G.V. Shivashankar: Catalogue data in Autumn Semester 2023 |
| Name | Prof. Dr. G.V. Shivashankar |
| Field | Mechano-Genomics |
| Address | Paul Scherrer Institute Forschungsstrasse 111 OFLC 107 5232 Villigen PSI SWITZERLAND |
| g.v.shivashankar@hest.ethz.ch | |
| Department | Health Sciences and Technology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 376-0303-00L | Colloquium in Translational Science (Autumn Semester) Does not take place this semester. | 1 credit | 1K | A. Alimonti, V. Falk, J. Goldhahn, K. Maniura, R. M. Rossi, S. Schürle-Finke, G. Shivashankar, E. Vayena, V. Vogel | |
| Abstract | Current topics in translational medicine presented by speakers from academia and industry. | ||||
| Learning objective | Getting insight into actual areas and problems of translational medicine. | ||||
| Content | Timely and concise presentations of postgraduate students, post-docs, senior scientists, professors, as well as external guests from both academics and industry will present topics of their interest related to translational medicine. | ||||
| Prerequisites / Notice | No compulsory prerequisites, but student should have basic knowledge about biomedical research. | ||||
| 376-1348-00L | Cellular Ageing | 3 credits | 2V | G. Shivashankar | |
| Abstract | Cells undergo major functional alterations as we age. In this course, we will discuss the basic molecular and cell biological mechanisms of cellular ageing. We will also discuss diseases related to cellular ageing and current rejuvenation and therapeutic strategies for cellular ageing in health and disease. | ||||
| Learning objective | - Basic molecular and cell biological mechanisms of cellular ageing; - Diseases related to cellular ageing; - current rejuvenation and therapeutic strategies for cellular ageing in health and disease. | ||||
| Content | Lecture-1: Hallmarks of cellular ageing Lecture-2: Cellular microenvironment & extra-cellular matrix Lecture-3: Cell morphometric changes & cytoskeletal remodeling Lecture-4: Proteostasis Lecture-5: Mitochondrial dysfunction Lecture-6: Endo-membrane signaling Lecture-7: Nuclear signaling & epigenetic alternations Lecture-8: Chromatin remodeling & gene expression Lecture-9: Genomic integrity Lecture-10: Ageing cell secretome and cellular homeostasis Lecture-11: Diseases associated with cellular ageing Lecture-12: Cellular rejuvenation strategies Lecture-13: Therapeutic interventions to cellular ageing Lecture-14: Concluding lecture | ||||