551-1129-00L  Understanding and Engineering Microbial Metabolism

SemesterAutumn Semester 2022
LecturersJ. Vorholt-Zambelli
Periodicityyearly recurring course
Language of instructionEnglish
CommentNumber of participants limited to 6.
The enrolment is done by the D-BIOL study administration.


551-1129-00 PUnderstanding and Engineering Microbial Metabolism
Permission from lecturers required for all students.
Block course in the 1st quarter of the autumn semester
100s hrs
Tue12:45-16:30HCI F 436 »
Wed/107:45-16:30HCI F 436 »
Thu/107:45-16:30HCI F 436 »
Fri/107:45-16:30HCI F 436 »
J. Vorholt-Zambelli

Catalogue data

AbstractThis laboratory course has a focus on current research topics in our laboratory related to metabolic engineering, the general understanding of metabolism, and is partially focused on one carbon metabolism. Projects will be conducted in small groups.
ObjectiveThe course aims at introducing technologies to investigate bacterial metabolism and key principles of metabolic engineering. The main focus of this block course is on practical work and will familiarize participants with complementary approaches, in particular genetic, biochemical and analytical techniques including metabolomics. Results will be presented by students in scientific presentations. Another goal is to learn how to write a scientific report.
ContentThe course and will include topics such as pathway elucidation & engineering and related ongoing research projects in the lab. Experimental work applied during the course will comprise methods such as cloning work & transformation, growth determination, enzyme activity assays, liquid-chromatography mass-spectrometry and dynamic labeling experiments.
Lecture notesNone
LiteratureWill be provided at the beginning of the course.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits6 credits
ExaminersJ. Vorholt-Zambelli
Typegraded semester performance
Language of examinationEnglish
RepetitionRepetition only possible after re-enrolling for the course unit.
Additional information on mode of examinationStudent evaluations will be based on an exam, a project presentation and a written report.
Details will be communicated at the beginning of the course.

Students are obliged to be present throughout the block course.
Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC to Link) so that the enrollment is deleted. Otherwise the course is considered as "failed".

Learning materials

Moodle courseMoodle-Kurs / Moodle course
Only public learning materials are listed.


No information on groups available.


GeneralPermission from lecturers required for all students

Offered in

Biochemistry – Chemical Biology BachelorBlock courses in the 1st quarter of the semesterWInformation
Biology BachelorBlock Courses in 1st Quarter of the SemesterWInformation
Biology BachelorBlock Courses in 1st Quarter of the SemesterWInformation