Suchergebnis: Katalogdaten im Frühjahrssemester 2018

Nummer	Titel	Typ	ECTS	Umfang	Dozierende
MAS in Medizinphysik
Obligatorische Fächer (für beide Fachrichtungen)
465-0954-00L	Anatomy and Physiology for Medical Physicists II Findet dieses Semester nicht statt.	O	2 KP	2V
Kurzbeschreibung	Anatomie und Physiologie für Medizinphysiker I & II vermittelt Grundkenntnisse in Biochemie und Zellphysiologie sowie im Hauptteil eine vertiefte Einführung in die Funktionen und Eigenschaften der Gewebe, der Organe, von Organsystemen und des menschlichen Körpers als System.
Lernziel	Der Kurs vermittelt physiologische und anatomische Grundlagen und die professionelle medizinische Terminologie, die Medizinphysiker und Medizinphysikerinnen befähigt, in interdisziplinären Arbeitsgruppen vollwertig teilzunehmen, Zugang zur medizinischen Fachliteratur zu gewinnen und mit Profit an interdisziplinären oder medizinischen Konferenzen teilzunehmen.
465-0952-00L	Biomedical Photonics Findet dieses Semester nicht statt.	O	3 KP	2V
Kurzbeschreibung	The lecture introduces the principles of generation, propagation and detection of light and its therapeutic and diagnostic application in medicine.
Lernziel	The lecture provides knowledge about light sources and light delivery systems, optical biomedical imaging techniques, optical measurement technologies and their specific applications in medicine. Fundamental principles will be accompanied by practical and contemporary examples. Different selected optical systems used in diagnostics and therapy will be discussed.
Inhalt	Optics always was strongly connected to the observation and interpretation of physiological phenomenon. The basic knowledge of optics for example was initially gained by studying the function of the human eye. Nowadays, biomedical optics is an independent research field that is no longer restricted to the observation of physiological processes but studies diagnostic and therapeutic problems in medicine. A basic prerequisite for applying optical techniques in medicine is the understanding of the physical properties of light, the light propagation in and its interaction with tissue. The lecture gives inside into the generation, propagation and detection of light, its propagation in tissue and into selected optical applications in medicine. Various optical imaging techniques (optical coherence tomography or optoacoustics) as well as therapeutic laser applications (refractive surgery, photodynamic therapy or nanosurgery) will be discussed.
Skript	will be provided via Internet (Ilias)
Literatur	- M. Born, E. Wolf, "Principles of Optics", Pergamon Press - B.E.A. Saleh, M.C. Teich, "Fundamentals of Photonics", John Wiley and Sons, Inc. - O. Svelto, "Principles of Lasers", Plenum Press - J. Eichler, T. Seiler, "Lasertechnik in der Medizin", Springer Verlag - M.H. Niemz, "Laser-Tissue Interaction", Springer Verlag - A.J. Welch, M.J.C. van Gemert, "Optical-thermal response of laser-irradiated tissue", Plenum Press
Voraussetzungen / Besonderes	Language of instruction: English This is the same course unit (465-0952-00L) with former course title "Medical Optics".
465-0958-00L	Audiological Acoustics Findet dieses Semester nicht statt.	O	1 KP	1V	F. Pfiffner
Kurzbeschreibung	After introducing acoustic objects of the physical world the detection, analysis and perception of these signals in the peripheral and central auditory system is described. Emphasis is put on understanding the processing mechanisms in the human auditory system in the aim of restoring impaired auditory function with medical technology.
Lernziel	The understanding of the human hearing organ, the processing of complex acoustic signals and hearing rehabilitation possibilities with medical devices (hearing aid and implantable hearing aid systems).
