529-0233-00L  Organic Synthesis: Methods and Strategies

SemesterAutumn Semester 2018
LecturersE. M. Carreira
Periodicityyearly recurring course
Language of instructionEnglish
CommentOnly for Chemistry MSc, Programme Regulations 2005.


AbstractThe complex relation between structural analysis, methods leading to desired transformations, and insight into reaction mechanisms is exemplified. Relations between retrosynthetic analysis of target structures, synthetic methods and their combination in a synthetic strategy.
ObjectiveExtension and deepening of the knowledge in organic synthesis.
ContentConcepts of the planning of organic synthesis (strategy and tactics), retrosynthetic analysis. Structure-reactivity relation in the context of the synthesis of complex molecules.
LiteratureK. C. Nicolaou, E. J. Sorensen, Classics in Total Synthesis, Wiley-VCH 1996.
K. C. Nicolaou, S. A. Snyder, Classics in Total Synthesis II, Wiley-VCH 2003.
K. C. Nicolaou, J. Chen, Classics in Total Synthesis III, Wiley-VCH 2011.
Prerequisites / NoticeOC I-IV