Kurzbeschreibung | Principles and technologies for the manufacturing of dosage forms and drug delivery systems. Knowledge of pharmaceutical excipients, materials, containers, liquid, solid and semi-solid dosage forms, their production, function, quality and application. |
Lernziel | Knowledge of the most important pharmaceutical excipients, materials, containers, liquid, solid and semi-solid dosage forms, of their production, function, quality, stability and application. Comprehension of the molecular interactions in solid state, solution and colloidal systems. |
Inhalt | Introduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. Overview of the most important pharmaceutical excipients and polymers, their structure, properties and processing; importance of materials properties for containers. Pharmaceutical solvents, fundamentals of solubility and solubilization of drugs. Water treatment processes, sterilization techniques and quality requirements of pharmaceutical water. Parenteral dosage forms and liquid ophthalmics. Surfactants, micelle formation and colloidal systems. Liquid suspensions and emulsions. Stabilization measures in dosage forms. Important fundamentals, principles and technologies for the development and manufacturing of solid dosage forms and drug delivery systems. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration. |
Literatur | M. E. Aulton and K. M. G. Taylor, Aulton's Pharmaceutics: The design and manufacture of medicines, 6th ed, Elsevier, Edinburgh, 2021. (excepting chapters 7, 13, 14, 19, 22, 25, 46, 47 and 48 and 49) |
Kompetenzen | Fachspezifische Kompetenzen | Konzepte und Theorien | geprüft | | Verfahren und Technologien | geprüft | Methodenspezifische Kompetenzen | Analytische Kompetenzen | geprüft | | Entscheidungsfindung | geprüft | | Medien und digitale Technologien | gefördert | | Problemlösung | geprüft | | Projektmanagement | gefördert | Soziale Kompetenzen | Kommunikation | gefördert | | Kooperation und Teamarbeit | gefördert | | Kundenorientierung | geprüft | | Menschenführung und Verantwortung | gefördert | | Selbstdarstellung und soziale Einflussnahme | gefördert | | Sensibilität für Vielfalt | geprüft | | Verhandlung | gefördert | Persönliche Kompetenzen | Anpassung und Flexibilität | geprüft | | Kreatives Denken | gefördert | | Kritisches Denken | geprüft | | Integrität und Arbeitsethik | gefördert | | Selbstbewusstsein und Selbstreflexion | gefördert | | Selbststeuerung und Selbstmanagement | gefördert |
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