Inhalt	Physiology and anatomy of the human organ of hearing, fundamentals of acoustics, audiological (Hearing) diagnostic procedures with acoustics, psychoacoustics and electrophysiology methods hearing losses and hearing rehabilitation
Literatur	ATCHERSON, Samuel R.; STOODY, Tina M. (Hg.). Auditory electrophysiology: a clinical guide. Thieme, 2012. ROESER, Ross J., et al. Audiology-Diagnosis. New York: Thieme, 2007, 2007. KOMPIS, Martin. Audiologie. Huber, 2009. KATZ, Jack; Handbook of clinical audiology, 2002.
227-0396-00L	EXCITE Interdisciplinary Summer School on Bio-Medical Imaging The school admits 60 MSc or PhD students with backgrounds in biology, chemistry, mathematics, physics, computer science or engineering based on a selection process. Students have to apply for acceptance by April 23, 2018. To apply a curriculum vitae and an application letter need to be submitted. The notification of acceptance will be given by May 25, 2018. Further information can be found at: www.excite.ethz.ch.	O	4 KP	6G	S. Kozerke, G. Csúcs, J. Klohs-Füchtemeier, S. F. Noerrelykke, M. P. Wolf
Kurzbeschreibung	Two-week summer school organized by EXCITE (Center for EXperimental & Clinical Imaging TEchnologies Zurich) on biological and medical imaging. The course covers X-ray imaging, magnetic resonance imaging, nuclear imaging, ultrasound imaging, infrared and optical microscopy, electron microscopy, image processing and analysis.
Lernziel	Students understand basic concepts and implementations of biological and medical imaging. Based on relative advantages and limitations of each method they can identify preferred procedures and applications. Common foundations and conceptual differences of the methods can be explained.
Inhalt	Two-week summer school on biological and medical imaging. The course covers concepts and implementations of X-ray imaging, magnetic resonance imaging, nuclear imaging, ultrasound imaging, infrared and optical microscopy and electron microscopy. Multi-modal and multi-scale imaging and supporting technologies such as image analysis and modeling are discussed. Dedicated modules for physical and life scientists taking into account the various backgrounds are offered.
Skript	Hand-outs, Web links
Voraussetzungen / Besonderes	The school admits 60 MSc or PhD students with backgrounds in biology, chemistry, mathematics, physics, computer science or engineering based on a selection process. To apply a curriculum vitae, a statement of purpose and applicants references need to be submitted. Further information can be found at: http://www.excite.ethz.ch/education/summer-school.html

Fachrichtung: Strahlentherapie
Kernfächer
Nummer	Titel	Typ	ECTS	Umfang	Dozierende
227-0968-00L	Monte Carlo in Medical Physics	O	4 KP	3G	M. Stampanoni, M. K. Fix
Kurzbeschreibung	Introduction in basics of Monte Carlo simulations in the field of medical radiation physics. General recipe for Monte Carlo simulations in medical physics from code selection to fine-tuning the implementation. Characterization of radiation by means of Monte Carlo simulations.
Lernziel	Understanding the concept of the Monte Carlo method. Getting familiar with the Monte Carlo technique, knowing different codes and several applications of this method. Learn how to use Monte Carlo in the field of applied medical radiation physics. Understand the usage of Monte Carlo to characterize the physical behaviour of ionizing radiation in medical physics. Share the enthusiasm about the potential of the Monte Carlo technique and its usefulness in an interdisciplinary environment.
Inhalt	The lecture provides the basic principles of the Monte Carlo method in medical radiation physics. Some fundamental concepts on applications of ionizing radiation in clinical medical physics will be reviewed. Several techniques in order to increase the simulation efficiency of Monte Carlo will be discussed. A general recipe for performing Monte Carlo simulations will be compiled. This recipe will be demonstrated for typical clinical devices generating ionizing radiation, which will help to understand implementation of a Monte Carlo model. Next, more patient related effects including the estimation of the dose distribution in the patient, patient movements and imaging of the patient's anatomy. A further part of the lecture covers the simulation of radioactive sources as well as heavy ion treatment modalities. The field of verification and quality assurance procedures from the perspective of Monte Carlo simulations will be discussed. To complete the course potential future applications of Monte Carlo methods in the evolving field of treating patients with ionizing radiation.
