529-0459-01L  Case Studies in Process Design

SemesterAutumn Semester 2023
LecturersG. Guillén Gosálbez
Periodicityyearly recurring course
Language of instructionEnglish


529-0459-01 ACase Studies in Process Design
This course does not take place on a weekly basis. Instead, a case study is carried out by the students in a specific "case study week" from 13.11 to 17.11

42s hrsG. Guillén Gosálbez

Catalogue data

AbstractThe learning objective is to design, simulate and optimize a real (bio-)chemical process from a process systems perspective. Specifically, a commercial process simulation software (Aspen) will be used for the process simulation and optimization. Students have to integrate knowledge and develop engineering thinking and skills acquired in the other courses of the curriculum.
ObjectiveSimulate and optimize a chemical production process using commercial process simulation software.
ContentCreate a model describing the production process
- Students will apply a commercial process simulator systematically for process creation and analysis.
- Students will create a process simulation flowsheet for steady-state simulation.

Evaluate the performance of the production process
- Students will analyse and understand the degrees of freedom in modelling process units and flowsheets.
- Students will understand the role of process simulators in process creation.
- Students will make design specifications and follow the iterations implemented to satisfy them.
- Students will judge the role of process simulators in equipment sizing and costing and profitability analysis.
- Students will assess the economic performance of the process, including operating costs (OPEX), and capital investment (CAPEX), based on the outcome of the simulation model.
- Students will assess the environmental impact of the production process following the Life Cycle Assessment (LCA) methodology.

Optimize the design and operating conditions of the production process
- Students will carry out sensitivity analyses and optimizations considering technical and economic criteria.
- Students will generate process integration alternatives to improve the initial design.
- Students will optimize the production process considering economic and environmental criteria.
Prerequisites / NoticeBefore the case study week, students are encouraged to participate in the exercises of the course "Process Simulation and Flowsheeting" in order to get familiar with the Aspen Plus simulation software (this is highly recommended, but not mandatory).
The problem statement and detailed instructions are provided in the project brief made available at the beginning of the case study week.

During the case study week:
- Students work in teams of 4-6 people.
- Students have to pose and solve process equipment and system design related problems.
- Students have to coordinate the activities, the preparation of the written report and the oral presentation.
- Students get support from project assistants and the course supervisor.

The groups deliver the written report on a predefined date.

The students receive the feedback and are asked to implement some changes in their reports.

A final presentation takes place summarizing the main findings of the project.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits3 credits
ExaminersG. Guillén Gosálbez
Typeungraded semester performance
Language of examinationEnglish
RepetitionRepetition only possible after re-enrolling for the course unit.
Admission requirementThe performance assessment is based on one report of the project and a presentation of the main results. The mark is either pass or fail.
Additional information on mode of examinationThe performance assessment is based on one report of the project and a presentation of the main results. The mark is either pass or fail.

Learning materials

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Only public learning materials are listed.


No information on groups available.


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Offered in

Chemical and Bioengineering MasterCase StudyOInformation