529-0837-01L  Biomicrofluidic Engineering

SemesterHerbstsemester 2019
DozierendeA. de Mello
Periodizitätjährlich wiederkehrende Veranstaltung
KommentarNumber of participants limited to 25.

IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005.


529-0837-01 GBiomicrofluidic Engineering3 Std.
Mo15:45-17:30HCI H 8.1 »
Di11:45-12:30HCI J 7 »
16.09.11:45-12:30HCI J 3 »
A. de Mello


KurzbeschreibungMicrofluidics describes the behaviour, control and manipulation of fluids that are geometrically constrained within sub-microliter environments. The use of microfluidic devices offers an opportunity to control physical and chemical processes with unrivalled precision, and in turn provides a route to performing chemistry and biology in an ultra-fast and high-efficiency manner.
LernzielIn the course students will investigate the theoretical concepts behind microfluidic device operation, the methods of microfluidic device manufacture and the application of microfluidic architectures to important problems faced in modern day chemical and biological analysis. A design workshop will allow students to develop new microscale flow processes by appreciating the dominant physics at the microscale. The application of these basic ideas will primarily focus on biological problems and will include a treatment of diagnostic devices for use at the point-of-care, advanced functional material synthesis, DNA analysis, proteomics and cell-based assays. Lectures, assignments and the design workshop will acquaint students with the state-of-the-art in applied microfluidics.
InhaltSpecific topics in the course include, but not limited to:

1. Theoretical Concepts
Features of mass and thermal transport on the microscale
Key scaling laws
2. Microfluidic Device Manufacture
Conventional lithographic processing of rigid materials
Soft lithographic processing of plastics and polymers
Mass fabrication of polymeric devices
3. Unit operations and functional components
Analytical separations (electrophoresis and chromatography)
Chemical and biological synthesis
Sample pre-treatment (filtration, SPE, pre-concentration)
Molecular detection
4. Design Workshop
Design of microfluidic architectures for PCR, distillation & mixing
5. Contemporary Applications in Biological Analysis
Cellular analyses (single cells, enzymatic assays, cell sorting)
6. System integration
Applications in radiochemistry, diagnostics and high-throughput experimentation
SkriptLecture handouts, background literature, problem sheets and notes will be provided electronically.


Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird)
Leistungskontrolle als Semesterkurs
ECTS Kreditpunkte6 KP
PrüfendeA. de Mello
RepetitionDie Leistungskontrolle wird in jeder Session angeboten. Die Repetition ist ohne erneute Belegung der Lerneinheit möglich.
Prüfungsmodusschriftlich 75 Minuten
Zusatzinformation zum PrüfungsmodusThe final grade will be made up from the written examination (55%) and a compulsory group project (45%). The group project will involve the performance of experimental work and computer simulations. This activity will take place in the last two quarters of the course, and will typically be scheduled during normal class time. Project performance will be assessed through the grading of a written report and an oral presentation.
Hilfsmittel schriftlichScientific calculator may be used in the written examination
Diese Angaben können noch zu Semesterbeginn aktualisiert werden; verbindlich sind die Angaben auf dem Prüfungsplan.


Keine öffentlichen Lernmaterialien verfügbar.
Es werden nur die öffentlichen Lernmaterialien aufgeführt.


Keine Informationen zu Gruppen vorhanden.


PlätzeMaximal 25
VorrangDie Belegung der Lerneinheit ist bis 15.09.2019 nur durch die primäre Zielgruppe möglich
Primäre ZielgruppeChemie- und Bioingenieurwissenschaften MSc (506000)
WartelisteBis 23.09.2019

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