Skript	A script will be provided.
402-0342-00L	Medical Physics II	O	6 KP	2V + 1U	P. Manser
Kurzbeschreibung	Applications of ionizing radiation in medicine such as radiation therapy, nuclear medicine and radiation diagnostics. Theory of dosimetry based on cavity theory and clinical consequences. Fundamentals of dose calculation, optimization and evaluation. Concepts of external beam radiation therapy and brachytherapy. Recent and future developments: IMRT, IGRT, SRS/SBRT, particle therapy.
Lernziel	Getting familiar with the different medical applications of ionizing radiation in the fields of radiation therapy, nuclear medicine, and radiation diagnostics. Dealing with concepts such as external beam radiation therapy as well as brachytherapy for the treatment of cancer patients. Understanding the fundamental cavity theory for dose measurements and its consequences on clinical practice. Understanding different delivery techniques such as IMRT, IGRT, SRS/SBRT, brachytherapy, particle therapy using protons, heavy ions or neutrons. Understanding the principles of dose calculation, optimization and evaluation for radiation therapy, nuclear medicine and radiation diagnostic applications. Finally, the lecture aims to demonstrate that medical physics is a fascinating and evolving discipline where physics can directly be used for the benefits of patients and the society.
Inhalt	In this lecture, the use of ionizing radiation in different clinical applications is discussed. Primarily, we will concentrate on radiation therapy and will cover applications such as external beam radiotherapy with photons and electrons, intensity modulated radiotherapy (IMRT), image guided radiotherapy (IGRT), stereotactic radiotherapy and radiosurgery, brachytherapy, particle therapy using protons, heavy ions or neutrons. In addition, dosimetric methods based on cavity theory are reviewed and principles of treatment planning (dose calculation, optimization and evaluation) are discussed. Next to these topics, applications in nuclear medicine and radiation diagnostics are explained with the clear focus on dosimetric concepts and behaviour.
Skript	A script will be provided.
Voraussetzungen / Besonderes	It is recommended that the students have taken the lecture Medical Physics I in advance.
465-0968-00L	Medizinphysik in der Praxis	O	2 KP	2V	P. Manser, Referent/innen
Kurzbeschreibung	Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen. Ein wichtiger Bestandteil ist dabei, den Dialog zwischen den Studierenden und den Praktikern zu fördern und Kontakte zu schaffen. Hierzu berichten verschiedene Dozenten aus der ganzen Schweiz über ihre Arbeit als Medizinphysiker.
Lernziel	Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen.

Praktika
Nummer	Titel	Typ	ECTS	Umfang	Dozierende
465-0420-00L	Strahlenschutz-Sachverstand Nur für MAS in Medizinphysik	O	4 KP	6G	externe Veranstalter
Kurzbeschreibung	Der Kurs umfasst alle Inhalte in Theorie und Praxis, die für eine anerkannte Ausbildung zu Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktivem Material in einem Arbeitsbereich B/C notwendig sind. Nach erfolgreich abgeschlossener Prüfung wird ein vom BAG anerkanntes Zertifikat ausgestellt. Dieses erlaubt auch den Einsatz als Strahlenschutz-Beauftragte im Aufsichtsbereich des ENSI.
Lernziel	Die Teilnehmenden erwerben in der Ausbildung die Kompetenzen, Fähigkeiten und Kenntnisse, um die Funktion des Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktiven Material im Arbeitsbereich B/C anerkannt gemäss Strahlenschutz Ausbildungsverordnung (814.501.261) ausüben zu dürfen.
