Chemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions.
Objective
Acquisition of a basic repertoire of synthetic methods including important reactions of aldehydes, ketones, carboxylic acids and carboxylic acid derivatives, as well as eliminations and fragmentations. Particular emphasis is placed on the understanding of reaction mechanisms and the correlation between structure and reactivity. A deeper understanding of the concepts presented during the lecture is reached by solving the problems handed out each time and discussed one week later in the exercise class.
Content
Chemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions.
Lecture notes
A pdf file of the printed lecture notes is provided online. Supplementary material may be provided online.
Literature
No set textbooks. Optional literature will be proposed at the beginning of the class and in the lecture notes.
Performance assessment
Performance assessment information (valid until the course unit is held again)
Performance assessment as a two-semester course together with 529-0222-00L Organic Chemistry II
(next semester)
For programme regulations
(Examination block)
Bachelor's Degree Programme in Chemical Engineering 2006; Version 27.03.2018 (Examination Block I) Bachelor's Degree Programme in Chemical Engineering 2018; Version 26.09.2022 (Examination Block I) Bachelor's Degree Programme in Chemistry 2005; Version 27.03.2018 (Examination Block I) Bachelor's Degree Programme in Chemistry 2018; Version 26.09.2022 (Examination Block I) Bachelor's Degree Programme in Interdisciplinary Sciences 2010; Version 27.03.2018 (Examination Block) Bachelor's Degree Programme in Interdisciplinary Sciences 2018; Version 12.07.2022 (Examination Block)
ECTS credits
6 credits
Performance assessment as a semester course
(other programmes)
The performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examination
written 60 minutes
Written aids
keine
If the course unit is part of an examination block, the credits are allocated for the successful completion of the whole block. This information can be updated until the beginning of the semester; information on the examination timetable is binding.