Helmuth Gehart: Catalogue data in Spring Semester 2022 |  |
| Name | Prof. Dr. Helmuth Gehart |
| Field | Tumour and Stem Cell Dynamics |
| Address | Tumor- und Stammzelldynamik ETH Zürich, HPL J 16.2 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 06 20 |
| helmuth.gehart@biol.ethz.ch | |
| Department | Biology |
| Relationship | Assistant Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 551-0130-00L | Fundamentals of Biology II   Registrations via myStudies until 2.2.2022 at the latest. Subsequent registrations will not be considered. | 8 credits | 8P | M. Gstaiger, N. Aceto, J. A. Antunes Pereira, M. Cangkrama, H. Gehart, Z. Kontarakis, W. Kovacs, A. Leitner, S. L. Masneuf, P. Picotti, U. Sauer, E. B. Truernit, A. Wutz, N. Zamboni | |
| Abstract | This introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three praktikum days in: - Plant Biology - Animal Models - Genomics - Molecular Systems Biology (total of 12 experiments) Each experiment takes one full day. | ||||
| Learning objective | Introduction to theoretical and experimental biology General Praktikum-information and course material: Moodle The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail). | ||||
| Content | The class is divided into four blocks: Cell Biology, Plant Biology, Genomics AND Molecular Systems Biology. One block lasts three weeks. Animal Models: - Tissue structure and biology - Mouse anatomy and histology - Tissue repair and cancer GENOMICS: - Chromosome preparations from mammalian cells - Genome Editing - Cancer genomics Molecular Systems Biology: - Preparation of proteomics and metabolomics samples - Analysis of proteomics and metabolomics data - Interpretation of proteomics and metabolomics data PLANT BIOLOGY: - Plants and light - Phytohormones and other growth factors - Molecular biology of systemic gene silencing | ||||
| Lecture notes | Laboratory manuals All scripts and additional course information is available on Moodle. | ||||
| Prerequisites / Notice | THE PRAKTIKUM RULES: Your attendance is obligatory and you have to attend all 12 Praktikum days. Absences are only acceptable if you are able to provide a Doctor’s certificate. The original Dr's certificate has to be given to Dr. M. Gstaiger (HPM F43) within five days of the absence of the Praktikum day. If there will be any exceptional or important situations then you should directly contact the Director of Studies of D-Biol, who will decide if you are allowed to miss a Praktikum day or not. HIGHLY IMPORTANT!! 1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS21 but not later than 2.2.2022. 2. Later registration is NOT possible and can NOT be accepted! 3. The course registration for FS22 is usually possible at the end of HS21 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible. Students can register for a practice group via myStudies. As soon as the course unit is registered in myStudies, a text box appears indicating that a group can be selected. Accordingly, students can select a group in the next step. If more than 180 students register, the surplus students will be placed on a waiting list and then allocated by the course responsible. The Praktikum GL BioII FS22 will take place during the following days and therefore, you have to make sure already now that you do not have any other activities & commitments during these days: PRAKTIKUM DAYS DURING FS22 (Monday): 21.02.; 28.02.; 07.03.; 14.03.; 21.03.; 28.03.; 04.04.; 11.04.; 02.05.; 09.05.; 16.05.; 23.05.; No Praktikum during the Easter break: 18.04-29.04. | ||||
| 551-0326-00L | Cell Biology | 6 credits | 4V | S. Werner, N. Aceto, H. Gehart, W. Kovacs, M. Schäfer, U. Suter, A. Wutz | |
| Abstract | This Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism. | ||||
| Learning objective | -To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project. -To convey knowledge about neuron-glia interactions in health and disease. - To provide information on different types of stem cells and their function in health and disease -To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases -To convey knowledge on the mechanisms underlying repair of injured tissues -To provide the students with an overview of mitochondrial dynamics. -Providing an understanding of RNA processing reactions and their regulations. -To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses. -To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level. -Providing the background and context that foster cross-disciplinary scientific thinking. | ||||