Inhalt	- Grundkenntnisse der Strahlenphysik und der Strahlenbiologie - Dosisabschätzung bei interner und externer Bestrahlung - Kenntnis der für den Umgang mit offenen und geschlossenen Strahlenquellen massgeblichen Gesetzen und Verordnungen - Erkennen und abschätzen von Gefährdungspotenzialen - Festlegen von Strahlenschutz-Betriebsvorschriften, Sicherheitsplänen sowie baulicher, organisatorischer und operationeller Massnahmen - Kenntnis und Anwendung von Messgeräten - Planung und Durchführung der Personen- und Arbeitsplatzüberwachung

Fachrichtung: Allg. Medizinphysik und Biomedizinisches Ingenieurwesen
Vertiefung Radiation Therapy
Kernfächer
Nummer	Titel	Typ	ECTS	Umfang	Dozierende
227-0968-00L	Monte Carlo in Medical Physics	W	4 KP	3G	M. Stampanoni, M. K. Fix
Kurzbeschreibung	Introduction in basics of Monte Carlo simulations in the field of medical radiation physics. General recipe for Monte Carlo simulations in medical physics from code selection to fine-tuning the implementation. Characterization of radiation by means of Monte Carlo simulations.
Lernziel	Understanding the concept of the Monte Carlo method. Getting familiar with the Monte Carlo technique, knowing different codes and several applications of this method. Learn how to use Monte Carlo in the field of applied medical radiation physics. Understand the usage of Monte Carlo to characterize the physical behaviour of ionizing radiation in medical physics. Share the enthusiasm about the potential of the Monte Carlo technique and its usefulness in an interdisciplinary environment.
Inhalt	The lecture provides the basic principles of the Monte Carlo method in medical radiation physics. Some fundamental concepts on applications of ionizing radiation in clinical medical physics will be reviewed. Several techniques in order to increase the simulation efficiency of Monte Carlo will be discussed. A general recipe for performing Monte Carlo simulations will be compiled. This recipe will be demonstrated for typical clinical devices generating ionizing radiation, which will help to understand implementation of a Monte Carlo model. Next, more patient related effects including the estimation of the dose distribution in the patient, patient movements and imaging of the patient's anatomy. A further part of the lecture covers the simulation of radioactive sources as well as heavy ion treatment modalities. The field of verification and quality assurance procedures from the perspective of Monte Carlo simulations will be discussed. To complete the course potential future applications of Monte Carlo methods in the evolving field of treating patients with ionizing radiation.
Skript	A script will be provided.
402-0342-00L	Medical Physics II	W	6 KP	2V + 1U	P. Manser
Kurzbeschreibung	Applications of ionizing radiation in medicine such as radiation therapy, nuclear medicine and radiation diagnostics. Theory of dosimetry based on cavity theory and clinical consequences. Fundamentals of dose calculation, optimization and evaluation. Concepts of external beam radiation therapy and brachytherapy. Recent and future developments: IMRT, IGRT, SRS/SBRT, particle therapy.
Lernziel	Getting familiar with the different medical applications of ionizing radiation in the fields of radiation therapy, nuclear medicine, and radiation diagnostics. Dealing with concepts such as external beam radiation therapy as well as brachytherapy for the treatment of cancer patients. Understanding the fundamental cavity theory for dose measurements and its consequences on clinical practice. Understanding different delivery techniques such as IMRT, IGRT, SRS/SBRT, brachytherapy, particle therapy using protons, heavy ions or neutrons. Understanding the principles of dose calculation, optimization and evaluation for radiation therapy, nuclear medicine and radiation diagnostic applications. Finally, the lecture aims to demonstrate that medical physics is a fascinating and evolving discipline where physics can directly be used for the benefits of patients and the society.
Inhalt	In this lecture, the use of ionizing radiation in different clinical applications is discussed. Primarily, we will concentrate on radiation therapy and will cover applications such as external beam radiotherapy with photons and electrons, intensity modulated radiotherapy (IMRT), image guided radiotherapy (IGRT), stereotactic radiotherapy and radiosurgery, brachytherapy, particle therapy using protons, heavy ions or neutrons. In addition, dosimetric methods based on cavity theory are reviewed and principles of treatment planning (dose calculation, optimization and evaluation) are discussed. Next to these topics, applications in nuclear medicine and radiation diagnostics are explained with the clear focus on dosimetric concepts and behaviour.
