Search result: Catalogue data in Autumn Semester 2022
Health Sciences and Technology Bachelor  | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Bachelor Studies (Programme Regulations 2020) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Core Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examinations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examinations Part 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 551-0033-00L | Molecular Genetics and Cell Biology  Only for Health Sciences and Technology BSc and Human Medicine BSc. | O | 5 credits | 5G | J. Corn, F. Allain, K. Köhler | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course teaches the basic principles of evolution, cell biology, molecular biology, genetics and developmental biology using the example of humans. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | 1) Students can explain the importance of evolution for the development of humans and diseases. 2) The students know the cell as the smallest unit of the body. They can explain how the functions of the cell are disturbed in certain diseases and where therapies intervene. They can describe the multiplication of cells in the body and show how errors in this multiplication can lead to diseases. 3) The students know DNA as the basis of life. They can explain how the DNA information is stored and how this information can be reproduced and protected from damage. They can describe how the information is read and translated into proteins. They can explain which mechanisms at the level of DNA, RNA and proteins can cause diseases. 4) Students can explain which technologies can be used to diagnose and treat diseases. 5) Students can explain how people differ genetically and know the molecular basis of these differences. They can explain how these differences can lead to diseases and why some of these differences do not affect diseases. 6) The students know the molecular causes of the most common hereditary diseases and can determine the probability of occurrence and transmission to offspring. 7) Students can explain the biochemical and molecular basis of human reproduction and know the basic principles of human embryonic development. The students can explain which mechanisms can be disturbed by a faulty development. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 529-1001-03L | General Chemistry (for HST) | O | 6 credits | 4V + 2U | J. Cvengros | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The course is designed to provide an understanding of the basic principles and concepts of general and inorganic chemistry. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Charles E. Mortimer, CHEMIE - DAS BASISWISSEN DER CHEMIE. 12. Auflage, Georg Thieme Verlag Stuttgart, 2015. Weiterführende Literatur: Theodore L. Brown, H. Eugene LeMay, Bruce E. Bursten, CHEMIE. 10. Auflage, Pearson Studium, 2011. (deutsch) Catherine Housecroft, Edwin Constable, CHEMISTRY: AN INTRODUCTION TO ORGANIC, INORGANIC AND PHYSICAL CHEMISTRY, 3. Auflage, Prentice Hall, 2005.(englisch) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 252-0852-00L | Foundations of Computer Science | O | 4 credits | 2V + 2U | L. E. Fässler, M. Dahinden | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Students learn to apply selected concepts and tools from computer science for working on interdisciplinary projects. The following topics are covered: modeling and simulations, introduction to programming, introduction matrices, managing data with lists and tables and with relational databases, universal methods for algorithm design. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The students learn to - understand the role of computer science in science, - to control computer and automate processes of problem solving by programming, - choose and apply appropriate tools from computer science, - process and analyze real-world data from their subject of study, - handle the complexity of real-world data. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | 1. The role of computer science in science 2. Introduction to Programming with Python 3. Modeling and simulations 4. Data management with lists and tables 5. Data management with a relational database 6. Introduction to Matrices | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | All materials for the lecture are available at www.gdi.ethz.ch | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | L. Fässler, M. Dahinden, D. Komm, and D. Sichau: Einführung in die Programmierung mit Python und Matlab. Begleitunterlagen zum Onlinekurs und zur Vorlesung, 2016. ISBN: 978-3741250842. L. Fässler, M. Dahinden, and D. Sichau: Verwaltung und Analyse digitaler Daten in der Wissenschaft. Begleitunterlagen zum Onlinekurs und zur Vorlesung, 2017. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | This course is based on application-oriented learning. The students spend most of their time working through projects with data from natural science and discussing their results with teaching assistants. To learn the computer science basics there are electronic tutorials available. