529-0837-01L Biomicrofluidic Engineering
Semester | Herbstsemester 2019 |
Dozierende | A. de Mello |
Periodizität | jährlich wiederkehrende Veranstaltung |
Lehrsprache | Englisch |
Kommentar | Number of participants limited to 25. IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005. |
Lehrveranstaltungen
Nummer | Titel | Umfang | Dozierende | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
529-0837-01 G | Biomicrofluidic Engineering | 3 Std. |
| A. de Mello |
Katalogdaten
Kurzbeschreibung | Microfluidics describes the behaviour, control and manipulation of fluids that are geometrically constrained within sub-microliter environments. The use of microfluidic devices offers an opportunity to control physical and chemical processes with unrivalled precision, and in turn provides a route to performing chemistry and biology in an ultra-fast and high-efficiency manner. |
Lernziel | In the course students will investigate the theoretical concepts behind microfluidic device operation, the methods of microfluidic device manufacture and the application of microfluidic architectures to important problems faced in modern day chemical and biological analysis. A design workshop will allow students to develop new microscale flow processes by appreciating the dominant physics at the microscale. The application of these basic ideas will primarily focus on biological problems and will include a treatment of diagnostic devices for use at the point-of-care, advanced functional material synthesis, DNA analysis, proteomics and cell-based assays. Lectures, assignments and the design workshop will acquaint students with the state-of-the-art in applied microfluidics. |
Inhalt | Specific topics in the course include, but not limited to: 1. Theoretical Concepts Features of mass and thermal transport on the microscale Key scaling laws 2. Microfluidic Device Manufacture Conventional lithographic processing of rigid materials Soft lithographic processing of plastics and polymers Mass fabrication of polymeric devices 3. Unit operations and functional components Analytical separations (electrophoresis and chromatography) Chemical and biological synthesis Sample pre-treatment (filtration, SPE, pre-concentration) Molecular detection 4. Design Workshop Design of microfluidic architectures for PCR, distillation & mixing 5. Contemporary Applications in Biological Analysis Microarrays Cellular analyses (single cells, enzymatic assays, cell sorting) Proteomics 6. System integration Applications in radiochemistry, diagnostics and high-throughput experimentation |
Skript | Lecture handouts, background literature, problem sheets and notes will be provided electronically. |
Leistungskontrolle
Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird) | |
Leistungskontrolle als Semesterkurs | |
ECTS Kreditpunkte | 6 KP |
Prüfende | A. de Mello |
Form | Sessionsprüfung |
Prüfungssprache | Englisch |
Repetition | Die Leistungskontrolle wird in jeder Session angeboten. Die Repetition ist ohne erneute Belegung der Lerneinheit möglich. |
Prüfungsmodus | schriftlich 75 Minuten |
Zusatzinformation zum Prüfungsmodus | The final grade will be made up from the written examination (55%) and a compulsory group project (45%). The group project will involve the performance of experimental work and computer simulations. This activity will take place in the last two quarters of the course, and will typically be scheduled during normal class time. Project performance will be assessed through the grading of a written report and an oral presentation. |
Hilfsmittel schriftlich | Scientific calculator may be used in the written examination |
Diese Angaben können noch zu Semesterbeginn aktualisiert werden; verbindlich sind die Angaben auf dem Prüfungsplan. |
Lernmaterialien
Keine öffentlichen Lernmaterialien verfügbar. | |
Es werden nur die öffentlichen Lernmaterialien aufgeführt. |
Gruppen
Keine Informationen zu Gruppen vorhanden. |
Einschränkungen
Plätze | Maximal 25 |
Vorrang | Die Belegung der Lerneinheit ist bis 15.09.2019 nur durch die primäre Zielgruppe möglich |
Primäre Zielgruppe | Chemie- und Bioingenieurwissenschaften MSc (506000) |
Warteliste | Bis 23.09.2019 |