529-0042-00L  Structure Elucidation by NMR

SemesterSpring Semester 2022
LecturersM.‑O. Ebert
Periodicityyearly recurring course
Language of instructionEnglish


529-0042-00 GStructure Elucidation by NMR2 hrs
Tue07:45-09:30HCI D 2 »
M.‑O. Ebert

Catalogue data

AbstractStructure Elucidation of Complex Organic Molecules by NMR
ObjectiveStructure elucidation of complex organic molecules (including peptides, oligosaccharides and oligonucleotides) by advanced 1D and 2D NMR spectroscopy. The emphasis of the course is on the selection of optimal strategies for the solution of a given problem, spectrum interpretation and possible artifacts. Solving and discussing practical case studies/problems demonstrating the individual methods and, in the last third of the course, the combined application of several methods form an important part of the course.
ContentStructure determination by multi-pulse and 2D NMR spectroscopy. Homonuclear and heteronuclear shift correlation through scalar coupling; one and two dimensional methods based on the nuclear Overhauser effect. Choosing the best strategy for a given problem, interpretation and artefacts.
Lecture notesScripts (in English) are distributed in the course
Literature"T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistryî, Pergamon Press, 1999. (NMR Teil)

Further reading and citations are listed in the script.
Prerequisites / NoticeThe course language is English.
Required level:
Courses in analytical chemistry of the 2nd year or equivalent.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersM.-O. Ebert
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationwritten 60 minutes
Additional information on mode of examinationSchriftliche Prüfung auf Englisch, Antwort auf Deutsch möglich.
Written aidsAlle, ausser Telekommunikation und Computer, Taschenrechner erlaubt
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

Learning materials

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Offered in

Chemistry BachelorAnalytical ChemistryWInformation
Chemistry MasterAnalytical ChemistryWInformation
Doctorate Chemistry and Applied BiosciencesOrganic ChemistryWInformation