| Number | Title | ECTS | Hours | Lecturers |
|---|
| 535-0423-00L | Drug Delivery and Drug Targeting  | 2 credits | 1.5V | J.‑C. Leroux,
A. Steinauer |
| Abstract | The students gain an overview on current principles, methodologies and systems for controlled delivery and targeting of drugs. This enables the students to understand and evaluate the field in terms of scientific criteria. |
| Learning objective | The students dispose of an overview on current principles and systems for the controlled delivery and targeting of drugs. The focus of the course lies on developing a capacity to understand the involved technologies and methods, as well as an appreciation of the chances and constraints of their therapeutic usage, with prime attention on anticancer drugs, therapeutic peptides, proteins, nucleic acids and vaccines. |
| Content | The course covers the following topics: drug targeting and delivery principles, macromolecular drug carriers, liposomes, micelles, micro/nanoparticles, gels and implants, administration of vaccines, targeting at the gastrointestinal level, synthetic carriers for nucleic acid drugs, ophthalmic devices, novel trends in transdermal and nasal drug delivery and 3D printing of drug delivery systems. |
| Lecture notes | Selected lecture notes, documents and supporting material will be directly provided or may be downloaded from the course website. |
| Literature | A.M. Hillery, K. Park. Drug Delivery: Fundamentals & Applications, second edition, CRC Press, Boca Raton, FL, 2017.
B. Wang B, L. Hu, T.J. Siahaan. Drug Delivery - Principles and Applications, second edition, John Wiley & Sons, Hoboken NJ, 2016.
Y. Perrie, T. Rhades. Pharmaceutics - Drug Delivery and Targeting, second edition, Pharmaceutical Press, London and Chicago, 2012.
Further references will be provided in the course. |
Competencies | | Subject-specific Competencies | Concepts and Theories | assessed | | Techniques and Technologies | assessed | | Method-specific Competencies | Analytical Competencies | assessed | | Decision-making | assessed | | Media and Digital Technologies | fostered | | Problem-solving | assessed | | Project Management | fostered | | Social Competencies | Communication | assessed | | Cooperation and Teamwork | assessed | | Customer Orientation | fostered | | Leadership and Responsibility | fostered | | Self-presentation and Social Influence | fostered | | Sensitivity to Diversity | fostered | | Negotiation | fostered | | Personal Competencies | Adaptability and Flexibility | assessed | | Creative Thinking | fostered | | Critical Thinking | assessed | | Integrity and Work Ethics | fostered | | Self-awareness and Self-reflection | fostered | | Self-direction and Self-management | fostered |
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