752-0100-AAL  Biochemistry

SemesterSpring Semester 2020
LecturersC. Frei
Periodicityevery semester recurring course
Language of instructionEnglish
CommentEnrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement.

Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit.


AbstractBasic knowledge of enzymology, in particular the structure, kinetics and chemistry of enzyme-catalysed reaction in vitro and in vivo. Biochemistry of metabolism: Those completing the course are able to describe and understand fundamental cellular metabolic processes.
ObjectiveIn this self-study course, the students will gain solid biochemical knowledge about enzymology, membrane biochemistry, and central metabolism.
ContentProgram

Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry
Structure and function of proteins
Carbohydrates, structure of DNA
Lipids an biological membranes
Enzymes and enzyme kinetics
Catalytic strategies
Metabolism: Basic concepts and design. Repetition of basic thermodynamics
Glycolysis
The citric acid cycle
Oxidative phosphorylation
Fatty acid metabolism
Lecture notesHorton et al. (Pearson) serves as lecture notes.
LiteratureHorton, Moran, Scrimgeour, Perry, Rawn: Principles of Biochemistry, 4th ed. or
Moran, Horton, Scrimgeour, Perry: Principles of Biochemistry, 5th ed.
Pearson Education Limited, Essex
Prerequisites / NoticeBasic knowledge in biology and chemistry is a precondition.