551-0334-00L Molecular Defense Mechanisms of Fungi
| Semester | Spring Semester 2018 |
| Lecturers | M. Künzler |
| Periodicity | yearly recurring course |
| Language of instruction | English |
| Comment | Number of participants limited to 6. The enrolment is done by the D-BIOL study administration. |
| Abstract | The course offers an introduction into the molecular biology of fungi by participation in a current research project on Molecular Defense Mechanisms of Fungi. The performed experiments, in conjunction with accompanying seminars should enable the students to answer questions regarding central aspects of innate defense mechanisms and the life style of multicellular fungi. |
| Learning objective | The course should enable the students to answer questions regarding central aspects of innate defense mechanisms and the life style of multicellular fungi, and their experimental accessibility. |
| Content | Experiments include the isolation, identification and characterization of defense effector molecules from multicellular fungi. Methods include molecular genetics, biochemistry, mass spectrometry and biotoxicity assays towards different model organisms including fungi, bacteria, insects and nematodes. Experiments are supported by seminars giving an overview over Fungal Defense Mechanisms and Fungal Lifestyle. |
| Literature | http://www.micro.biol.ethz.ch/research/aebi/kuenzler/publications |
| Prerequisites / Notice | The "Leistungskontrolle" is composed of: -Oral presentation of results -Short oral exam (20') at the end of the course -Written report -Performance in the laboratory |