227-0385-10L  Biomedical Imaging

SemesterAutumn Semester 2022
LecturersS. Kozerke, K. P. Prüssmann
Periodicityyearly recurring course
Language of instructionEnglish

AbstractIntroduction to diagnostic medical imaging based on electromagnetic and acoustic fields including X-ray planar and tomographic imaging, radio-tracer based nuclear imaging techniques, magnetic resonance imaging and ultrasound-based procedures.
ObjectiveUpon completion of the course students are able to:

• Explain the physical and mathematical foundations of diagnostic medical imaging systems
• Characterize system performance based on signal-to-noise ratio, contrast-to-noise ratio and transfer function
• Design a basic diagnostic imaging system chain including data acquisition and data reconstruction
• Identify advantages and limitations of different imaging methods in relation to medical diagnostic applications
Content• Introduction (intro, overview, history)
• Signal theory and processing (foundations, transforms, filtering, signal-to-noise ratio)
• X-rays (production, tissue interaction, contrast, modular transfer function)
• X-rays (resolution, detection, digital subtraction angiography, Radon transform)
• X-rays (filtered back-projection, spiral computed tomography, image quality, dose)
• Nuclear imaging (radioactive tracer, collimation, point spread function, SPECT/PET)
• Nuclear imaging (detection principles, image reconstruction, kinetic modelling)
• Magnetic Resonance (magnetic moment, spin transitions, excitation, relaxation, detection)
• Magnetic Resonance (plane wave encoding, Fourier reconstruction, pulse sequences)
• Magnetic Resonance (contrast mechanisms, gradient- and spin-echo, applications)
• Ultrasound (mechanical wave generation, propagation in tissue, reflection, transmission)
• Ultrasound (spatial and temporal resolution, phased arrays)
• Ultrasound (Doppler shift, implementations, applications)
• Summary, example exam questions
Lecture notesLecture notes and handouts
LiteratureWebb A, Smith N.B. Introduction to Medical Imaging: Physics, Engineering and Clinical Applications; Cambridge University Press 2011
Prerequisites / NoticeAnalysis, Linear algebra, Physics, Basics of signal theory, Basic skills in Matlab/Python programming
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Media and Digital Technologiesfostered
Social CompetenciesCommunicationassessed
Cooperation and Teamworkassessed
Personal CompetenciesAdaptability and Flexibilityfostered
Creative Thinkingassessed
Critical Thinkingassessed
Integrity and Work Ethicsfostered
Self-direction and Self-management fostered