Skript	A script will be provided.
Voraussetzungen / Besonderes	It is recommended that the students have taken the lecture Medical Physics I in advance.

Praktika
Nummer	Titel	Typ	ECTS	Umfang	Dozierende
465-0420-00L	Strahlenschutz-Sachverstand Nur für MAS in Medizinphysik	W	4 KP	6G	externe Veranstalter
Kurzbeschreibung	Der Kurs umfasst alle Inhalte in Theorie und Praxis, die für eine anerkannte Ausbildung zu Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktivem Material in einem Arbeitsbereich B/C notwendig sind. Nach erfolgreich abgeschlossener Prüfung wird ein vom BAG anerkanntes Zertifikat ausgestellt. Dieses erlaubt auch den Einsatz als Strahlenschutz-Beauftragte im Aufsichtsbereich des ENSI.
Lernziel	Die Teilnehmenden erwerben in der Ausbildung die Kompetenzen, Fähigkeiten und Kenntnisse, um die Funktion des Strahlenschutz-Sachverständigen beim Umgang mit offenem radioaktiven Material im Arbeitsbereich B/C anerkannt gemäss Strahlenschutz Ausbildungsverordnung (814.501.261) ausüben zu dürfen.
Inhalt	- Grundkenntnisse der Strahlenphysik und der Strahlenbiologie - Dosisabschätzung bei interner und externer Bestrahlung - Kenntnis der für den Umgang mit offenen und geschlossenen Strahlenquellen massgeblichen Gesetzen und Verordnungen - Erkennen und abschätzen von Gefährdungspotenzialen - Festlegen von Strahlenschutz-Betriebsvorschriften, Sicherheitsplänen sowie baulicher, organisatorischer und operationeller Massnahmen - Kenntnis und Anwendung von Messgeräten - Planung und Durchführung der Personen- und Arbeitsplatzüberwachung
465-0800-00L	Practical Work Nur für MAS in Medizinphysik	W	4 KP		externe Veranstalter
Kurzbeschreibung	The practical work is designed to train the students in the solution of a specific problem and provides insights in the field of the selected MAS specialization. Tutors propose the subject of the project, the project plan, and the roadmap together with the student, as well as monitor the overall execution.
Lernziel	The practical work is aimed at training the student’s capability to apply and connect specific skills acquired during the MAS specialization program towards the solution of a focused problem.

Wahlfächer
Nummer	Titel	Typ	ECTS	Umfang	Dozierende
227-0390-00L	Elements of Microscopy	W	4 KP	3G	M. Stampanoni, G. Csúcs, A. Sologubenko
Kurzbeschreibung	The lecture reviews the basics of microscopy by discussing wave propagation, diffraction phenomena and aberrations. It gives the basics of light microscopy, introducing fluorescence, wide-field, confocal and multiphoton imaging. It further covers 3D electron microscopy and 3D X-ray tomographic micro and nanoimaging.
Lernziel	Solid introduction to the basics of microscopy, either with visible light, electrons or X-rays.
Inhalt	It would be impossible to imagine any scientific activities without the help of microscopy. Nowadays, scientists can count on very powerful instruments that allow investigating sample down to the atomic level. The lecture includes a general introduction to the principles of microscopy, from wave physics to image formation. It provides the physical and engineering basics to understand visible light, electron and X-ray microscopy. During selected exercises in the lab, several sophisticated instrument will be explained and their capabilities demonstrated.
Literatur	Available Online.
227-0946-00L	Molecular Imaging - Basic Principles and Biomedical Applications	W	2 KP	2V	M. Rudin
Kurzbeschreibung	Concept: What is molecular imaging. Discussion/comparison of the various imaging modalities used in molecular imaging. Design of target specific probes: specificity, delivery, amplification strategies. Biomedical Applications.
