement in sport from a mechanical point of view. Furthermore, simple reflections on the loading analysis of joints in various situations are discussed. Additionally, questions covering the statics and dynamics of rigid bodies, and inverse dynamics, relevant to biomechanics are investigated.
376-0207-00LExercise PhysiologyW4 credits3GC. Spengler
AbstractThis course provides an overview over molecular and systemic aspects of neuromuscular, cardiovascular and respiratory adaptations to acute and chronic exercise as well as the interactions of the different systems influencing factors, e.g. genetics, gender, age, altitude/depth, heat/cold, with respect to performance and health.
ObjectiveThe aim of this course is to understand molecular and systemic aspects of neuromuscular, cardiovascular and respiratory adaptations to acute and chronic exercise as well as the interaction of the different systems regarding health-relevant aspects and performance in healthy people and persons with selected diseases. Furthermore, students will understand the influence of genetics, gender, age, altitude/depth, heat and cold on the named factors.
ContentHistory of Exercise Physiology, research methods, fibertype heterogeneity and its functional significance, neural control of muscle force, molecular nad cellular mechanisms of muscle adaptation to resistance, endurance and stretching exercise, interindividual variability in the response to training, cardiorespiratory and metabolic responses to acute and chronic exercise, sexi differences relevant to exercise performance, exercise in hot and cold environment, children and adolescents in sport and exercise, exercise at altitude and depth, aging and exercise performance, exercise for health, exercise in the context of disease.
Lecture notesOnline material is provided during the course.
LiteratureRecommended textbooks:

William D. McArdle, Frank I. Katch, Victor L. Katch
Exercise Physiology: Nutrition, Energy, and Human Performance, Eighth Edition, 2014
ISBN/ISSN: 9781451191554

W.L. Kenney, J.H. Wilmore, D.L. Costill
Physiology of Sport and Exercise
5th Edition, 2012
ISBN-13: 978-0-7360-9409-2 / ISBN-10: 0-7360-9409-1
Prerequisites / NoticeAnatomy and Physiology I + II
Focus Courses: Molecular Health Sciences
NumberTitleTypeECTSHoursLecturers
551-0309-00LConcepts in Modern GeneticsW6 credits4VY. Barral, D. Bopp, A. Hajnal, M. Stoffel, O. Voinnet
AbstractConcepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
ObjectiveThis course focuses on the concepts of classical and modern genetics and genomics.
ContentThe topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
Lecture notesScripts and additional material will be provided during the semester.
Prerequisites / NoticeThis course is a co-production of the University of Zurich and ETH Zurich, and will be taught in English. The course takes place on Monday afternoon at ETH Hoenggerberg, and on Tuesday morning at UZH Irchel.
Focus Courses: Medical Technology
NumberTitleTypeECTSHoursLecturers
376-0021-00LIntroduction to Biomedical Engineering IW4 credits3GP. Christen, R. Müller, J. G. Snedeker, M. Zenobi-Wong
AbstractIntroduction to biomechanics, biomaterials, tissue engineering, medical imaging as well as the history of biomedical engineering.
ObjectiveUnderstanding of physical and technical principles in biomechanics, biomaterials, tissue engineering, medical imaging as well as the history of biomedical engineering. Mathematical description and problem solving. Knowledge of biomedical engineering applications in research and clinical practice.
ContentTissue and Cellular Biomechanics, Molecular Biomechanics and Biopolymers, Computational Biomechanics, Biomaterials, Tissue Engineering, Radiation and Radiographic Imaging, Diagnostic Ultrasound Imaging, Magnetic Resonance Imaging,
Biomedical Optics and Lasers.
Lecture notesStored on ILIAS.
LiteratureIntroduction to Biomedical Engineering, 3rd Edition 2011,
Autor: John Enderle, Joseph Bronzino, ISBN 9780123749796
Academic Press
376-1714-00LBiocompatible MaterialsW4 credits3GK. Maniura, J. Möller, M. Zenobi-Wong
AbstractIntroduction to molecules used for biomaterials, molecular interactions between different materials and biological systems (molecules, cells, tissues). The concept of biocompatibility is discussed and important techniques from biomaterials research and development are introduced.
ObjectiveThe class consists of three parts:
1. Introdcution into molecular characteristics of molecules involved in the materials-to-biology interface. Molecular design of biomaterials.
2. The concept of biocompatibility.
3. Introduction into methodology used in biomaterials research and application.
ContentIntroduction into native and polymeric biomaterials used for medical applications. The concepts of biocompatibility, biodegradation and the consequences of degradation products are discussed on the molecular level. Different classes of materials with respect to potential applications in tissue engineering and drug delivery are introduced. Strong focus lies on the molecular interactions between materials having very different bulk and/or surface chemistry with living cells, tissues and organs. In particular the interface between the materials surfaces and the eukaryotic cell surface and possible reactions of the cells with an implant material are elucidated. Techniques to design, produce and characterize materials in vitro as well as in vivo analysis of implanted and explanted materials are discussed.
In addition, a link between academic research and industrial entrepreneurship is established by external guest speakers.
Lecture notesHandouts can be accessed online.
LiteratureLiteratur
Biomaterials Science: An Introduction to Materials in Medicine, Ratner B.D. et al, 3rd Edition, 2013
Comprehensive Biomaterials, Ducheyne P. et al., 1st Edition, 2011

(available online via ETH library)

Handouts provided during the classes and references therin.
Focus Courses: Neurosciences
NumberTitleTypeECTSHoursLecturers
376-1305-00LDevelopment of the Nervous SystemW3 credits2VE. Stoeckli, further lecturers
AbstractThe course covers the development of the nervous system (NS) with a focus on neurogenesis and migration, axon growth, synapse formation, mol. & cell. mechanisms, and diseases of the developing NS.
ObjectiveThe aim is to give a deepened insight on the normal development, of the nervous system based on molecular, cellular and biochemical approaches.
ContentThe main focus is on the development of the NS: Early development of the NS, cellular processes, nerve fiber growth, building of synapses and neuronal networks.
Lecture notesMust be downloaded from OLAT: Link
as BIO344
LiteratureThe lecture requires reading of book chapters, handouts and original scientific papers. Further information will be given in the individual lectures and are mentioned on OLAT.
Prerequisites / NoticeAuxiliary tools:
None. Bring something to write and your student ID
  •  Page  1  of  4 Next page Last page     All