551-0362-00L Analysis of Signaling Networks by Mass Spectrometry
| Semester | Frühjahrssemester 2018 |
| Dozierende | M. Gstaiger, M. Claassen, B. Wollscheid |
| Periodizität | jährlich wiederkehrende Veranstaltung |
| Lehrsprache | Englisch |
| Kommentar | Number of participants limited to 10. The enrolment is done by the D-BIOL study administration. |
| Kurzbeschreibung | This course provides the theoretical and practical basis for the biochemical and computational analysis of signaling networks using quantitative mass spectrometry and advanced statistical methods. |
| Lernziel | In this course we will introduce basic and emerging techniques to study dynamic signalling networks using state of the art quantitative mass spectrometry techniques. This will involve the systematic characterization of signaling networks by affinity purification and phospho-peptide enrichment combined with quantitative mass spectrometry. We will also introduce and apply computational tools for statistical analysis, data visualization and network inference to build new hypothesis on the basis of the obtained data. |
| Voraussetzungen / Besonderes | Der Kurs setzt Grundkenntnisse der Analyse von Proteinen mithilfe der Massenspektrometrie voraus. Von Vorteil sind auch Grundkenntnisse in R oder MatLab. Wir empfehlen daher dringend zur Vorbereitung den Blockkurs 551-0352-00L "Protein Analysis by Mass Spectrometry" zu besuchen. |