535-0239-00L Practical Course in Medicinal Chemistry
| Semester | Autumn Semester 2021 |
| Lecturers | J. Hall, M. Detmar, C. Halin Winter, J. Scheuermann |
| Periodicity | yearly recurring course |
| Language of instruction | English |
| Abstract | The course comprises experiments relating to concepts of medicinal chemistry including statistical processing, fitting of experimental data, computer modeling of protein structures, experimental measurement of affinity constants and kinetic dissociation constants for protein ligands. The chemical stability of a drug will be studied. Basic gene cloning and protein expression will be introduced. |
| Learning objective | Knowledge of experimental methods in drug discovery and development |
| Content | Characterisation of the biophysical and biological properties of drugs. |
| Lecture notes | Scripts |
| Literature | Original literature |
| Prerequisites / Notice | Requirements: Laboratory course in Pharmaceutical Anaytics; Lecture Medicinal Chemistry I in the same semester or earlier. Safety conceptt: https://chab.ethz.ch/studium/bachelor1.html |