535-0423-00L  Drug Delivery and Drug Targeting

SemesterAutumn Semester 2017
LecturersJ.‑C. Leroux, A. Spyrogianni Roveri
Periodicityyearly recurring course
Language of instructionEnglish



Courses

NumberTitleHoursLecturers
535-0423-00 VDrug Delivery and Drug Targeting1.5 hrs
Tue/112:45-15:30HIL E 9 »
J.‑C. Leroux, A. Spyrogianni Roveri

Catalogue data

AbstractThe students gain an overview on current principles, methodologies and systems for controlled delivery and targeting of drugs. This enables the students to understand and evaluate the field in terms of scientific criteria.
Learning objectiveThe students dispose of an overview on current principles and systems for the controlled delivery and targeting of drugs. The focus of the course lies on developing a capacity to understand the involved technologies and methods, as well as an appreciation of the chances and constraints of their therapeutic usage, with prime attention on anticancer drugs, therapeutic peptides, proteins, nucleic acids and vaccines.
ContentThe course covers the following topics: drug targeting and delivery principles, macromolecular drug carriers, liposomes, micelles, micro/nanoparticles, gels and implants, administration of vaccines, targeting at the gastrointestinal level, synthetic carriers for nucleic acid drugs, ophthalmic devices and novel trends in transdermal and nasal drug delivery.
Lecture notesSelected lecture notes, documents and supporting material will be directly provided or may be downloaded using

http://www.galenik.ethz.ch/teaching/drug_del_drug_targ

The website also displays additional information on peroral delivery systems, transdermal systems and systems for alternative routes (nasal, pulmonary) of delivery. These fields are covered in detail in the course Galenische Pharmazie II (Galenical Pharmacy II).
LiteratureA.M. Hillery, K. Park. Drug Delivery: Fundamentals & Applications, second edition, CRC Press, Boca Raton, FL, 2017.

B. Wang B, L. Hu, T.J. Siahaan. Drug Delivery - Principles and Applications, second edition, John Wiley & Sons, Hoboken NJ, 2016.

Y. Perrie, T. Rhades. Pharmaceutics - Drug Delivery and Targeting, second edition, Pharmaceutical Press, London and Chicago, 2012.

Further references will be provided in the course.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits2 credits
ExaminersJ.-C. Leroux, A. Spyrogianni Roveri
Typegraded semester performance
Language of examinationEnglish
RepetitionRepetition possible without re-enrolling for the course unit.
Additional information on mode of examinationShort oral communication about a recent publication in the field of drug delivery and targeting (40%). Oral examination on one or more randomly selected topics of the course (ca. 20 min) (60%).

Learning materials

No public learning materials available.
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
Biomedical Engineering MasterRecommended Elective CoursesWInformation
Biotechnology MasterElectivesWInformation
Health Sciences and Technology MasterElective Courses IIWInformation
MAS in Medical PhysicsElectivesWInformation
MAS in Medical PhysicsElectivesWInformation
Pharmaceutical Sciences MasterElectives IWInformation
Pharmaceutical Sciences BachelorCompensatory CoursesWInformation
Pharmacy MasterElectivesWInformation