636-0009-00L  Evolutionary Dynamics

SemesterHerbstsemester 2021
DozierendeN. Beerenwinkel
Periodizitätjährlich wiederkehrende Veranstaltung
LehrspracheEnglisch



Lehrveranstaltungen

NummerTitelUmfangDozierende
636-0009-00 VEvolutionary Dynamics
Attention: lecture starts on Thursday, 30 Sep 2021

Online lecture: This lecture will primarily take place online. Reserved rooms will remain blocked for students to follow the course from there.
2 Std.
Do09:15-11:00BSA E 46 »
09:15-11:00HG D 16.2 »
N. Beerenwinkel
636-0009-00 UEvolutionary Dynamics
Online: Will primarily take place online. Reserved rooms will remain blocked on campus for students to follow the course from there
1 Std.
Do11:15-12:00BSA E 46 »
11:15-12:00HG D 16.2 »
N. Beerenwinkel
636-0009-00 AEvolutionary Dynamics
Project Work (compulsory continuous performance assessment), no fixed presence required.
2 Std.N. Beerenwinkel

Katalogdaten

KurzbeschreibungEvolutionary dynamics is concerned with the mathematical principles according to which life has evolved. This course offers an introduction to mathematical modeling of evolution, including deterministic and stochastic models, with an emphasis on tumor evolution.
LernzielThe goal of this course is to understand and to appreciate mathematical models and computational methods that provide insight into the evolutionary process in general and tumor evolution in particular. Students should analyze and evaluate models and their application critically and be able to design new models.
InhaltEvolution is the one theory that encompasses all of biology. It provides a single, unifying concept to understand the living systems that we observe today. We will introduce several types of mathematical models of evolution to describe gene frequency changes over time in the context of different biological systems, focusing on asexual populations. Viruses and cancer cells provide the most prominent examples of such systems and they are at the same time of great biomedical interest. The course will cover some classical mathematical population genetics and population dynamics, and also introduce several new approaches. This is reflected in a diverse set of mathematical concepts which make their appearance throughout the course, all of which are introduced from scratch. Topics covered include the quasispecies equation, evolution of HIV, evolutionary game theory, evolutionary stability, evolutionary graph theory, tumor evolution, stochastic tunneling, genetic progression of cancer, diffusion theory, fitness landscapes, branching processes, and evolutionary escape.
SkriptNo.
Literatur- Evolutionary Dynamics. Martin A. Nowak. The Belknap Press of Harvard University Press, 2006.
- Evolutionary Theory: Mathematical and Conceptual Foundations. Sean H. Rice. Sinauer Associates, Inc., 2004.
Voraussetzungen / BesonderesPrerequisites: Basic mathematics (linear algebra, calculus, probability)
KompetenzenKompetenzen
Fachspezifische KompetenzenKonzepte und Theoriengeprüft
Methodenspezifische KompetenzenAnalytische Kompetenzengeprüft
Problemlösunggeprüft
Soziale KompetenzenKommunikationgefördert
Kooperation und Teamarbeitgefördert
Persönliche KompetenzenKritisches Denkengeprüft
Selbststeuerung und Selbstmanagement gefördert

Leistungskontrolle

Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird)
Leistungskontrolle als Semesterkurs
ECTS Kreditpunkte6 KP
PrüfendeN. Beerenwinkel
FormSessionsprüfung
PrüfungsspracheEnglisch
RepetitionDie Leistungskontrolle wird in jeder Session angeboten. Die Repetition ist ohne erneute Belegung der Lerneinheit möglich.
Prüfungsmodusmündlich 15 Minuten
Zusatzinformation zum PrüfungsmodusRepetition possible only with re-enrollment, including projects.
The final grade is 70% oral session examination and 30% project. The practical projects are compulsory continuous performance assessments (60 hours of work, 2 credits) of the course. The project has to be re-run in case of a repetition.
Diese Angaben können noch zu Semesterbeginn aktualisiert werden; verbindlich sind die Angaben auf dem Prüfungsplan.

Lernmaterialien

Keine öffentlichen Lernmaterialien verfügbar.
Es werden nur die öffentlichen Lernmaterialien aufgeführt.

Gruppen

Keine Informationen zu Gruppen vorhanden.

Einschränkungen

Keine zusätzlichen Belegungseinschränkungen vorhanden.

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