551-0307-01L  Molecular and Structural Biology II: Molecular Machines and Cellular Assemblies

SemesterSpring Semester 2020
LecturersN. Ban, F. Allain, S. Jonas, M. Pilhofer
Periodicityyearly recurring course
Language of instructionEnglish
CommentD-BIOL students are obliged to take part I and part II as a two-semester course.


AbstractThis course on advanced topics in Molecular Biology and Biochemistry will cover the structure and function of cellular assemblies. General topics in basic biochemistry will be further developed with examples of the function of large cellular machines involved in DNA packaging, translation, virus architecture, RNA processing, cell-cell interactions, and the molecular basis of CRISPER systems.
ObjectiveStudents will gain a deep understanding of large cellular assemblies and the structure-function relationships governing their function in fundamental cellular processes. The lectures throughout the course will be complemented by exercises and discussions of original research examples to provide students with a deeper understanding of the subjects and to encourage active student participation.
ContentAdvanced class covering the state of the research in structural molecular biology of basic cellular processes with emphasis on the function of large cellular assemblies.
Lecture notesUpdated handouts will be provided during the class.
LiteratureThe lecture will be based on the latest literature. Additional suggested
literature:
Branden, C., and J. Tooze, Introduction to Protein Structure, 2nd ed.
(1995). Garland, New York.