Suchergebnis: Katalogdaten im Herbstsemester 2018

Chemie Master Information
Master-Studium (Studienreglement 2018)
Wahlfächer
Organische Chemie
NummerTitelTypECTSUmfangDozierende
529-0243-01LTransition Metal Catalysis: From Mechanisms to Applications Information W6 KP3GB. Morandi
KurzbeschreibungDetailed discussion of selected modern transition metal catalyzed reactions from a synthetic and mechanistic viewpoint
LernzielUnderstanding and critical evaluation of current research in transition metal catalysis. Design of mechanistic experiments to elucidate reaction mechanisms. Synthetic relevance of transition metal catalysis. Students will also learn about writing an original research proposal during a workshop.
InhaltDetailed discussion of selected modern transition metal catalyzed reactions from a synthetic and mechanistic viewpoint. Synthetic applications of these reactions. Introduction and application of tools for the elucidation of mechanisms. Selected examples of topics include: C-H activation, C-O activation, C-C activation, gold catalysis, redox active ligands, main group redox catalysis, frustrated Lewis pairs.
SkriptLecture slides will be provided online. A Handout summarizing important concepts in organometallic and physical organic chemistry will also be provided. Useful references and handouts will also be provided during the workshop.

Slides will be uploaded 1-2 days before each lecture on Link (password will be given during the first lecture or can be requested by email)
LiteraturPrimary literature and review articles will be cited during the course.

The following textbooks can provide useful support for the course:

- Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books.
- Crabtree R., The Organometallic Chemistry of the Transition Metals, John Wiley & Sons, Inc.
- Hartwig J., Organotransition Metal Chemistry: From Bonding to Catalysis, University Science Books.
- J. P. Collman, L. S. Hegedus, J. R. Norton, R. G. Finke, Principles and Applications of Organotransition Metal Chemistry.
Voraussetzungen / BesonderesRequired level: Courses in organic and physical chemistry of the first and second year as well as ACIII

Special requirement: each participant will have to come up with an independent research proposal to be presented orally at the end of the semester. A dedicated workshop will be organized in the middle of the semester to introduce the students to proposal writing and presentation.
529-0233-01LOrganic Synthesis: Methods and Strategies Information W6 KP3GE. M. Carreira
KurzbeschreibungThe complex relation between structural analysis, methods leading to desired transformations, and insight into reaction mechanisms is exemplified. Relations between retrosynthetic analysis of target structures, synthetic methods and their combination in a synthetic strategy.
LernzielExtension and deepening of the knowledge in organic synthesis.
InhaltBegriffe der Planung (Strategie und Taktik) der organischen Synthese, Retrosynthetische Analyse, Vertiefung der Beziehungen zwischen Struktur und Reaktivität im Zusammenhang mit der Synthese organischer Verbindungen zunehmender Komplexität. Vertiefung und Ergänzung der Kenntnisse synthetischer Methoden.
LiteraturK. C. Nicolaou, E. J. Sorensen, Classics in Total Synthesis, Wiley-VCH 1996.
K. C. Nicolaou, S. A. Snyder, Classics in Total Synthesis II, Wiley-VCH 2003.
K. C. Nicolaou, J. Chen, Classics in Total Synthesis III, Wiley-VCH 2011.
Voraussetzungen / BesonderesOC I-IV
529-0241-10LAdvanced Methods and Strategies in SynthesisW6 KP3GJ. W. Bode
KurzbeschreibungAdvanced Modern Methods and Strategies in Synthesis
LernzielKenntnis der modernen Methoden der asymmetrischen Synthese, der enantioselektiven Katalyse, und organische Reactionsmechanismus.
InhaltAktuelle Trends in Methoden für und Annäherungen an die Synthese von komplexen Naturstoffen, Pharmazeutika und biologischen Molekülen, Fragmentkopplungs- und Schutzgruppenstrategien; chemische Ligation und Biomolekülsynthese; enantioselektive Katalyse einschließlich Ligandendesign und -optimierung; Kreuzkupplungsreaktionen voraktivierter Vorstufen; C-H-Aktivierung und Oxidationen; Bausteinsynthese mit chiralen Auxilliaren und Reagenzien; neue Konzepte in der asymmetrischen Katalyse. Analyse von Schlüsselliteratur inklusive der Erkennung von Trends, bedeutenden Präzedenzfällen und neu aufkommenden Gebieten wird hervorgehoben.
Skriptwill be provided in class and online
LiteraturSuggesting Textbooks
1. Walsh and Kozlowski, Fundamentals of Asymmetric Catalysis, 1st Ed., University Science Books, 2009.
2. Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books, 2006.
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