636-0550-00L  Biomolecular Nanotechnology

SemesterHerbstsemester 2021
DozierendeM. Nash
Periodizitätjährlich wiederkehrende Veranstaltung
LehrspracheEnglisch



Lehrveranstaltungen

NummerTitelUmfangDozierende
636-0550-00 VBiomolecular Nanotechnology
Wednesdays 08.00-10.00 Campus Rosental 1095, Conference room E00.012
ATTENTION: This lecture will start on Wednesday, Sept. 29
2 Std.M. Nash
636-0550-00 UBiomolecular Nanotechnology
Thursday, 08.00-09.00 Campus Rosental 1060, Seminar room 2.14
ATTENTION: The first tutorial will take place on Thursday, Sept. 30
1 Std.M. Nash

Katalogdaten

KurzbeschreibungBiomolecular nanotechnology is a broad field that focuses on the study and science of biological materials including DNA, RNA and proteins at length scales below 10 nm. This is a broad overview of the topic with a focus on current research themes.
LernzielThe objective is to familiarise the students with a broad range of topics related to biotechnology, nanotechnology, and biophysics with a focus on current research and reading of scientific literature.
InhaltIntroduction to biomacromolecules; Measurement techniques for characterisation of biomacromolecules; Fundamentals of molecular recognition; Recombinant DNA; Protein engineering; Directed evolution; Protein folding; Polymers; Elastin-like polypeptides; Intelligent materials; Spatially localized hydrogels; Mechanical properties of proteins and macromolecules; Single-molecule force spectroscopy
LiteraturRepresentative literature:
(1) Alberts, Molecular Biology (Ch.2 Cellular chemistry).
(2) Ratner, Biomaterials Science (Ch. 2.3, 2.4 Polymers & hydrogels).
(3) Walsh, Protein Biochemistry, (Ch. 2, Protein Structure).
(4) Nath et. al. Analytical chemistry, 74(3): 504-509, 2002.
(5) DeMonte, D., et. al. Proteins DOI: 10.1002/prot.24320, 2013.
(6) Feldhaus, M.J., et al. Nature Biotechnology 21 (2): 163–70, 2003.
(7) Link, A.J., et al. PNAS 103 (27): 10180–85, 2006.
(8) Chen, I. et al. PNAS 108 (28): 11399–404, 2011.
(9) Marín-Navarro, J., et. al. PloS One 10 (12). journals.plos.org: e0144289, 2015.
(10) Christensen, T. et al. Biomacromolecules 14 (5): 1514–19, 2013.
(11) Shimoboji, T., et al. PNAS. 99(26): 16592-16596, 2002.
(12) Puchner, E.M. et al. PNAS. 105(36): 13385–13390, 2008.
(13) Dietz, H., et al. PNAS 103 (5): 1244–47, 2006.

Leistungskontrolle

Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird)
Leistungskontrolle als Semesterkurs
ECTS Kreditpunkte4 KP
PrüfendeM. Nash
Formbenotete Semesterleistung
PrüfungsspracheEnglisch
RepetitionRepetition nur nach erneuter Belegung der Lerneinheit möglich.
Zusatzinformation zum PrüfungsmodusRegistration modalities, date and venue of this performance assessment will include engagement in class discussions on weekly reading assignments, an in class presentation, and final oral exam.
Registration modalities, date and venue of this performance assessment are specified solely by the Uni Basel.

Lernmaterialien

Keine öffentlichen Lernmaterialien verfügbar.
Es werden nur die öffentlichen Lernmaterialien aufgeführt.

Gruppen

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Einschränkungen

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Angeboten in

StudiengangBereichTyp
Biotechnologie MasterBiomolekulare OrientierungWInformation