Lernziel	Molecular Imaging is a rapidly emerging discipline that translates concepts developed in molecular biology and cellular imaging to in vivo imaging in animals and ultimatly in humans. Molecular imaging techniques allow the study of molecular events in the full biological context of an intact organism and will therefore become an indispensable tool for biomedical research.
Inhalt	Concept: What is molecular imaging. Discussion/comparison of the various imaging modalities used in molecular imaging. Design of target specific probes: specificity, delivery, amplification strategies. Biomedical Applications.
227-0948-00L	Magnetic Resonance Imaging in Medicine	W	4 KP	3G	S. Kozerke, M. Weiger Senften
Kurzbeschreibung	Introduction to magnetic resonance imaging and spectroscopy, encoding and contrast mechanisms and their application in medicine.
Lernziel	Understand the basic principles of signal generation, image encoding and decoding, contrast manipulation and the application thereof to assess anatomical and functional information in-vivo.
Inhalt	Introduction to magnetic resonance imaging including basic phenomena of nuclear magnetic resonance; 2- and 3-dimensional imaging procedures; fast and parallel imaging techniques; image reconstruction; pulse sequences and image contrast manipulation; equipment; advanced techniques for identifying activated brain areas; perfusion and flow; diffusion tensor imaging and fiber tracking; contrast agents; localized magnetic resonance spectroscopy and spectroscopic imaging; diagnostic applications and applications in research.
Skript	D. Meier, P. Boesiger, S. Kozerke Magnetic Resonance Imaging and Spectroscopy
376-1984-00L	Lasers in Medicine	W	3 KP	3G	M. Frenz
Kurzbeschreibung	Fragen wie "Was ist ein Laser, wie funktioniert er und was macht ihn so interessant für die Medizin?", aber auch "Wie breitet sich Licht im Gewebe aus und welche Wechselwirkungen treten dabei auf?" sollen beantwortet werden. Speziell wird auf therapeutische, diagnostische und bildgebende Anwendungen anhand von ausgewählten Beispielen eingegangen.
Lernziel	Einführung in die für medizinische Anwendungen relevanten Lasertechniken. Vermittlung der physikalischen Grundlagen der Laser-Gewebe-Wechselwirkung mit dem Ziel, den Einfluss der unterschiedlichen Bestrahlungsparameter auf den Gewebeeffekt zu verstehen. Grundlagen der diagnostischen Laseranwendungen und der Lasersicherheit.
Inhalt	Die Anwendung des Lasers in der Medizin gewinnt zunehmend dort an Bedeutung, wo seine speziellen Eigenschaften gezielt zur berührungslosen, selektiven und spezifischen Wirkung auf Weich- und Hartgewebe für minimal invasive Therapieformen oder zur Eröffnung neuer therapeutischer und diagnostischer Methoden eingesetzt werden können. Grundlegende Arbeiten zum Verständnis der Lichtausbreitung im Gewebe (Absorptions-, Reflexions- und Transmissionsvermögen) und die unterschiedlichen Formen der Wechselwirkung (photochemische, thermische, ablative und optomechanische Wirkung) werden eingehend behandelt. Speziell wird auf den Einfluss der Wellenlänge und der Bestrahlungszeit auf den Wechselwirkungsmechanismus eingegangen. Die unterschiedlichen medizinisch genutzten Lasertypen und Strahlführungssysteme werden hinsichtlich ihres Einsatzes im Bereich der Medizin anhand ausgesuchter Anwendungsbeispiele diskutiert. Neben den therapeutischen Wirkungen wird auf den Einsatz des Lasers in der medizinischen Diagnostik (z.B. Tumor-Fluoreszenzdiagnostik, Bildgebung) eingegangen. Die beim Einsatz des Lasers in der Medizin erforderlichen Schutzmassnahmen werden diskutiert.
