636-0550-00L  Biomolecular Nanotechnology

SemesterAutumn Semester 2021
LecturersM. Nash
Periodicityyearly recurring course
Language of instructionEnglish


636-0550-00 VBiomolecular Nanotechnology
Wednesdays 08.00-10.00 Campus Rosental 1095, Conference room E00.012
ATTENTION: This lecture will start on Wednesday, Sept. 29
2 hrsM. Nash
636-0550-00 UBiomolecular Nanotechnology
Thursday, 08.00-09.00 Campus Rosental 1060, Seminar room 2.14
ATTENTION: The first tutorial will take place on Thursday, Sept. 30
1 hrsM. Nash

Catalogue data

AbstractBiomolecular nanotechnology is a broad field that focuses on the study and science of biological materials including DNA, RNA and proteins at length scales below 10 nm. This is a broad overview of the topic with a focus on current research themes.
ObjectiveThe objective is to familiarise the students with a broad range of topics related to biotechnology, nanotechnology, and biophysics with a focus on current research and reading of scientific literature.
ContentIntroduction to biomacromolecules; Measurement techniques for characterisation of biomacromolecules; Fundamentals of molecular recognition; Recombinant DNA; Protein engineering; Directed evolution; Protein folding; Polymers; Elastin-like polypeptides; Intelligent materials; Spatially localized hydrogels; Mechanical properties of proteins and macromolecules; Single-molecule force spectroscopy
LiteratureRepresentative literature:
(1) Alberts, Molecular Biology (Ch.2 Cellular chemistry).
(2) Ratner, Biomaterials Science (Ch. 2.3, 2.4 Polymers & hydrogels).
(3) Walsh, Protein Biochemistry, (Ch. 2, Protein Structure).
(4) Nath et. al. Analytical chemistry, 74(3): 504-509, 2002.
(5) DeMonte, D., et. al. Proteins DOI: 10.1002/prot.24320, 2013.
(6) Feldhaus, M.J., et al. Nature Biotechnology 21 (2): 163–70, 2003.
(7) Link, A.J., et al. PNAS 103 (27): 10180–85, 2006.
(8) Chen, I. et al. PNAS 108 (28): 11399–404, 2011.
(9) Marín-Navarro, J., et. al. PloS One 10 (12). journals.plos.org: e0144289, 2015.
(10) Christensen, T. et al. Biomacromolecules 14 (5): 1514–19, 2013.
(11) Shimoboji, T., et al. PNAS. 99(26): 16592-16596, 2002.
(12) Puchner, E.M. et al. PNAS. 105(36): 13385–13390, 2008.
(13) Dietz, H., et al. PNAS 103 (5): 1244–47, 2006.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersM. Nash
Typegraded semester performance
Language of examinationEnglish
RepetitionRepetition only possible after re-enrolling for the course unit.
Additional information on mode of examinationRegistration modalities, date and venue of this performance assessment will include engagement in class discussions on weekly reading assignments, an in class presentation, and final oral exam.
Registration modalities, date and venue of this performance assessment are specified solely by the Uni Basel.

Learning materials

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Only public learning materials are listed.


No information on groups available.


There are no additional restrictions for the registration.

Offered in

Biotechnology MasterBiomelecular-OrientatedWInformation