The course comprises experiments relating to concepts of medicinal chemistry including statistical processing, fitting of experimental data, computer modeling of protein structures, experimental measurement of affinity constants and kinetic dissociation constants for protein ligands. The chemical stability of a drug will be studied. Basic gene cloning and protein expression will be introduced.
Learning objective
Knowledge of experimental methods in drug discovery and development
Content
Characterisation of the biophysical and biological properties of drugs.
Lecture notes
Scripts
Literature
Original literature
Prerequisites / Notice
Requirements: Laboratory course in Pharmaceutical Anaytics; Lecture Medicinal Chemistry I in the same semester or earlier.