Skript	wird im Internet bereitgestellt
Literatur	- M. Born, E. Wolf, "Principles of Optics", Pergamon Press - B.E.A. Saleh, M.C. Teich, "Fundamentals of Photonics", John Wiley and Sons, Inc. - A.E. Siegman, "Lasers", University Science Books - O. Svelto, "Principles of Lasers", Plenum Press - J. Eichler, T. Seiler, "Lasertechnik in der Medizin", Springer Verlag - M.H. Niemz, "Laser-Tissue Interaction", Springer Verlag - A.J. Welch, M.J.C. van Gemert, "Optical-thermal response of laser-irradiated tissue", Plenum Press
402-0343-00L	Physics Against Cancer: The Physics of Imaging and Treating Cancer	W	6 KP	2V + 1U	A. J. Lomax, U. Schneider
Kurzbeschreibung	Radiotherapy is a rapidly developing and technology driven medical discipline that is heavily dependent on physics and engineering. In this lecture series, we will review and describe some of the current developments in radiotherapy, particularly from the physics and technological view point, and will indicate in which direction future research in radiotherapy will lie.
Lernziel	Radiotherapy is a rapidly developing and technology driven medical discipline that is heavily dependent on physics and engineering. In the last few years, a multitude of new techniques, equipment and technology have been introduced, all with the primary aim of more accurately targeting and treating cancerous tissues, leading to a precise, predictable and effective therapy technique. In this lecture series, we will review and describe some of the current developments in radiotherapy, particularly from the physics and technological view point, and will indicate in which direction future research in radiotherapy will lie. Our ultimate aim is to provide the student with a taste for the critical role that physics plays in this rapidly evolving discipline and to show that there is much interesting physics still to be done.
Inhalt	The lecture series will begin with a short introduction to radiotherapy and an overview of the lecture series (lecture 1). Lecture 2 will cover the medical imaging as applied to radiotherapy, without which it would be impossible to identify or accurately calculate the deposition of radiation in the patient. This will be followed by a detailed description of the treatment planning process, whereby the distribution of deposited energy within the tumour and patient can be accurately calculated, and the optimal treatment defined (lecture 3). Lecture 4 will follow on with this theme, but concentrating on the more theoretical and mathematical techniques that can be used to evaluate different treatments, using mathematically based biological models for predicting the outcome of treatments. The role of physics modeling, in order to accurately calculate the dose deposited from radiation in the patient, will be examined in lecture 5, together with a review of mathematical tools that can be used to optimize patient treatments. Lecture 6 will investigate a rather different issue, that is the standardization of data sets for radiotherapy and the importance of medical data bases in modern therapy. In lecture 7 we will look in some detail at one of the most advanced radiotherapy delivery techniques, namely Intensity Modulated Radiotherapy (IMRT). In lecture 8, the two topics of imaging and therapy will be somewhat combined, when we will describe the role of imaging in the daily set-up and assessment of patients. Lecture 9 follows up on this theme, in which a major problem of radiotherapy, namely organ motion and changes in patient and tumour geometry during therapy, will be addressed, together with methods for dealing with such problems. Finally, in lectures 10-11, we will describe in some of the multitude of different delivery techniques that are now available, including particle based therapy, rotational (tomo) therapy approaches and robot assisted radiotherapy. In the final lecture, we will provide an overview of the likely avenues of research in the next 5-10 years in radiotherapy. The course will be rounded-off with an opportunity to visit a modern radiotherapy unit, in order to see some of the techniques and delivery methods described in the course in action.
Voraussetzungen / Besonderes	Although this course is seen as being complimentary to the Medical Physics I and II course of Dr Manser, no previous knowledge of radiotherapy is necessarily expected or required for interested students who have not attended the other two courses.
465-0968-00L	Medizinphysik in der Praxis	W	2 KP	2V	P. Manser, Referent/innen
Kurzbeschreibung	Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen. Ein wichtiger Bestandteil ist dabei, den Dialog zwischen den Studierenden und den Praktikern zu fördern und Kontakte zu schaffen. Hierzu berichten verschiedene Dozenten aus der ganzen Schweiz über ihre Arbeit als Medizinphysiker.
