Kathrin Lang: Catalogue data in Spring Semester 2023 |
Name | Prof. Dr. Kathrin Lang |
Field | Chemical Biology |
Address | Professur für Chemische Biologie ETH Zürich, HCI F 337 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
Telephone | +41 44 633 43 84 |
kathrin.lang@org.chem.ethz.ch | |
URL | https://lang.ethz.ch/ |
Department | Chemistry and Applied Biosciences |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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529-0074-00L | BCB IV: Analytical Biochemistry and Biophysics | 5 credits | 7P | K. Lang, J. W. Bode, M. Fottner, C. H. Giese, E. C. Meister, T. Segawa | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Practical Introduction to Experimental Methods in Analytical and Bioanalytical Chemistry | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | To acquire a sound knowledge of the instrumentation and methods for the analysis of molecules, including organic compounds and biological molecules. To learnabout the most important practical techniques in analytical chemistry. To write critical reports for each experiment and analytical technique. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | The course will comprise of maximum 10 experiments from the following themes: Spectroscopic structural characterisation, analytical characterisation, Bio-physical characterisation. Experiments that will be part of this curriculum are: Circular dichroism (CD) spectroscopy, UV spectroscopy, Mass Spectromety, Nuclear Magnetic Resonance, HPLC and Size exclusion separations, Isothermal titration calorimetry as well as a number of other bio-physical and biological characterisation techniques. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Learning Materials will be made available on an online platform (web page or Moodle) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | Learning Materials will be made available on an online platform (web page or Moodle) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | Prerequisites / Notice This practical course is only for students enrolled in BCB. Additionally the following courses have to be successfully completed: 529-0016-00 P BCBIII Organic Chemistry (Praktikum) 529-0011-04 "Allgemeine Chemie (Praktikum)" 529-0051-00 "Analytische Chemie" I (3. Semester) 551-0128-00L Fundamentals of Biology I Furthermore, enrolment in parallel to the lab class, or completed in an earlier semester is requested for the following course: 529-0058-00 "Analytische Chemie II" (4. Semester) BCB Students should also be enrolled in "Instumentalanalyse organischer Verbindungen". | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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529-0299-00L | Organic Chemistry | 0 credits | 1.5K | J. W. Bode, E. M. Carreira, P. Chen, K. Lang, B. Morandi, H. Wennemers, R. Zenobi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Updates on Research and Contemporary Literature in Organic Chemistry and Chemical Biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Problem solving in organic chemistry and chemical biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
529-0732-00L | Proteins and Lipids Note for BSc Biology students: Only one of the two concept courses 529-0731-00 Nucleic Acids and Carbohydrates (autumn semester) or 529-0732-00 Proteins and Lipids (spring semester) can be counted for the Bachelor's degree. | 6 credits | 3G | K. Lang | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | An overview of the relationship between protein sequence, conformation and function. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Overview of the relationship between protein sequence, conformation and function. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Proteins, structures and properties, (bio)synthesis of polypeptides, protein folding and design, protein engineering, chemical modification of proteins, proteomics. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | General Literature: - T.E. Creighton: Proteins: Structures and Molecular Properties, 2nd Edition, H.W. Freeman and Company, New York, 1993. - C. Branden, J. Tooze , Introduction to Protein Structure, Garland Publishing, New York, 1991. - J. M. Berg, J. L. Tymoczko, L. Stryer: Biochemistry, 5th edition, H.W. Freeman and Company, New York, 2002. - G.A. Petsko, D. Ringe: Protein Structure and Function, New Science Press Ltd., London, 2004. Original Literature: Citations from the original literature relevant to the individual lectures will be assigned weekly. |