262-5100-00L Protein Biophysics (University of Zurich)
| Semester | Spring Semester 2021 |
| Lecturers | University lecturers |
| Periodicity | yearly recurring course |
| Language of instruction | English |
| Comment | No enrollment to this course at ETH Zurich. Book the corresponding module directly at UZH. UZH Module Code: BCH304 Mind the enrolment deadlines at UZH: https://www.uzh.ch/cmsssl/en/studies/application/deadlines.html |
| Abstract | The course includes a general introduction into protein structure and biophysics as well as into the usage of molecular dynamics simulations and other computational methods, protein structure and X-ray techniques, protein NMR for determining protein structure and dynamics as well as for folding studies and protein thermodynamics. |
| Objective | A 4 hour/week course on all aspects of protein biophysics. The course includes a general introduction into protein structure and biophysics as well as into the usage of molecular dynamics simulations and other computational methods, protein structure and X-ray techniques, protein NMR for determining protein structure and dynamics as well as for folding studies and protein thermodynamics. |
| Content | The lecture course consists of four parts: 1) non-covalent interactions, properties of water and hydrophobic effect, protein folding and misfolding, molecular dynamics simulations; 2) atomistic simulations of proteins 3) thermodynamics and kinetics of protein folding; 4) single molecule biophysics: single molecule fluorescence spectroscopy, fluorescence correlation spectroscopy, and applications to stochastic processes in biology. |