Naresh Kumar: Catalogue data in Spring Semester 2022

Name Dr. Naresh Kumar
Address
Professur f. Analytische Chemie
ETH Zürich, HCI E 331
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
SWITZERLAND
Telephone+41 44 633 48 38
E-mailnaresh.kumar@org.chem.ethz.ch
DepartmentChemistry and Applied Biosciences
RelationshipLecturer

NumberTitleECTSHoursLecturers
529-0059-00LNanoscale Molecular Imaging3 credits2GN. Kumar, R. Zenobi
AbstractThis course will provide comprehensive knowledge about the principal analytical techniques for nanoscale molecular imaging as well their practical applications. In addition to the fundamental concepts, the students will also learn to apply the advanced molecular characterization tools to solve problems in the chemical, biological and material sciences.
ObjectiveThis course will provide comprehensive knowledge about the principal analytical techniques for nanoscale molecular imaging as well their practical applications. In addition to the fundamental concepts, the students will also learn to apply the advanced molecular characterization tools to solve problems in the chemical, biological and material sciences.
ContentNanoscale molecular imaging using fluorescence spectroscopy
-Structured Illumination Microscopy (SIM)
-Stimulated Emission Depletion Microscopy (STED)
-Direct stochastic optical reconstruction microscopy (dSTORM)
-Photoactivated localization microscopy (PALM)

Nanoscale molecular imaging using Raman spectroscopy
-Scanning near-field optical microscopy (aperture SNOM)
-Tip-enhanced Raman spectroscopy (TERS): Based on both atomic force microscopy (AFM) & scanning tunnelling microscopy (STM)

Nanoscale molecular imaging using infra-red (IR) spectroscopy
-Nanoscale Fourier-transform Infrared Spectroscopy (Nano-FTIR)
-Tapping AFM-IR
-Photothermal AFM-IR

Nanoscale molecular imaging using ions
-Nanoscale secondary ion mass spectrometry (NanoSIMS)

Single molecule imaging techniques
-Scanning probe microscopy: STM & AFM
-Ultrahigh vacuum (UHV)-TERS
-Cryogenic electron microscopy (Cryo-EM)
Lecture notesLecture notes will be made available online.
LiteratureInformation about relevant literature will be available in the lecture & in the lecture notes.
Prerequisites / NoticeExercises will be an integral part of the lecture.
529-0289-00LSpectra Interpretation of Organic Compounds2 credits2GR. Zenobi, K. Eyer, N. Kumar, Y. Yamakoshi
AbstractExercises in interpretation of molecular spectra
ObjectiveMastering the interpretation of molecular spectra.
ContentIn the first part of the lecture, the students work in small groups on solving particular problems in structure elucidation, interpreting mass, 1H-NMR, 13C-NMR, IR, and UV/VIS spectra, optionally in discussion with the lecturers. In the second part the problems are solved by a lecturer.
Lecture notesSpectroscopic problems will be distributed
LiteratureE. Pretsch, P. Bühlmann, M. Badertscher, Structure Determination of Organic Compounds: Tables of Spectral Data, Springer-Verlag, Berlin, 2009, 4th revised and enlarged Engl. ed.

E. Pretsch, G. Tóth, M. E. Munk, M. Badertscher, Computer-Aided Structure Elucidation: Spectra Interpretation and Structure Generation, Wiley-VCH, Weinheim, 2002.
Prerequisites / NoticeThe course is based on the lectures Analytical Chemistry I (529-0051-00) and Analytical Chemistry II (529-0058-00).
Solutions to the problems will be posted on the internet.