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 376-0003-00L | Introduction to Health Sciences and Technology I | O | 4 credits | 2V + 2U | R. Müller | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Overview on various aspects of health and disease (health models, diagnostics and therapy of diseases, prevention, epidemiology); introduction to technical aspects (mechanics, measurement technique, control); fundamentals of scientific working (ethics, literature search, study design, data collection, data analysis and data presentation). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students should know the terms, models and classification systems used in health and disease; in addition, they should understand the methods of scientific working. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | - Health: health models, diagnostics, epidemiology, therapy, prevention. - Technology: mechanics, measurement technology, automatic control engineering. - Science: ethics, literature search, study design, tests, data analysis, data presentation | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| First Year Examinations Part 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 529-1011-00L | Organic Chemistry I (for Biol./Pharm.Sc./HST) | O | 4 credits | 4G | C. Thilgen | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Fundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Understanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Organic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Printed lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (https://moodle-app2.let.ethz.ch). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | · Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 Seiten). · Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 6. Aufl., Wiley-VCH, 2020. · Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 8th ed., W. H. Freeman & Company, 2018. · Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 12th ed., Wiley, 2016. · Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Berlin, 2017 (Korr. Nachdr. 2. Auflage 2013). · Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012. · Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson Studium, 2011. · Organic Chemistry. Paula Y. Bruice, 8th ed., Pearson, 2016. · Essential Organic Chemistry. Paula Y. Bruice, 3rd ed., Pearson, 2015. (Designed for a one-term course) · Organic Chemistry I as a Second Language – Translating the basic concepts (Taschenbuch mit Übungen: 400 Seiten). David R. Klein; 4th ed., Wiley, 2016. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The course consists of lectures (36 hours) and problem-solving lessons (20 hours, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 401-0291-00L | Mathematics I | O | 6 credits | 4V + 2U | E. W. Farkas | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Mathematics I/II is an introduction to one- and multidimensional calculus and linear algebra emphasizing on applications. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students understand mathematics as a language for modeling and as a tool for solving practical problems in natural sciences. Students can analyze models, describe solutions qualitatively or calculate them explicitly if need be. They can solve examples as well as their practical applications manually and using computer algebra systems. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | ## Eindimensionale diskrete Entwicklungen ## - linear, exponentiell, begrenzt, logistisch - Fixpunkte, diskrete Veränderungsrate - Folgen und Grenzwerte ## Funktionen in einer Variablen ## - Reproduktion, Fixpunkte - Periodizität - Stetigkeit ## Differentialrechnung (I) ## - Veränderungsrate/-geschwindigkeit - Differentialquotient und Ableitungsfunktion - Anwendungen der Ableitungsfunktion ## Integralrechnung (I) ## - Stammfunktionen - Integrationstechniken ## Gewöhnliche Differentialgleichungen (I) ## - Qualitative Beschreibung an Beispielen: Beschränkt, Logistisch, Gompertz - Stationäre Lösungen - Lineare DGL 1. Ordnung - Trennung der Variablen ## Lineare Algebra ## - Erste Arithmetische Aspekte - Matrizenrechnung - Eigenwerte / -vektoren - Quadratische LGS und Determinante | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | In Ergänzung zu den Vorlesungskapiteln der Lehrveranstaltungen fassen wir wichtige Sachverhalte, Formeln und weitere Ausführungen jeweils in einem Vademecum zusammen. Dabei gilt: * Die Skripte ersetzen nicht die Vorlesung und/oder die Übungen! * Ohne den Besuch der Lehrveranstaltungen verlieren die Ausführungen ihren Mehrwert. * Details entwickeln wir in den Vorlesungen und den Übungen, um die hier bestehenden Lücken zu schliessen. * Prüfungsrelevant ist, was wir in der Vorlesung und in den Übungen behandeln. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Siehe auch Lernmaterial > Literatur **L. Papula** Mathematik für Ingenieure und Naturwissenschaftler, 2 Bände; Springer Verlag Vieweg. Via ETHZ-Bibliothek: https://link.springer.com/book/10.1007/978-3-658-21746-4 https://link.springer.com/book/10.1007/978-3-658-07790-7 **Th. Wihler** Mathematik für Naturwissenschaften, 2 Bände: Einführung in die Analysis, Einführung in die Lineare Algebra; Haupt-Verlag Bern, UTB. **H. H. Storrer** Einführung in die mathematische Behandlung der Naturwissenschaften I; Birkhäuser. Via ETHZ-Bibliothek: https://link.springer.com/book/10.1007/978-3-0348-8598-0 **Ch. Blatter** Lineare Algebra; VDF auch als [pdf](<https://people.math.ethz.ch/~blatter/linalg.pdf>) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | ## Übungen und Prüfungen ## + Die Übungsaufgaben (inkl. Multiple-Choice) sind ein wichtiger Bestandteil der Lehrveranstaltung. + Es wird erwartet, dass Sie mindestens 75 % der wöchentlichen Serien bearbeiten und zur Korrektur einreichen. + Der Prüfungsstoff ist eine Auswahl von Themen aus Vorlesung und Übungen. Für eine erfolgreiche Prüfung ist die konzentrierte Bearbeitung der Aufgaben unerlässlich. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Second and Third Year Core Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Examination Blocks | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Examination Block A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0151-00L | Anatomy and Physiology I | O | 5 credits | 4V | D. P. Wolfer, K. De Bock, L. Slomianka, C. Spengler, M. Willecke | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Basic knowledge of the anatomy and physiology of tissues, of the embryonal and postnatal development, the sensory organs, the neuro-muscular system, the cardiovascular system and the respiratory system. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Basic knowledge of human anatomy and physiology and basics of clinical pathophysiology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The lecture series provides a short overview of human anatomy and physiology Anatomy and Physiology I (fall term): Basics of cytology, histology, embryology; nervous system, sensory organs, muscles, cardiovascular system, respiratory system Anatomy and Physiology II (spring term): digestive tract, endocrine organs, metabolism and thermoregulation, skin, blood and immune system, urinary system, circadian rhythm, reproductive organs, pregnancy and birth. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Requirements: 1st year, scientific part. Part of the course is read and checked in English. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 401-0293-00L | Mathematics III | O | 5 credits | 3V + 2U | A. Caspar, N. Hungerbühler | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Vertiefung der mehrdimensionalen Analysis mit Schwerpunkt in der Anwendung der partiellen Differentialgleichungen, Vertiefung der Linearen Algebra und Einführung in die Systemanalyse und Modellbildung. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Die Studierenden - verstehen Mathematik als Sprache zur Modellbildung und als Werkzeug zur Lösung angewandter Probleme in den Naturwissenschaften. - können anspruchsolle Modelle analysieren, Lösungen qualitativ beschreiben oder allenfalls explizit berechnen: diskret/kontinuierlich in Zeit, Ebene und Raum. - können Beispiele und konkrete arithmetische und geometrische Situationen aus Anwendungen mit Methoden der höheren Mathematik interpretieren und bearbeiten. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Einführung Modellbildung - SIR-Modelle: Ausbreitung von Krankheiten bei Epidemien - Pocken-Modell: Was ist der Effekt von Impfungen? Lineare Modelle - Vektorräume - Lösungsraum eines Linearen DGL-Systems - Diagonalisierbarkeit und Normalformen - Exponential einer Matrix Fourier-Reihen - Euklidische Vektorräume - Orthogonale Projektion - Anwendungen Nichtlineare Modelle - Stationäre Lösungen, Qualitative Aussagen - Mehrdimensionale Modelle: Räuber-Beute, Lotka-Volterra Partielle Differentialgleichungen: Vorgänge, die von Raum und Zeit anhängen - Einführung, Repetition, Beispiele - Fourier-Methoden: Wärmeleitung, Laplace, Wellengleichung, Filter, Computertomographie Laplace-Transformation - Definition und Notation - Rechenregeln - Anwendungsbeispiele | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Buch: "Mathematische Modellbildung in den Life Sciences", A. Caspar und N. Hungerbühler | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | - Buch: "Mathematische Modellbildung in den Life Sciences", A. Caspar und N. Hungerbühler - Blatter, C.: Lineare Algebra für Ingenieure, Chemiker und Naturwissenschafter. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Vorlesungen Mathematik I/II | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 401-0643-13L | Statistics II | O | 3 credits | 2V + 1U | J. Dambon | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Vertiefung von Statistikmethoden. Nach dem detailierten Fundament aus Statistik I liegt nun der Fokus auf konzeptueller Breite und konkreter Problemlösungsfähigkeit mit der Statistiksoftware R. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Nach diesem Kurs können Sie mit der Statistiksoftware R Daten einlesen, auf vielfältige Art verarbeiten und Grafiken für Berichte oder Vorträge exportieren. Sie verstehen die Konzepte von Methoden wie Lineare Regression (mit Faktoren, Interaktion, Modellwahl), ANOVA (1-weg, 2-weg), Chi-Quadrat-Test, Fisher-Test, GLMs, Mixed Models, Clustering, PCA und können diese mit der Statistiksoftware R in der Praxis umsetzen. Zudem kennen Sie die Grundprinzipien von gutem experimentellem Design und können bestehende Studien kritisch hinterfragen. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Examination Block B | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 402-0083-00L | Physics I | O | 4 credits | 3V + 1U | K. S. Kirch | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course is an introduction to classical physics, with special focus on applications in medicine. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Obtain an understanding of basic concepts in classical physics and their application (using mathematical pre-knowledge) to the solution of simple problems, including certain applications in medicine. Obtain an understanding of relevant quantities and of orders of magnitude. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | General introduction; Positron-Emission-Tomography as appetizer, including ionising radiation; kinematics of a point mass; dynamics of a point mass (Newton's axioms and forces); physical work, power and energy; conservation of linear and angular momentum; oscillations and waves; mechanics of a rigid body; fluid mechanics; introduction to electricity. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Will be distributed at the start of the semester. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | "Physik für Mediziner, Biologen, Pharmazeuten", von Alfred Trautwein, Uwe Kreibig, Jürgen Hüttermann; De Gruyter Verlag. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Voraussetzung Mathematik I+II (Studiengänge Gesundheitswissenschaften und Technologie bzw. Humanmedizin) / Mathematik-Lehrveranstaltungen des Basisjahres (Studiengänge Chemie, Chemieingenieurwissenschaften bzw. Interdisziplinäre Naturwissenschaften) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Examination Block C only offered in spring semester. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Individual Subjects and Laboratory Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0019-00L | Laboratory Course in Medical Technology Only for BSc HST students. Students from other degree programmes please contact: hcooper@ethz.ch | O | 2 credits | 2P | J. G. Snedeker | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This practical course is designed to give students hands on experience in CAD, FEM, product optimization, mechanical load testing, software development and hardware utilization in robotics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The course aims at teaching and solidifying following topics: CAD FEM Product optimization Mechanical testing Software development Hardware usage in robotics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The course is aimed at improving the students knowledge on certain topics such as programming in python and biomechanics, but also teaches new skills such as using CAD software, FEM and mechanical testing. The course is split into 6 sessions, which will be completed in groups. The students will be assigned to groups at the beginning of the semester. 4 of the experiments will be geared towards the use case of designing a bone plate to bridge a critical size gap of a femur. The experiments are therefore 1) using CAD to reconstruct the initial condition and the bone plate 2) running a FEM in order to analyze the performance of the bone plate 3) with the knowledge of the FEM, optimizing the bone plate and 4) testing of the designed bone plate, the bone plate will be 3D printed. The remaining 2 experiments will 1) focus on programming a robotic arm used in rehabilitation engineering and 2) on the hardware usage of the robotic arm including force sensors and EMG. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Each of the 6 sessions has its own tutorial and will be handed out to the students. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Only motivation and curiosity is required. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0002-01L | Product Design in Medical Engineering | O | 4 credits | 2V + 2U | S. J. Ferguson | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course will provide insight into various aspects of medical device design such as patient needs assessment, product specification, research and technical design, validation, regulatory affairs and clinical evaluation. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The goal of this lecture series is to enable the students to (i) identify the principal functional requirements for a medical device, (ii) to understand the mechanical properties of natural tissues and synthetic biomaterials, (iii) to apply this information and a basic knowledge of mechanics in the calculation of implant performance, (iv) to develop a plan for the pre-clinical evaluation and regulation of a new device. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | 1. Introduction to Medical Technology 2. Design Process 3. Mechanics 4. Mechanics of Materials 5. Tissue Mechanics 6. Prostheses: Biomechanics and Design 7. Prostheses: Biomaterials, Surfaces and Wear 8. Allografts: Heart Valves 9. Preclinical Evaluation 10. Regulatory Affairs (MepV, FDA, CE) 11. Intellectual Property 12. Group Work and Presentation | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | https://moodle-app2.let.ethz.ch/course/view.php?id=180 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Focus Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Human Movement Sciences and Sports | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0203-00L | Movement and Sport Biomechanics | W | 4 credits | 3G | W. R. Taylor, R. List | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Learning to view the human body as a (bio-) mechanical system. Making the connections between everyday movements and sports activity with injury, discomfort, prevention and rehabilitation. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students are able to describe the human body as a mechanical system. They analyse and describe human movement according to the laws of mechanics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Movement- and sports biomechanics deals with the attributes of the human body and their link to mechanics. The course includes topics such as functional anatomy, biomechanics of daily activities (gait, running, etc.) and looks at movement in sport from a mechanical point of view. Furthermore, simple reflections on the loading analysis of joints in various situations are discussed. Additionally, questions covering the statics and dynamics of rigid bodies, and inverse dynamics, relevant to biomechanics are investigated. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0207-00L | Exercise Physiology | W | 4 credits | 3G | C. Spengler, F. Gabe Beltrami | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course provides an overview over molecular and systemic aspects of neuromuscular, cardiovascular and respiratory adaptations to acute and chronic exercise as well as the interactions of the different systems influencing factors, e.g. genetics, gender, age, altitude/depth, heat/cold, with respect to performance and health. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The aim of this course is to understand molecular and systemic aspects of neuromuscular, cardiovascular and respiratory adaptations to acute and chronic exercise as well as the interaction of the different systems regarding health-relevant aspects and performance in healthy people and persons with selected diseases. Furthermore, students will understand the influence of genetics, gender, age, altitude/depth, heat and cold on the named factors. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | History of Exercise Physiology, research methods, fibertype heterogeneity and its functional significance, neural control of muscle force, molecular nad cellular mechanisms of muscle adaptation to resistance, endurance and stretching exercise, interindividual variability in the response to training, cardiorespiratory and metabolic responses to acute and chronic exercise, sexi differences relevant to exercise performance, exercise in hot and cold environment, children and adolescents in sport and exercise, exercise at altitude and depth, aging and exercise performance, exercise for health, exercise in the context of disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Online material is provided during the course. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Wird in der Vorlesung bekannt gegeben. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Anatomy and Physiology I + II | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-1220-00L | Rehabilitation and Inclusion | W | 3 credits | 2G | R. Riener | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course presents origins and prevention of different physical, sensory, mental impairments, their treatments, and methods of assistance in public and home environments. Rehabilitation is put into a larger context providing insights into healthcare systems, health economy, accessibility, barrier-free architecture, para-sports, legal & regulatory aspects, disability policy, and inclusion. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | With this lecture, we want to not only transfer a broad knowledge about rehabilitation and inclusion, but also raise awareness about the challenges and needs of people with impairments, the economy and the overall society. Students should learn about the complex and multi-facetted interaction of care, treatment, assistance, reimbursement, accessibility, legal regulation, and social inclusion. This knowledge and awareness should be presented in a multi-modal way using interactive tools and organizing group/plenar discussions. