Suchergebnis: Katalogdaten im Herbstsemester 2019

Chemie- und Bioingenieurwissenschaften Master Information
Master-Studium (Studienreglement 2018)
Kernfächer
Bioverfahrenstechnik
NummerTitelTypECTSUmfangDozierende
529-0837-01LBiomicrofluidic Engineering Belegung eingeschränkt - Details anzeigen
Number of participants limited to 25.

IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GA. de Mello
KurzbeschreibungMicrofluidics describes the behaviour, control and manipulation of fluids that are geometrically constrained within sub-microliter environments. The use of microfluidic devices offers an opportunity to control physical and chemical processes with unrivalled precision, and in turn provides a route to performing chemistry and biology in an ultra-fast and high-efficiency manner.
LernzielIn the course students will investigate the theoretical concepts behind microfluidic device operation, the methods of microfluidic device manufacture and the application of microfluidic architectures to important problems faced in modern day chemical and biological analysis. A design workshop will allow students to develop new microscale flow processes by appreciating the dominant physics at the microscale. The application of these basic ideas will primarily focus on biological problems and will include a treatment of diagnostic devices for use at the point-of-care, advanced functional material synthesis, DNA analysis, proteomics and cell-based assays. Lectures, assignments and the design workshop will acquaint students with the state-of-the-art in applied microfluidics.
InhaltSpecific topics in the course include, but not limited to:

1. Theoretical Concepts
Features of mass and thermal transport on the microscale
Key scaling laws
2. Microfluidic Device Manufacture
Conventional lithographic processing of rigid materials
Soft lithographic processing of plastics and polymers
Mass fabrication of polymeric devices
3. Unit operations and functional components
Analytical separations (electrophoresis and chromatography)
Chemical and biological synthesis
Sample pre-treatment (filtration, SPE, pre-concentration)
Molecular detection
4. Design Workshop
Design of microfluidic architectures for PCR, distillation & mixing
5. Contemporary Applications in Biological Analysis
Microarrays
Cellular analyses (single cells, enzymatic assays, cell sorting)
Proteomics
6. System integration
Applications in radiochemistry, diagnostics and high-throughput experimentation
SkriptLecture handouts, background literature, problem sheets and notes will be provided electronically.
529-0615-01LBiochemical and Polymer Reaction Engineering
IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GP. Arosio
KurzbeschreibungPolymerization reactions and processes. Homogeneous and heterogeneous (emulsion) kinetics of free radical polymerization. Post treatment of polymer colloids. Bioprocesses for the production of molecules and therapeutic proteins. Kinetics and design of aggregation processes of macromolecules and proteins.
LernzielThe aim of the course is to learn how to design polymerization reactors and bioreactors to produce polymers and proteins with the specific product qualities that are required by different applications in chemical, pharmaceutical and food industry. This activity includes the post-treatment of polymer latexes, the downstream processing of proteins and the analysis of their colloidal behavior.
InhaltWe will cover the fundamental processes and the operation units involved in the production of polymeric materials and proteins. In particular, the following topics are discussed: Overview on the different polymerization processes. Kinetics of free-radical polymerization and use of population balance models. Production of polymers with controlled characteristics in terms of molecular weight distribution. Kinetics and control of emulsion polymerization. Surfactants and colloidal stability. Aggregation kinetics and aggregate structure in conditions of diffusion and reaction limited aggregation. Modeling and design of colloid aggregation processes. Physico-chemical characterization of proteins and description of enzymatic reactions. Operation units in bioprocessing: upstream, reactor design and downstream. Industrial production of therapeutic proteins. Characterization and engineering of protein aggregation. Protein aggregation in biology and in biotechnology as functional materials.
SkriptScripts are available on the web page of the Arosio-group: Link
Additional handout of slides will be provided during the lectures.
LiteraturR.J. Hunter, Foundations of Colloid Science, Oxford University Press, 2nd edition, 2001
D. Ramkrishna, Population Balances, Academic Press, 2000
H.W. Blanch, D. S. Clark, Biochemical Engineering, CRC Press, 1995
Produkte und Materialien
NummerTitelTypECTSUmfangDozierende
529-0619-01LChemical Product Design
Prerequisites: Basic chemistry and chemical engineering knowledge (Diffusion, Thermodynamics, Kinetics,...).

IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GW. J. Stark
KurzbeschreibungThe 'Chemical Product Design' course teaches students quantitative concepts to analyze, select and transform theoretical concepts from chemistry and engineering into valuable real-world products. Basic chemistry and chemical engineering knowledge is required (Diffusion, Thermodynamics, Kinetics, ..).
LernzielThis course starts with analyzing existing chemical needs and unmet technical challenges. We then develop the skills to critically analyze a specific chemical idea for a product, to rapidly test feasibility or chance for success and to eventually realize its manufacturing. The chemical engineering basics are then used to assess performance of products or devices with non-traditional functions based on dynamic properties (e.g. responsive building materials; personal medical diagnostics on paper strips). The course teaches the interface between laboratory and market with a specific focus on evaluating the chemical value of a given process or compound, and the necessary steps to pursue the resulting project within an entrepreneurial environment. We therefore extend the questions of process design ('how do we make something?') to the question of 'what should we make?
InhaltPart A: The 'Chemical Product Design' course starts with discussing questions along, 'What is a chemical product, and why do people pay for it? How does a given compound in a specific setting provide a service?' We then learn how to translate new, often ill-defined wishes or ideas into quantifiable specifications.

Part B: Thermodynamic and kinetic data allow sharp selection criteria for successful products. We learn how to deal with insufficient data and development of robust case models to evaluate their technical and financial constraints. How can parameters of a running process in one industry be scaled into another industry? Can dimensionless engineering numbers be applied beyond traditional chemical processes?

Part C: Manufacturing of commodity products, devices and molecular products: Chemical reactors, separation and detection or isolation units as part of a toolbox. Planning of manufacturing and decisions based on hard data. Providing quantitative answers on potential value generated.

Students are expected to actively develop chemical products along the course. Contributions will be made individually, or in small groups, where a larger topic is studied.
LiteraturCussler, E.L., Moggridge, C.D., Chemical Product Design, Cambridge University Press, Cambridge, UK, 2nd edition, 2011.

Original Literature: Issues and Trends in the Teaching of Process and Product Design, Biegler, L.T., Grossmann, I.E., Westerber, A.W., AIChE J., 56 (5) 1120-25, 2010.
Prozessentwurf
NummerTitelTypECTSUmfangDozierende
529-0643-01LProcess Design and Development Information
IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GG. Storti
KurzbeschreibungThe course is focused on the design of Chemical Processes, with emphasis on the preliminary stage of the design approach, where process creation and quick selection among many alternatives are important. The main concepts behind more detailed process design and process simulation are also examined in the last part of the course.
LernzielThe course is focused on the design of Chemical Processes, with emphasis on the preliminary stage of the design approach, where process creation and quick selection among many alternatives are important. The main concepts behind more detailed process design and process simulation are also examined in the last part of the course.
InhaltProcess creation: decomposition strategies (reduction of differences - vinyl chloride production and hierarchical decomposition - ethanol production). Identification of the "base case design". Heuristics for process synthesis.
Preliminary process evaluation: simplified material and energy balances (linear balances), degrees of freedom, short-cut models, flowsheet solution algorithm).
Process Integration: sequencing of distillation columns, synthesis of heat exchanger networks.
Process economic evaluation: equipment sizing and costing, time value of money, cash flow calculations.
Batch Processes: scheduling, sizing and inventories.
Detailed Process Design: unit operation models, flash solution algorithms (different iterative methods, inside-out method), sequencing of nonideal distillation columns, networks of chemical reactors.
Skriptno script
LiteraturL.T.Biegler et al., Systematic Methods of Chemical Process Design, Prentice Hall, 1997.
W.D.Seider et al., Process Design Principles, J. Wiley & Sons, 1998.
J.M.Douglas, Conceptual Design of Chemical Processes, McGraw-Hill, 1988.
Voraussetzungen / BesonderesPrerequisite: Thermal Unit Operations
529-0613-01LProcess Simulation and Flowsheeting
IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GG. Guillén Gosálbez
KurzbeschreibungThis course encompasses the theoretical principles of chemical process simulation, as well as its practical application in process analysis and optimization. The techniques for simulating stationary and dynamic processes are presented, and illustrated with case studies. Commercial software packages are presented as a key engineering tool for solving process flowsheeting and simulation problems.
LernzielThis course aims to develop the competency of chemical engineers in process flowsheeting and simulation. Specifically, students will develop the following skills:
- Deep understanding of chemical engineering fundamentals: the acquisition of new concepts and the application of previous knowledge in the area of chemical process systems and their mechanisms are crucial to intelligently simulate and evaluate processes.
- Modeling of general chemical processes and systems: students have to be able to identify the boundaries of the system to be studied and develop the set of relevant mathematical relations, which describe the process behavior.
- Mathematical reasoning and computational skills: the familiarization with mathematical algorithms and computational tools is essential to be capable of achieving rapid and reliable solutions to simulation and optimization problems. Hence, students will learn the mathematical principles necessary for process simulation and optimization, as well as the structure and application of process simulation software. Thus, they will be able develop criteria to correctly use commercial software packages and critically evaluate their results.
InhaltOverview of process simulation and flowsheeting
- Definition and fundamentals
- Fields of application
- Case studies