Lernziel	Ziel der Vorlesung ist es, die verschiedenen Aspekte der Medizinischen Physik aus der Sicht des Praktikers kennenzulernen.
402-0787-00L	Therapeutic Applications of Particle Physics: Principles and Practice of Particle Therapy	W	6 KP	2V + 1U	A. J. Lomax
Kurzbeschreibung	Physics and medical physics aspects of particle physics Subjects: Physics interactions and beam characteristics; medical accelerators; beam delivery; pencil beam scanning; dosimetry and QA; treatment planning; precision and uncertainties; in-vivo dose verification; proton therapy biology.
Lernziel	The lecture series is focused on the physics and medical physics aspects of particle therapy. The radiotherapy of tumours using particles (particularly protons) is a rapidly expanding discipline, with many new proton and particle therapy facilities currently being planned and built throughout Europe. In this lecture series, we study in detail the physics background to particle therapy, starting from the fundamental physics interactions of particles with tissue, through to treatment delivery, treatment planning and in-vivo dose verification. The course is aimed at students with a good physics background and an interest in the application of physics to medicine.
Voraussetzungen / Besonderes	The former title of this course was "Medical Imaging and Therapeutic Applications of Particle Physics".
227-0384-00L	Ultrasound Fundamentals, Imaging, and Medical Applications Number of participants limited to 25.	W	4 KP	3G	O. Göksel
Kurzbeschreibung	Ultrasound is the only imaging modality that is nonionizing (safe), real-time, cost-effective, and portable, with many medical uses in diagnosis, intervention guidance, surgical navigation, and as a therapeutic option. In this course, we introduce conventional and prospective applications of ultrasound, starting with the fundamentals of ultrasound physics and imaging.
Lernziel	Students can use the fundamentals of ultrasound, to analyze and evaluate ultrasound imaging techniques and applications, in particular in the field of medicine, as well as to design and implement basic applications.
Inhalt	Ultrasound is used in wide range of products, from car parking sensors, to assessing fault lines in tram wheels. Medical imaging is the eye of the doctor into body; and ultrasound is the only imaging modality that is nonionizing (safe), real-time, cheap, and portable. Some of its medical uses include diagnosing breast and prostate cancer, guiding needle insertions/biopsies, screening for fetal anomalies, and monitoring cardiac arrhythmias. Ultrasound physically interacts with the tissue, and thus can also be used therapeutically, e.g., to deliver heat to treat tumors, break kidney stones, and targeted drug delivery. Recent years have seen several novel ultrasound techniques and applications – with many more waiting in the horizon to be discovered. This course covers ultrasonic equipment, physics of wave propagation, numerical methods for its simulation, image generation, beamforming (basic delay-and-sum and advanced methods), transducers (phased-, linear-, convex-arrays), near- and far-field effect, imaging modes (e.g., A-, M-, B-mode), Doppler and harmonic imaging, ultrasound signal processing techniques (e.g., filtering, time-gain-compensation, displacement tracking), image analysis techniques (deconvolution, real-time processing, tracking, segmentation, computer-assisted interventions), acoustic-radiation force, plane-wave imaging, contrast agents, micro-bubbles, elastography, biomechanical characterization, high-intensity focused ultrasound and therapy, lithotripsy, histotripsy, photo-acoustics phenomenon and opto-acoustic imaging, as well as sample non-medical applications such as the basics of non-destructive testing (NDT).
Voraussetzungen / Besonderes	Hands-on exercises will help apply concepts learned in the module, and will involve a mix of designing, implementing, and evaluating in simulation environments, such as Matlab FieldII and k-Wave toolboxes. Prerequisites: Familiarity with basic numerical methods. Basic programming skills and experience in Matlab.

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