Sabine Werner: Catalogue data in Spring Semester 2022 |  |
| Name | Prof. Dr. Sabine Werner |
| Field | Zellbiologie |
| Address | Inst. f. Molecular Health Sciences ETH Zürich, HPL F 12 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 39 41 |
| Fax | +41 44 633 11 74 |
| sabine.werner@biol.ethz.ch | |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 551-0326-00L | Cell Biology  | 6 credits | 4V | S. Werner, N. Aceto, H. Gehart, W. Kovacs, M. Schäfer, U. Suter, A. Wutz | ||||||||
| Abstract | This Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism. | |||||||||||
| Learning objective | -To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project. -To convey knowledge about neuron-glia interactions in health and disease. - To provide information on different types of stem cells and their function in health and disease -To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases -To convey knowledge on the mechanisms underlying repair of injured tissues -To provide the students with an overview of mitochondrial dynamics. -Providing an understanding of RNA processing reactions and their regulations. -To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses. -To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level. -Providing the background and context that foster cross-disciplinary scientific thinking. | |||||||||||
| 551-1518-00L | Molecular Mechanisms of Health and Disease | 2 credits | 2G | S. Werner, N. Aceto, M. Kopf, A. Oxenius | ||||||||
| Abstract | The course builds on the Fundamentals in Biology courses that are taught during the first three semesters. Students will be introduced into molecular disease mechanisms with a focus on the immune system and its role in health and disease and on cancer biology. | |||||||||||
| Learning objective | To understand the fundamental developments and functions of immune defense in multicellular organisms. To understand the principles of physical barriers, mechanisms of local and systemic defense pathways, migration and communication of and in between immune cells, the fundamental principles of self versus non-self recognition To understand the molecular and functional differences between a normal cell and a cancer cell To understand the molecular mechanisms underlying cancer development and progression to metastasis, including the role of immune cells, environmental toxins and cancer-promoting viruses To understand how vulnerabilities of cancer cells are exploited for modern cancer therapy | |||||||||||
| Lecture notes | Powerpoint Slides of the Course | |||||||||||
| Literature | Cancer chapter of "Alberts, Molecular Biology of the Cell, 6th edition" | |||||||||||
| Competencies |
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