Process simulation
- Modeling strategies of process systems
- Mass and energy balances and degrees of freedom of process units and process systems

Process flowsheeting
- Flowsheet partitioning and tearing
- Solution methods for process flowsheeting
- Simultaneous methods
- Sequential methods

Process optimization and analysis
- Classification of optimization problems
- Linear programming
- Non-linear programming
- Optimization methods in process flowsheeting

Commercial software for simulation: Aspen Plus
- Thermodynamic property methods
- Reaction and reactors
- Separation / columns
- Convergence, optimisation & debugging
LiteraturAn exemplary literature list is provided below:
- Biegler, L.T., Grossmann I.E., Westerberg A.W., 1997, systematic methods of chemical process design. Prentice Hall, Upper Saddle River, US.
- Boyadjiev, C., 2010, Theoretical chemical engineering: modeling and simulation. Springer Verlag, Berlin, Germany.
- Ingham, J., Dunn, I.J., Heinzle, E., Prenosil, J.E., Snape, J.B., 2007, Chemical engineering dynamics: an introduction to modelling and computer simulation. John Wiley & Sons, United States.
- Reklaitis, G.V., 1983, Introduction to material and energy balances. John Wiley & Sons, United States.
Voraussetzungen / BesonderesA basic understanding of material and energy balances, thermodynamic property methods and typical unit operations (e.g., reactors, flash separations, distillation/absorption columns etc.) is required.
Katalyse und Separation
NummerTitelTypECTSUmfangDozierende
151-0927-00LRate-Controlled Separations in Fine ChemistryW+6 KP3V + 1UM. Mazzotti
KurzbeschreibungDie Studenten sollen einen vertieften Einblick in die Grundlagen der Trennverfahren erhalten, die in modernen Life Sciences Prozessen - spez. Feinchemie und Biotechnologie - zur Anwendung kommen.
LernzielDie Studenten sollen einen vertieften Einblick in die Grundlagen der Trennverfahren erhalten, die in modernen Life Sciences Prozessen - spez. Feinchemie und Biotechnologie - zur Anwendung kommen.
InhaltThe class covers separation techniques that are central in the purification and downstream processing of chemicals and bio-pharmaceuticals. Examples from both areas illustrate the utility of the methods: 1) Liquid-liquid extraction; 2) Adsorption and chromatography; 3) Membrane processes; 4) Crystallization and precipitation.
SkriptBeilagen in der Vorlesung
LiteraturBücher werden in der Vorlesung besprochen
Voraussetzungen / BesonderesBesonderes: Teile der Vorlesung werden in Englisch gehalten.

Voraussetzungen: Thermische Verfahrenstechnik I (151-0926-00) und Mathematische Methoden in den Chemieingenieurwissenschaften (151-0940-00)
529-0617-01LCatalysis Engineering
IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.
W+6 KP3GJ. Pérez-Ramírez, S. J. Mitchell
KurzbeschreibungThe purpose of the "Catalysis Engineering" course is to provide students with tools that enable the optimal design of catalytic materials and reactor engineering concepts favoring more sustainable manufacturing processes within the chemical industry.
LernzielThe course aims at illustrating, from conception to implementation, the design of sustainable catalytic processes by integration of the microlevel (catalyst), mesolevel (reactor), and macrolevel (process). The word "sustainable" implies intensified processes with an improved exploitation of raw materials, wider use of renewable feedstocks, reduction of energy consumption, and minimized environmental impact. By the use of modern case studies of industrial relevance, aspects of catalyst preparation and characterization, kinetics, mass and heat transport, and deactivation are discussed. Emphasis is put on understanding the interaction among these basic elements in order to select the optimal catalytic process. Since no textbooks covering this area are available at this time and the intention of this course is unique, the lectures will be based on own texts and journal articles. During the course, there will be specific topics addressed by industrial contributors.
InhaltThe following general aspects:

- Catalyst preparation and characterization
- Kinetics
- Mass and heat transport
- Selectivity
- Deactivation

will be demonstrated for modern catalytic materials and processes of industrial relevance such as:

- Chlorine recycling
- N2O abatement
- Chemoselective hydrogenations
- Hierarchical zeolite catalysts
- Syngas conversion
- Biomass to chemicals and fuels
SkriptThe course material is based on an own script, journal articles, and slides.
Voraussetzungen / BesonderesIt is assumed that students selecting this course are familiar with general concepts of catalysis, reactor design, and transport phenomena.
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