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The course will cover the following topics: • Introduction: definition of terms, historical and legal background, role of the UNO, WHO, ICRC • Origins: reasons and origins of physical, sensory and mental impairments; surgical and pharmaceutical treatments • Therapy: physical therapy, occupational therapy, speech therapy, psychotherapy • Technological support: Robot-aided therapy, Virtual Reality, muscle stimulation, Brain-Computer Interfaces (BCIs) • Home therapy: personal assistance, mobile health systems, tele-monitoring, tele-therapy • Assistive technologies: gait assistance, prosthesis, orthoses, seeing/hearing aids, etc. • Social inclusion: definition of normality and belongingness, social behaviours, UN-BRK, etc. • Accessibility: national and international aspects of accessibility • Health economy in rehabilitation: public and private cost models, health insurance, SUVA, IV • Barrier-free building and living: environmental obstacles, norms in architecture, inclusive design • Parasports: history of Olympics and Paralympics, Special Olympics, Deaflympics, Cybathlon • Policy: health, social, equal opportunity, disability • Regulatory affairs: ethics committees, Swissmedic, Bundesamt für Gesundheit (BAG), law and disability • Prevention: primary and secondary prevention, social prevention | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Medical Technology | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 227-0386-00L | Biomedical Engineering | W | 4 credits | 3G | J. Vörös, S. J. Ferguson, S. Kozerke, M. P. Wolf, M. Zenobi-Wong | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction into selected topics of biomedical engineering as well as their relationship with physics and physiology. The focus is on learning the basic vocabulary of biomedical engineering and getting familiar with concepts that govern common medical instruments and the most important organs from an engineering point of view. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Introduction into selected topics of biomedical engineering as well as their relationship with physics and physiology. The course provides an overview of the various topics of the different tracks of the biomedical engineering master course and helps orienting the students in selecting their specialized classes and project locations. It also serves as an introduction to the field for students of the ITET, MAVT, HEST and other bachelor programs. In addition, the most recent achievements and trends of the field of biomedical engineering are also outlined. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | History of BME and the role of biomedical engineers. Ethical issues related to BME. Biomedical sensors both wearable and also biochemical sensors. Bioelectronics: Nernst equation, Donnan equilibrium, equivalent circuits of biological membranes and bioelectronic devices. Bioinformatics: genomic and proteomic tools, databases and basic calculations. Equations describing basic reactions and enzyme kinetics. Medical optics: Optical components and systems used in hospitals. Basic concepts of tissue engineering and organ printing. Biomaterials and their medical applications. Function of the heart and the circulatory system. Transport and exchange of substances in the human body, compartment modeling. The respiratory system. Bioimaging. Orthopedic biomechanics. Lectures (2h), discussion of practical exercises (1h) and homework exercises. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Introduction to Biomedical Engineering by Enderle, Banchard, and Bronzino AND moodle page of the course | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | No specific requirements, BUT ITET, MAVT, PHYS students will have to learn a lot of new words related to biochemistry, biology and medicine, while HEST and BIOL students will have to grasp basic engineering concepts (circuits, equations, etc.). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Competencies |
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| 376-0021-00L | Materials and Mechanics in Medicine | W | 4 credits | 3G | M. Zenobi-Wong, J. G. Snedeker | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Understanding of physical and technical principles in biomechanics, biomaterials, and tissue engineering as well as a historical perspective. Mathematical description and problem solving. Knowledge of biomedical engineering applications in research and clinical practice. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Understanding of physical and technical principles in biomechanics, biomaterials, tissue engineering. Mathematical description and problem solving. Knowledge of biomedical engineering applications in research and clinical practice. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Biomaterials, Tissue Engineering, Tissue Biomechanics, Implants. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | course website on Moodle | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Introduction to Biomedical Engineering, 3rd Edition 2011, Autor: John Enderle, Joseph Bronzino, ISBN 9780123749796 Academic Press | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-1714-00L | Biocompatible Materials | W | 4 credits | 3V | K. Maniura, M. Rottmar, M. Zenobi-Wong | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction to molecules used for biomaterials, molecular interactions between different materials and biological systems (molecules, cells, tissues). The concept of biocompatibility is discussed and important techniques from biomaterials research and development are introduced. