529-0233-01L Organic Synthesis: Methods and Strategies
|Semester||Autumn Semester 2018|
|Lecturers||E. M. Carreira|
|Periodicity||yearly recurring course|
|Language of instruction||English|
|Abstract||The complex relation between structural analysis, methods leading to desired transformations, and insight into reaction mechanisms is exemplified. Relations between retrosynthetic analysis of target structures, synthetic methods and their combination in a synthetic strategy.|
|Objective||Extension and deepening of the knowledge in organic synthesis.|
|Content||Concepts of the planning of organic synthesis (strategy and tactics), retrosynthetic analysis. Structure-reactivity relation in the context of the synthesis of complex molecules.|
|Literature||K. C. Nicolaou, E. J. Sorensen, Classics in Total Synthesis, Wiley-VCH 1996.|
K. C. Nicolaou, S. A. Snyder, Classics in Total Synthesis II, Wiley-VCH 2003.
K. C. Nicolaou, J. Chen, Classics in Total Synthesis III, Wiley-VCH 2011.
|Prerequisites / Notice||OC I-IV|