551-0324-00L  Systems Biology

SemesterSpring Semester 2018
LecturersR. Aebersold, B. Christen, M. Claassen, U. Sauer
Periodicityyearly recurring course
Language of instructionEnglish



Courses

NumberTitleHoursLecturers
551-0324-00 VSystems Biology4 hrs
Mon12:45-14:30HCI J 6 »
Tue07:45-09:30HCI J 6 »
R. Aebersold, B. Christen, M. Claassen, U. Sauer

Catalogue data

AbstractIntroduction to experimental and computational methods of systems biology. By using baker’s yeast as a thread through the series, we focus on global methods for analysis of and interference with biological functions. Illustrative applications to other organisms will highlight medical and biotechnological aspects.
Objective- obtain an overview of global analytical methods
- obtain an overview of computational methods in systems biology
- understand the concepts of systems biology
ContentOverview of global analytical methods (e.g. DNA arrays, proteomics, metabolomics, fluxes etc), global interference methods (siRNA, mutant libraries, synthetic lethality etc.) and imaging methods. Introduction to mass spectrometry and proteomics. Concepts of metabolism in microbes and higher cells. Systems biology of developmental processes. Concepts of mathematical modeling and applications of computational systems biology.
Lecture notesno script
LiteratureThe course is not taught by a particular book, but some books are suggested for further reading:

- Systems biology in Practice by Klipp, Herwig, Kowald, Wierling und Lehrach. Wiley-VCH 2005

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits6 credits
ExaminersU. Sauer, R. Aebersold, B. Christen, M. Claassen
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationwritten 150 minutes
Written aidsKeine Hilfsmittel zugelassen.
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

Learning materials

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Only public learning materials are listed.

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