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The course covers the follwing topics: 1. Introdcution into molecular characteristics of molecules involved in the materials-to-biology interface. Molecular design of biomaterials. 2. The concept of biocompatibility. 3. Introduction into methodology used in biomaterials research and application. 4. Introduction to different material classes in use for medical applications. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Introduction into natural and polymeric biomaterials used for medical applications. The concepts of biocompatibility, biodegradation and the consequences of degradation products are discussed on the molecular level. Different classes of materials with respect to potential applications in tissue engineering, drug delivery and for medical devices are introduced. Strong focus lies on the molecular interactions between materials having very different bulk and/or surface chemistry with living cells, tissues and organs. In particular the interface between the materials surfaces and the eukaryotic cell surface and possible reactions of the cells with an implant material are elucidated. Techniques to design, produce and characterize materials in vitro as well as in vivo analysis of implanted and explanted materials are discussed. A link between academic research and industrial entrepreneurship is demonstrated by external guest speakers, who present their current research topics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Handouts are deposited online (moodle). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Literature: - Biomaterials Science: An Introduction to Materials in Medicine, Ratner B.D. et al, 3rd Edition, 2013 - Comprehensive Biomaterials, Ducheyne P. et al., 1st Edition, 2011 (available online via ETH library) Handouts and references therin. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-1220-00L | Rehabilitation and Inclusion | W | 3 credits | 2G | R. Riener | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course presents origins and prevention of different physical, sensory, mental impairments, their treatments, and methods of assistance in public and home environments. Rehabilitation is put into a larger context providing insights into healthcare systems, health economy, accessibility, barrier-free architecture, para-sports, legal & regulatory aspects, disability policy, and inclusion. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | With this lecture, we want to not only transfer a broad knowledge about rehabilitation and inclusion, but also raise awareness about the challenges and needs of people with impairments, the economy and the overall society. Students should learn about the complex and multi-facetted interaction of care, treatment, assistance, reimbursement, accessibility, legal regulation, and social inclusion. This knowledge and awareness should be presented in a multi-modal way using interactive tools and organizing group/plenar discussions. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The course will cover the following topics: • Introduction: definition of terms, historical and legal background, role of the UNO, WHO, ICRC • Origins: reasons and origins of physical, sensory and mental impairments; surgical and pharmaceutical treatments • Therapy: physical therapy, occupational therapy, speech therapy, psychotherapy • Technological support: Robot-aided therapy, Virtual Reality, muscle stimulation, Brain-Computer Interfaces (BCIs) • Home therapy: personal assistance, mobile health systems, tele-monitoring, tele-therapy • Assistive technologies: gait assistance, prosthesis, orthoses, seeing/hearing aids, etc. • Social inclusion: definition of normality and belongingness, social behaviours, UN-BRK, etc. • Accessibility: national and international aspects of accessibility • Health economy in rehabilitation: public and private cost models, health insurance, SUVA, IV • Barrier-free building and living: environmental obstacles, norms in architecture, inclusive design • Parasports: history of Olympics and Paralympics, Special Olympics, Deaflympics, Cybathlon • Policy: health, social, equal opportunity, disability • Regulatory affairs: ethics committees, Swissmedic, Bundesamt für Gesundheit (BAG), law and disability • Prevention: primary and secondary prevention, social prevention | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Health Sciences | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0309-00L | Concepts in Modern Genetics Information for UZH students: Enrolment to this course unit only possible at ETH. No enrolment to module BIO348 at UZH. Please mind the ETH enrolment deadlines for UZH students: Link | W | 6 credits | 4V | Y. Barral, D. Bopp, A. Hajnal, O. Voinnet | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Concepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | This course focuses on the concepts of classical and modern genetics and genomics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Scripts and additional material will be provided during the semester. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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