529-0042-00L  Structure Elucidation by NMR

SemesterSpring Semester 2023
LecturersM.‑O. Ebert
Periodicityyearly recurring course
Language of instructionEnglish


529-0042-00 GStructure Elucidation by NMR2 hrs
Tue09:45-11:30HIL C 10.2 »
M.‑O. Ebert

Catalogue data

AbstractStructure Elucidation of Complex Organic Molecules by NMR
ObjectiveStructure elucidation of complex organic molecules (including peptides, oligosaccharides and oligonucleotides) by advanced 1D and 2D NMR spectroscopy: Finding the constitution, rel. configuration and the conformation of an unkown molecule. The emphasis of the course is on the selection of optimal strategies for the solution of a given problem. Discussing and solving these problems by the combined application of various 2D methods form an important part of the course. This also includes the use of state-of-the-art methods for computer assisted structure elucdation (CASE) and chemical shift prediction.
ContentImportant experiments for structure elucidation. Finding the optimal strategy for a given problem. Spectral processing for optimal results. Spectral interpretation. Assignment strategies for complex molecules. Common Artefacts. Computer assisted structure elucidation incl. introduction to relevant software and hands-on application. Chemical shift prediction. Discussion of challenging problem sets during class.
Lecture notesScripts (in English) are distributed in the course
Literature"T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistryî, Pergamon Press, 1999. (NMR Teil)

Further reading and citations are listed in the script.
Prerequisites / NoticeThe course language is English.
Required level:
Courses in analytical chemistry of the 2nd year or equivalent.
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Media and Digital Technologiesfostered
Personal CompetenciesCreative Thinkingfostered
Critical Thinkingfostered

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersM.-O. Ebert
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationwritten 60 minutes
Additional information on mode of examinationSchriftliche Prüfung auf Englisch, Antwort auf Deutsch möglich.
Written aidsAlle, ausser Telekommunikation und Computer, Taschenrechner erlaubt
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

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Offered in

Biochemistry – Chemical Biology BachelorElectivesWInformation
Chemistry BachelorAnalytical ChemistryWInformation
Chemistry MasterAnalytical ChemistryWInformation
Doctorate Chemistry and Applied BiosciencesOrganic ChemistryWInformation