Isabelle Mansuy: Catalogue data in Spring Semester 2012

Name Prof. Dr. Isabelle Mansuy
FieldNeuroepigenetics
Address
Institut für Neurowissenschaften
ETH Zürich, Y55 H 66
Winterthurerstrasse 190
8057 Zürich
SWITZERLAND
Telephone+41 44 635 33 60
Fax+41 44 635 33 03
E-mailimansuy@ethz.ch
DepartmentHealth Sciences and Technology
RelationshipFull Professor

NumberTitleECTSHoursLecturers
376-1346-00LMolecular Mechanisms of Learning and Memory Restricted registration - show details 6 credits7GI. Mansuy
AbstractThis course will provide an overview of molecular techniques used to investigate the mechanisms of learning and memory in the mouse. It will focus on state-of-the-art methods to manipulate gene expression in the adult brain, and analyse the effect in vitro using biochemical, molecular, electrophysiological and proteomic tools, and in vivo by behavioral testing.
ObjectiveThe goal of this practical is to give students an overview of molecular techniques used to investigate the mechanisms of learning and memory in the mouse. It will focus on state-of-the-art methods to genetically manipulate gene expression in the adult brain, and analyse the effect in vitro using biochemical, molecular, electrophysiological and proteomic tools, and in vivo by behavioral testing.
Content5-6 individual projects covering various aspects of the analysis of mouse models with impaired or improved learning and memory will be offered i.e. the analysis of transgene expression in various brain areas and cellular compartments, DNA chips in transgenic mice, phosphoproteomic analysis in neuronal subcompartments, examination of fear-associated memory in mutant mice.
Lecture notesProvided at the beginning of the practical.
376-1414-00LCurrent Topics in Brain Research1 credit1.5KM. E. Schwab, F. Helmchen, I. Mansuy, O. L. D. Raineteau
AbstractDifferent national and international scientific guests are invited to present and discuss their actual scientific results.
ObjectiveTo exchange scientific knowledge and data and to promote communication and collaborations among researchers.
ContentDifferent scientific guests working in the field of molecular cognition, neurochemistry, neuromorphology and neurophysiology present their latest scientific results.
Lecture notesno handout
Literatureno literature
376-1416-00LNeuroscience Information 2 credits2VK. A. Martin, I. Mansuy, M. E. Schwab, B. Tews
AbstractDevelopment and function of the nervous system incl. higher brain functions such as cognition and learning. Introduction into basic concepts and methods in the neurosciences.
ObjectiveUnderstanding of the developing and adult vertebrate nervous system, of the senses, the machinery and functional mechanisms of learning and cognition, and the basic concepts and methods in neurobiology.
ContentThe lectures of Prof. Schwab provide an introduction to the development of the nervous system and the maintenance, plasticity and repair of the nervous system (trophic factors, receptor-tyr-kinases, stem cells); Dr. Tews will talk about neurotransmission, neuropharmacology and glial cells. Prof. Martin’s part will introduce the different sensory systems. The lectures of Prof. Mansuy will introduce higher brain functions such as learning, memory and cognition and will present recent theories and finding of those fields.
Lecture notesThe course will include textbook readings, lecture handouts, and articles from the literature.
Available handouts can be downloaded at https://team.biol.ethz.ch/e-learn/551-0416-00L (Logon: <username>@d.ethz.ch oder d\<username> und ETH Email Password).
LiteratureCampbell, Reece: Biologie (8. Auflage) Pearson Studium

Purves et al.: Neuroscience, 3rd or 4th edition, Sinauer Associates