551-1415-00L Image-based Drug Screening in Human Blood for Personalized Medicine
| Semester | Autumn Semester 2019 |
| Lecturers | B. Snijder, further lecturers |
| Periodicity | yearly recurring course |
| Language of instruction | English |
| Comment | Number of participants limited to 5. The enrolment is done by the D-BIOL study administration. |
Courses
| Number | Title | Hours | Lecturers | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 551-1415-00 G | Image-based Drug Screening in Human Blood for Personalized Medicine Permission from lecturers required for all students.
Block course in the 1st quarter of the autumn semester. | 100s hrs |
| B. Snijder, further lecturers |
Catalogue data
| Abstract | Image based screening allows to measure in high throughput the phenotype of millions of individual cells to external perturbations. We have recently shown that image-based screening in human blood can help to find active treatments for patients with blood cancers. In this course we will take the students through the entire workflow (to the extent that biosafety regulations allow it). |
| Learning objective | Take the students through the entire workflow from experimental design, to screen, to imaging and analysis. -Learn to design an image-based screening experiment -Observe human blood sample handling -Perform immunofluorescence & automated confocal microscopy -Image analysis and result interpretation -Result presentation |
| Literature | -Relevant study: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(17)30208-9/fulltext -Editorial commentary: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(17)30213-2/fulltext |
Performance assessment
| Performance assessment information (valid until the course unit is held again) | |
Performance assessment as a semester course | |
| ECTS credits | 6 credits |
| Examiners | B. Snijder |
| Type | graded semester performance |
| Language of examination | English |
| Repetition | Repetition only possible after re-enrolling for the course unit. |
Learning materials
| No public learning materials available. | |
| Only public learning materials are listed. |
Groups
| No information on groups available. |
Restrictions
| General | Permission from lecturers required for all students |
Offered in
| Programme | Section | Type | |
|---|---|---|---|
| Biology Bachelor | Block Courses in 1st Quarter of the Semester | W |  |