752-0100-AAL Biochemistry
| Semester | Spring Semester 2020 |
| Lecturers | C. Frei |
| Periodicity | every semester recurring course |
| Language of instruction | English |
| Comment | Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. |
| Abstract | Basic knowledge of enzymology, in particular the structure, kinetics and chemistry of enzyme-catalysed reaction in vitro and in vivo. Biochemistry of metabolism: Those completing the course are able to describe and understand fundamental cellular metabolic processes. |
| Learning objective | In this self-study course, the students will gain solid biochemical knowledge about enzymology, membrane biochemistry, and central metabolism. |
| Content | Program Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry Structure and function of proteins Carbohydrates, structure of DNA Lipids an biological membranes Enzymes and enzyme kinetics Catalytic strategies Metabolism: Basic concepts and design. Repetition of basic thermodynamics Glycolysis The citric acid cycle Oxidative phosphorylation Fatty acid metabolism |
| Lecture notes | Horton et al. (Pearson) serves as lecture notes. |
| Literature | Horton, Moran, Scrimgeour, Perry, Rawn: Principles of Biochemistry, 4th ed. or Moran, Horton, Scrimgeour, Perry: Principles of Biochemistry, 5th ed. Pearson Education Limited, Essex |
| Prerequisites / Notice | Basic knowledge in biology and chemistry is a precondition. |