376-1348-00L  Cellular Ageing

SemesterAutumn Semester 2022
LecturersG. Shivashankar
Periodicityyearly recurring course
Language of instructionEnglish



Courses

NumberTitleHoursLecturers
376-1348-00 VCellular Ageing2 hrs
Wed15:45-17:30HIL E 1 »
G. Shivashankar

Catalogue data

AbstractCells undergo major functional alterations as we age. In this course, we will discuss the basic molecular and cell biological mechanisms of cellular ageing. We will also discuss diseases related to cellular ageing and current rejuvenation and therapeutic strategies for cellular ageing in health and disease.
Objective- Basic molecular and cell biological mechanisms of cellular ageing;
- Diseases related to cellular ageing;
- current rejuvenation and therapeutic strategies for cellular ageing in health and disease.
ContentLecture-1: Hallmarks of cellular ageing
Lecture-2: Cellular microenvironment & extra-cellular matrix
Lecture-3: Cell morphometric changes & cytoskeletal remodeling
Lecture-4: Proteostasis
Lecture-5: Mitochondrial dysfunction
Lecture-6: Endo-membrane signaling
Lecture-7: Nuclear signaling & epigenetic alternations
Lecture-8: Chromatin remodeling & gene expression
Lecture-9: Genomic integrity
Lecture-10: Ageing cell secretome and cellular homeostasis
Lecture-11: Diseases associated with cellular ageing
Lecture-12: Cellular rejuvenation strategies
Lecture-13: Therapeutic interventions to cellular ageing
Lecture-14: Concluding lecture

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits3 credits
ExaminersG. Shivashankar
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationwritten 60 minutes
Additional information on mode of examinationGrading consists of
- compulsory class presentations graded 1-6 and counting 50% towards the final grade.
- final exam counting 50% towards the final grade.
The examination may be conducted as a computer examination.
Written aidsNone
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

Learning materials

No public learning materials available.
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
Health Sciences and Technology BachelorMolecular Health SciencesWInformation
Health Sciences and Technology BachelorMolecular Health SciencesWInformation