551-1402-00L  Molecular and Structural Biology VI: Biophysical Analysis of Macromolecular Mechanisms

SemesterSpring Semester 2019
LecturersR. Glockshuber, T. Ishikawa, S. Jonas, B. Schuler, D. Veprintsev, E. Weber-Ban
Periodicityyearly recurring course
Language of instructionEnglish
CommentThis course is strongly recommended for the Masters Major "Biology and Biophysics".



Courses

NumberTitleHoursLecturers
551-1402-00 VMolecular and Structural Biology VI: Biophysical Analysis of Macromolecular Mechanisms2 hrs
Wed08:45-10:30HIT H 42 »
R. Glockshuber, T. Ishikawa, S. Jonas, B. Schuler, D. Veprintsev, E. Weber-Ban

Catalogue data

AbstractThe course is focussed on biophysical methods for characterising conformational transitions and reaction mechanisms of proteins and biological mecromolecules, with focus on methods that have not been covered in the Biology Bachelor Curriculum.
ObjectiveThe goal of the course is to give the students a broad overview on biopyhsical techniques available for studying conformational transitions and complex reaction mechanisms of biological macromolecules. The course is particularly suited for students enrolled in the Majors "Structural Biology and Biophysics", "Biochemistry" and "Chemical Biology" of the Biology MSc curriculum, as well as for MSc students of Chemistry and Interdisciplinary Natural Sciences".
ContentThe biophysical methods covered in the course include advanced reaction kinetics, methods for the thermodynamic and kinetic analysis of protein-ligand interactions, static and dynamic light scattering, analytical ultracentrifugation, spectroscopic techniques such as fluorescence anisotropy, fluorescence resonance energy transfer (FRET) and single molecule fluorescence spectrosopy, modern electron microscopy techniques, atomic force microscopy, and isothermal and differential scanning calorimetry.
Lecture notesCourse material from the individual lecturers wil be made available at the sharepoint website

Link
Prerequisites / NoticeFinished BSc curriculum in Biology, Chemistry or Interdisciplinary Natural Sciences. The course is also adequate for doctoral students with research projects in structural biology, biophysics, biochemistry and chemical biology.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersR. Glockshuber, T. Ishikawa, S. Jonas, B. Schuler, D. Veprintsev, E. Weber-Ban
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationwritten 60 minutes
Written aidsNicht programmierbare Taschenrechner
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

Learning materials

No public learning materials available.
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
Biology MasterElective Compulsory Master CoursesWInformation
Biology MasterElective Compulsory Master CoursesWInformation
Biology MasterElective Compulsory Master CoursesWInformation
MAS in Medical PhysicsCore CoursesWInformation