542-0003-00L Module III: Radiopharmacology and Clinical Radiopharmacy
| Semester | Herbstsemester 2020 |
| Dozierende | R. Schibli |
| Periodizität | 2-jährlich wiederkehrende Veranstaltung |
| Lehrveranstaltung | Findet dieses Semester nicht statt. |
| Lehrsprache | Englisch |
| Kommentar | Only for CAS in Radiopharmazeutischer Chemie, Radiopharmacy. The enrolment is done by the CAS study administration. |
| Kurzbeschreibung | Participants will understand concepts of Pharmacology, Toxicology and Fundamentals of Nuclear Medicine |
| Lernziel | • Pharmakokinetics and kinetic-modelling • Statistics and practical session • Radiotracers in biochemistry and molecular pharmacology • Selective modification of peptides and proteins to target GPCRs • Demonstration of experimental set up: Peptide and protein modification, radioactive assays in biochemistry • Visit ABX Radeberg • Nuclear medicine: basics and therapy • Immunology • Drug interventions/interactions/adverse reactions • Pharmacology basics, special aspects, clinical studies • Toxicology • Testsystems in toxicology and targeted therapeutics and cucleic acids • Nuclear medicine: clinical diagnostic applications in neurology • Nuclear medicine: visit to SPECT facility and radiopharmaceutical GMP lag (Tc, Ga, therapy) • Radiological imaging modalities- technology and applications • Nuclear medicine: clinical diagnostic applications in oncology • Radiopharmaceutical monographs in the European pharmacopoeia • Practical session, visit: cyclotron, GMP PET production and quality control, PET and PET/CT, therapy unit • Radioligand-binding-assays/autoradiography • In house tours in groups: radioligand-binding-assays, autoradiography, metabolite analytics with LC-MS, cyclotron and radiochemistry, highlights in Leipzig • Biological effects of radiation • Radiotracer transport and blood brain barrier • Radiotracers for neuroimaging |